Results 61 to 70 of about 65,011 (307)

Mitochondrial Regulation of CD8⁺ T Cells: Mechanisms and Therapeutic Modulation

Advanced Science, EarlyView.
This article comprehensively explores the pivotal role of mitochondrial function in CD8⁺ T cell immunotherapy. It highlights how mitochondrial dynamics regulate T cell activation, differentiation, and persistence, and how mitochondrial dysfunction leads to immune exhaustion and impaired antitumor/antiviral responses.
Xu Chen, Pei Lin, Ye Lu, Jiarong Zheng, Yunfan Lin, Zihao Zhou, Li Cui, Xinyuan Zhao   +7 more
wiley   +1 more source

Effect of intraoperative dexmedetomidine on renal function after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy: a randomized, placebo-controlled trial

International Journal of Hyperthermia, 2019
Introduction: Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) predispose to postoperative renal dysfunction. Dexmedetomidine is an α2 adrenoreceptor agonist, which has renoprotective effects after cardiac surgery ...
Young Song, Do-Hyeong Kim, Tae Dong Kwon, Dong Woo Han, Seung Hyuk Baik, Hwan Ho Jung, Ji Young Kim   +6 more
doaj   +1 more source

Perbandingan Pemberian Dexmedetomidine dengan Fentanyl Intraoperatif terhadap Kedalaman Anestesia dan Kecepatan Pemulihan pada Operasi Bedah Saraf

Jurnal Neuroanestesi Indonesia, 2022
Latar Belakang dan Tujuan: Anestesi bebas opioid merupakan diskusi baru dalam dunia anestesi. Bukti menunjukkan bahwa opioid memiliki efek samping yang tidak diinginkan. Dexmedetomidine merupakan suatu reseptor agonis a2-adrenergik selektif yang memiliki
Zafrullah Kany Jasa, Teuku Heriansyah, Muttaqin Muttaqin   +2 more
doaj   +1 more source

Personalized Kirigami Strain Sensors for in vivo Applications

Advanced Intelligent Systems, EarlyView.
Rapid prototyping of strain sensors is demonstrated using a laser cutter that both converts carbon‐based material to strain responsible graphene and generates cuts in a kirigami‐style pattern that allows enhanced substrate flexibility. This method is used to generate wearable sensors for monitoring heart rate, limb/finger motion, and abdominal ...
Siheng Sean You, Max Schober, Soufyane Ben‐Ayed, Sahab Babaee, Stephanie Owyang, Josh Jenkins, Peter R. Chai, Giovanni Traverso   +7 more
wiley   +1 more source

Dexmedetomidine hydrochloride as a long-term sedative

Therapeutics and Clinical Risk Management, 2011
Takayuki KunisawaSurgical Operation Department, Asahikawa Medical University Hospital, Asahikawa, Hokkaido, JapanAbstract: Dexmedetomidine undoubtedly is a useful sedative in the intensive care setting because it has a minimal effect on the respiratory ...
Kunisawa T
doaj  

A comparison of dexmedetomidine and midazolam for sedation in third molar surgery [PDF]

, 2007
This randomised, double-blind study compared dexmedetomidine and midazolam for intravenous sedation during third molar surgery under local anaesthesia.
Aantaa, Angst, Arain, Aun, Bloor, Cortinez, Dob, Ebert, Esen, Gan, Gurbet, Hall, Hsu, Leitch, MacDonald, Ong, Ramsay, Richards, Robin, Rodrigo, Savin, Smith, Tombaugh, Unlugenc, Venn, Wijeysundera   +25 more
core   +1 more source

Practical management of repeated life‐threatening status epilepticus in Alternating Hemiplegia of Childhood: Case report and literature review

Epileptic Disorders, EarlyView.
Abstract Background Alternating Hemiplegia of Childhood (AHC) is a severe channelopathy that manifests before 18 months of age, primarily caused by pathogenic variants in the ATP1A3 gene. It is characterized by recurrent and disabling episodes of plegia, dystonia, dysautonomia, along with chronic neurological features and cardiac arrhythmias. About 50%
Ramona Cordani, Livia Pisciotta, Michela Stagnaro, Maria Margherita Mancardi, Elisabetta Lampugnani, Luca Manfredini, Lino Nobili, Edvige Veneselli, Elisa De Grandis   +8 more
wiley   +1 more source

Dexmedetomidine Inhibits TLR4/NF-κB Activation and Reduces Acute Kidney Injury after Orthotopic Autologous Liver Transplantation in Rats [PDF]

, 2015
published_or_final_versio
Cai, J, Chi, X, Huang, P, Jin, Y, Wang, Y, Wu, S, Xia, Z, Yao, H   +7 more
core   +1 more source

Median effective dosage of midazolam oral solution for preschool children in preoperative sedation

Ibrain, EarlyView.
This study aimed to detect median effective dosage (ED50) of midazolam oral solution (MOS) for preschool children in preoperative sedation. Thirty children who were scheduled for elective of the hidden penis correction surgery under general anesthesia in the pediatric surgery department were selected.
Rui Jiang, De‐Chuan Wang, Nan Zhao, Ke An, Yi‐Nan Zhang, Zhao‐Qiong Zhu   +5 more
wiley   +1 more source

Intraoperative dexmedetomidine-induced polyuria from a loading dose: a case report

Journal of International Medical Research, 2020
With extensive perioperative use of dexmedetomidine, there has been rising concern about its side effects, which are most commonly bradycardia and hypotension.
Zhang Chen, Ting Chen, Haiwang Ye, Junping Chen, Bo Lu   +4 more
doaj   +1 more source