Results 181 to 190 of about 98,007 (275)

Characterisation of bacteria‐induced colitis and its modulation by probiotics in naked mole rats: a new mammalian model for acute inflammatory disease

open access: yesThe Journal of Pathology, Volume 268, Issue 4, Page 493-511, April 2026.
Abstract Enteropathogenic bacteria are a major cause of morbidity and mortality globally. While mouse models have been indispensable in advancing our understanding of infectious enteric diseases, key differences in intestinal microbiota and immunobiology between mice and humans underscore the need for alternative mammalian models that better ...
Daniel W. Hart   +14 more
wiley   +1 more source

Functional humanization of 15-lipoxygenase-1 (Alox15) protects mice from dextran sodium sulfate induced intestinal inflammation. [PDF]

open access: yesCell Mol Biol Lett
Reisch F   +8 more
europepmc   +1 more source

Rhizobacteria Exopolysaccharide: A Boon in Reclaiming Soil Fertility, Augmenting Plant Growth and Plant Stress Resilience

open access: yesEnvironmental Microbiology Reports, Volume 18, Issue 2, April 2026.
Microbial exopolysaccharides (EPS) enhance plant stress tolerance and soil health by improving water retention, nutrient cycling, and resilience to salinity and heavy metals, offering a biodegradable and eco‐friendly alternative to synthetic polymers for sustainable agriculture. ABSTRACT Microbial exopolysaccharides (EPSs) serve multiple industrial and
Aishmita Gantait   +4 more
wiley   +1 more source

Variation in Microbiome Composition and Faecal Metabolites Are Associated With Differential Susceptibility to DSS‐Induced Colitis

open access: yesImmunology, Volume 177, Issue 4, Page 766-783, April 2026.
C57BL/6 mice from Charles River Laboratories (CR) have enhanced mucosal immune action relative to C57BL/6 mice from Jackson Laboratories (JAX). CR mice are more susceptible to severe DSS‐induced colitis than JAX mice. Co‐housing transfers colitis susceptibility from CR mice to JAX mice.
Jessica M. Till   +8 more
wiley   +1 more source

Short‐Chain Fatty Acids Activate Myenteric Neurons and Delay Colonic Motility via Free Fatty Acid Receptors 2 and 3 in the Mouse

open access: yesNeurogastroenterology &Motility, Volume 38, Issue 4, April 2026.
Short‐chain fatty acids (SCFAs), including propionate, acetate, and butyrate, activate IPANs and myenteric neurons and delay colonic motility via FFAR2 and FFAR3. GLPG0976 and β‐hydroxybutyrate (BHB) were used as selective antagonists for FFAR2 and FFAR3, respectively, to confirm receptor‐specific effects.
Preedajit Wongkrasant   +4 more
wiley   +1 more source

Immunomodulatory effects of cathelicidin in the gut–brain axis: A novel link between mucosal immunity and neuroinflammation

open access: yesExperimental Physiology, Volume 111, Issue 4, Page 1733-1745, 1 April 2026.
Abstract Cathelicidins are evolutionarily conserved host defence peptides known for their dual antimicrobial and immunomodulatory functions. Among them, LL‐37 in humans and CRAMP in rodents have emerged as crucial regulators of both mucosal immunity and CNS inflammation.
Mehrdad Nourizadeh   +6 more
wiley   +1 more source

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