Results 41 to 50 of about 68,717 (285)

On the role of the corpus callosum in interhemispheric functional connectivity in humans [PDF]

open access: yes, 2017
Resting state functional connectivity is defined in terms of temporal correlations between physiologic signals, most commonly studied using functional magnetic resonance imaging. Major features of functional connectivity correspond to structural (axonal)
Hacker, Carl D.   +8 more
core   +2 more sources

Dexmedetomidine does not produce vasocontraction on human isolated gastroepiploic artery [PDF]

open access: yesKorean Journal of Anesthesiology, 2011
BackgroundRecently, the addition of dexmedetomidine to sedation regimens after cardiac surgery had been reported and there is a possibility that dexmedetomidine can cause vasoconstriction.
Won-Sung Kim   +5 more
doaj   +1 more source

A comparison of dexmedetomidine and midazolam for sedation in third molar surgery [PDF]

open access: yes, 2007
This randomised, double-blind study compared dexmedetomidine and midazolam for intravenous sedation during third molar surgery under local anaesthesia.
Aantaa   +25 more
core   +1 more source

Dexmedetomidine Inhibits Maturation and Function of Human Cord Blood-Derived Dendritic Cells by Interfering with Synthesis and Secretion of IL-12 and IL-23. [PDF]

open access: yesPLoS ONE, 2016
To investigate the effects and underlying mechanism of dexmedetomidine on the cultured human dendritic cells (DCs).Human DCs and cytotoxic T lymphocytes (CTLs) were obtained from human cord blood mononuclear cells by density gradient centrifugation ...
Gong Chen   +9 more
doaj   +1 more source

The Current Role of Dexmedetomidine as Neuroprotective Agent: An Updated Review

open access: yesBrain Sciences, 2021
Dexmedetomidine, selective α2-adrenergic agonist dexmedetomidine, has been widely used clinically for sedation and anesthesia. The role of dexmedetomidine has been an interesting topic of neonatological and anesthetic research since a series of ...
Zaara Liaquat   +4 more
doaj   +1 more source

Inhibiting Liver‐Derived C3 Protein Rescues Anesthesia/Surgery‐Induced Cognitive Impairment, Synaptic Disorders, and Microglial Phagocytosis

open access: yesAdvanced Science, EarlyView.
This study provides evidence that anesthesia/surgery can induce the BBB breakdown and promote the release of hepatogenous C3 protein into the blood. This surgical dual factors ultimately drove C3 to cross the damaged BBB and selectively colocalize with C3aR in the hippocampus, which results in structural and functional injury of synapse, C3aR‐mediated ...
Qianqian Wu   +17 more
wiley   +1 more source

The Intraoperative Microlesion Effect Positively Correlates With the Short‐Term Clinical Effect of Deep Brain Stimulation in Parkinson's Disease

open access: yesNeuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objective During the surgical procedure of deep brain stimulation (DBS), insertion of an electrode in the subthalamic nucleus (STN) frequently causes a temporary improvement of motor symptoms, known as the microlesion effect (MLE). The objective of this study was to determine the correlation between the intraoperative MLE and the clinical ...
Stèfan F. Lange   +8 more
wiley   +1 more source

Dexmedetomidine with different concentrations added to local anesthetics in erector spinae plane block: a meta-analysis of randomized controlled trials

open access: yesFrontiers in Medicine
BackgroundDexmedetomidine has been used as a perineural local anesthetic (LA) adjuvant to facilitate the potency of erector spinal plane block (ESPB). This quantitative review aimed to evaluate whether perineural dexmedetomidine for ESPB can improve the ...
Qian Li   +8 more
doaj   +1 more source

Emergency Palliative Cancer Care: Dexmedetomidine Treatment Experiences—A Retrospective Brief Report on Nine Consecutive Cases

open access: yesPain and Therapy, 2023
Introduction Dexmedetomidine, an alpha-2 adrenergic receptor agonist with potential opioid sparing properties, is utilized in palliative medicine, but the knowledge base for this practice is limited.
Erik Torbjørn Løhre   +5 more
doaj   +1 more source

Correlative Imaging Platform Linking Taste Cell Function to Molecular Identity

open access: yesAdvanced Science, EarlyView.
A correlative imaging platform is developed to study how individual taste cells respond to different taste qualities. By linking cellular activity with molecular identity and environmental context, dual‐tuned taste cells capable of detecting both sweet and umami stimuli are identified.
Sungho Lee   +6 more
wiley   +1 more source

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