Results 41 to 50 of about 284,775 (299)

Johnson-Kendall-Roberts theory applied to living cells [PDF]

, 2005
Johnson-Kendall-Roberts (JKR) theory is an accurate model for strong adhesion energies of soft slightly deformable material. Little is known about the validity of this theory on complex systems such as living cells. We have addressed this problem using a
A. S. G. Curtis, A. Tozeren, A. Yeung, D. R. Friedlander, E. D. Shchukin, E. Evans, E. Evans, E. Evans, E. Evans, G. Segal, I. Spector, K. L. Johnson, K.-l. P. Sung, M. S. Turner, N. Mohandas, P-G. de Gennes   +15 more
core   +5 more sources

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Osmotic pressure: resisting or promoting DNA ejection from phage [PDF]

, 2008
Recent in vitro experiments have shown that DNA ejection from bacteriophage can be partially stopped by surrounding osmotic pressure when ejected DNA is digested by DNase I on the course of ejection.
Castelnovo, Martin, Evilevitch, Alex,, Jeembaeva, Meerim,, Larsson, Frida, Lund University.   +4 more
core   +3 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

The Discovery, Molecular Cloning, and Characterization of Dextransucrase LmDexA and Its Active Truncated Mutant from Leuconostoc mesenteroides NN710

Molecules
Dextransucrases play a crucial role in the production of dextran from economical sucrose; therefore, there is a pressing demand to explore novel dextransucrases with better performance.
Xiaoqiong Zuo, Lixia Pan, Wenchao Zhang, Jing Zhu, Yan Qin, Xiuying Xu, Qingyan Wang   +6 more
doaj   +1 more source

An introductory report on the effect of use of dextranase-containing mouthwash on oral health status of human volunteers

Asian Journal of Medical Sciences, 2020
Background: Dextran is a branched polysaccharide and one of the polymers, present in the biofilm matrix. The dextran plays a perilous role in dental plaque formation, which is involved in the development of some common oral diseases like dental caries ...
Nucharee Juntarachot , Bhagavathi Sundaram Sivamaruthi, Sasithorn Sirilun, Piyachat Tongpong, Phakkharawat Sittiprapaporn, Duangporn Kantachote, Chaiyavat Chaiyasut   +6 more
doaj   +1 more source

Effect of anti-adhesion agents on cytokine profile in an experimental model of postoperative intra-abdominal adhesions

Хірургія дитячого віку, 2023
Many attempts have been made to prevent peritoneal adhesions using anti-adhesion agents, barriers and other therapeutic approaches, but their efficacy has not been widely accepted.
F.T. Akhmedov, H.B. Isayev, S.V. Guliyeva   +2 more
doaj   +1 more source

Improvement of lung preservation - From experiment to clinical practice [PDF]

, 2002
Background. Reperfusion injury represents a severe early complication following lung transplantation. Among the pathogenetic factors, the high potassium content of Euro-Collins(R) solution is discussed.
Bittmann, I., Fürst, H., Hatz, Rudolf A., Kellner, B., Müller, Ch., Reichart, B., Schelling, G., Schildberg, Friedrich Wilhelm   +7 more
core   +1 more source

Strategies for Loading and Releasing Peptide Therapeutics in Biodegradable Carriers

Advanced Functional Materials, Volume 36, Issue 44, 1 June 2026.
A biodegradable carrier‐based peptide delivery system is a powerful treatment platform for diverse diseases, owing to its superior therapeutic efficacy and low toxicity. This review examines the conventional peptide‐loaded carrier fabrication process and its current limitations.
Wookyoung Jang, Ki Wan Bong
wiley   +1 more source

Air-Assisted Electrospinning of Dihydromyricetin-Loaded Dextran/Zein/Xylose Nanofibers and Effects of the Maillard Reaction on Fiber Properties

Molecules
Dihydromyricetin (DMY) has been encapsulated in delivery systems to address the solubility limitations of DMY in water and improve its bioavailability. Air-assisted electrospinning has been used as a novel technology to load DMY.
Yupeng Ren, Jianhui An, Cheng Tian, Longchen Shang, Yexing Tao, Lingli Deng   +5 more
doaj   +1 more source