Results 71 to 80 of about 65,011 (307)

Disruption of thalamic functional connectivity is a neural correlate of dexmedetomidine-induced unconsciousness [PDF]

open access: yes, 2014
Understanding the neural basis of consciousness is fundamental to neuroscience research. Disruptions in cortico-cortical connectivity have been suggested as a primary mechanism of unconsciousness.
Akeju, Oluwaseun   +15 more
core   +3 more sources

Research progress on the depth of anesthesia monitoring based on the electroencephalogram

open access: yesIbrain, Volume 11, Issue 1, Page 32-43, Spring 2025.
Electroencephalogram (EEG) can noninvasive, continuous, and real‐time monitor the state of brain electrical activity, and the monitoring of EEG can reflect changes in the depth of anesthesia (DOA). The development of artificial intelligence can enable anesthesiologists to extract, analyze, and quantify DOA from complex EEG data.
Xiaolan He, Tingting Li, Xiao Wang
wiley   +1 more source

Incidence of acute kidney injury after noncardiac surgery in patients receiving intraoperative dexmedetomidine: a retrospective study

open access: yesBJA Open, 2023
Background: Postoperative acute kidney injury (AKI) is a common complication and is associated with increased hospital length of stay and 30 day all-cause mortality.
Manuel A. Paredes-Flores   +10 more
doaj  

Retrospective Evaluation of the Epidemiology and Practice Variation of Dexmedetomidine Use in Invasively Ventilated Pediatric Intensive Care Admissions, 2007-2013 [PDF]

open access: yes, 2015
OBJECTIVES: The study assessed dexmedetomidine utilization and practice variation over time in ventilated pediatric intensive care unit (PICU) patients; and evaluated differences in hospital outcomes between high- and low-dexmedetomidine utilization ...
Benneyworth, Brian D.   +2 more
core   +1 more source

Losing brain networks during death

open access: yesInterdisciplinary Medicine, EarlyView.
Abstract Death represents the end of all living organisms. The pattern of brain activity disappearance following death, however, has not been fully elucidated. Here we investigated brain activity dynamics following cardiac arrest using ultra‐high field 11.7 T magnetic resonance imaging (MRI) in longitudinal approach and multi‐modal analyses. Initially,
Han Li   +22 more
wiley   +1 more source

New Endoscopic Strategy for Ampullary Tumor and Superficial Nonampullary Duodenal Epithelial Tumor Extending Into Papillary Area

open access: yesJournal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Background and Study Aim Endoscopic papillectomy (EP) is widely performed for avoiding high‐risk surgeries. However, recurrence rates are high, and lateral extension is a risk for recurrence. With endoscopic submucosal dissection (ESD), even lesions with lateral extensions are able to be en bloc resected, and may reduce that risk.
Takashi Hirose   +9 more
wiley   +1 more source

In Vitro Effect of Dexmedetomidine on Platelet Aggregation

open access: yesBrazilian Journal of Anesthesiology, 2013
Background and objectives: : Dexmedetomidine is a selective α2-agonist. There are 250-300 α2- adrenoceptor on the surface of each human platelet and ephedrine induces platelet aggregation by binding these receptors.
Emine Arzu Kose   +3 more
doaj  

Emergency Palliative Cancer Care: Dexmedetomidine Treatment Experiences—A Retrospective Brief Report on Nine Consecutive Cases

open access: yesPain and Therapy, 2023
Introduction Dexmedetomidine, an alpha-2 adrenergic receptor agonist with potential opioid sparing properties, is utilized in palliative medicine, but the knowledge base for this practice is limited.
Erik Torbjørn Løhre   +5 more
doaj   +1 more source

Systematic review of the behavioural assessment of pain in cats [PDF]

open access: yes, 2016
Objectives The objectives were to review systematically the range of assessment tools used in cats to detect the behavioural expression of pain and the evidence of their quality; and to examine behavioural metrics (considering both the sensory and ...
Brondani JT   +11 more
core   +1 more source

Dexmedetomidine Blocks the ERK Pathway by Inhibiting MAP3K8 to Achieve a Protective Effect in Lung Ischemia/Reperfusion Injury

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Lung ischemia/reperfusion injury (LIRI) is a primary contributor to morbidity and mortality following lung transplantation. Dexmedetomidine (DEX) protects the lungs from I/R injury, but the underlying mechanisms remain uncertain. This paper examined the protective effect of DEX in LIRI and elucidated the potential regulation involved. LIRI was
Chun‐Huan Hu   +4 more
wiley   +1 more source

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