Rosa roxburghii‐derived exosome‐like nanovesicles target the intestine, repairing barriers, regulating gut microbiota, balancing Th17/Treg, and combating oxidative stress/inflammation to alleviate colitis, a promising UC therapy. ABSTRACT Plant‐derived nanovesicles (PDVs), an innovative and bioactive form of natural products, are key mediators of ...
Yuanyuan Wang +8 more
wiley +1 more source
Integrated Macrogenomics and Metabolomics Analysis of the Effect of Sea Cucumber Ovum Hydrolysates on Dextran Sodium Sulfate-Induced Colitis. [PDF]
Gong S +11 more
europepmc +1 more source
This study employed an ultrasonic‐assisted extraction (UAE) method combined with column chromatography purification to obtain two homogeneous polysaccharides (CVP‐I and CVP‐II) from Conioselinum vaginatum, which exhibited distinct physicochemical properties and structural characteristics, and exerted anti‐inflammatory effects by inhibiting the ...
Conghui Ren +6 more
wiley +1 more source
The Use of Potent Populations of Expanded Fetal Human Placental Stromal Cells for the Treatment of Dextran Sodium Sulfate-Induced Colitis in a Mouse Model. [PDF]
Gorodetsky R +5 more
europepmc +1 more source
LL‐37: Biological Mechanisms and Emerging Therapeutic Applications in Intestinal Disease
ABSTRACT Human cathelicidin peptide LL‐37 is encoded by the CAMP gene and plays a key role in innate immunity. It maintains intestinal homeostasis through antibacterial, immunomodulation, and tissue repair functions. This paper reviews the multiple functions of LL‐37 in the intestinal‐immune axis and its contribution to intestinal immune homeostasis. A
Qichao Liu, Peng Xu, Cheng Zhang
wiley +1 more source
Unveiling Colitis: A Journey through the Dextran Sodium Sulfate-induced Model. [PDF]
Yang C, Merlin D.
europepmc +1 more source
Macrophage‐Targeting Biomaterials for Osteoarthritis Therapy
Macrophage‐Targeting Biomaterials for Osteoarthritis Therapy. Created in BioRender. Jain, E. (2026) https://BioRender.com/x4f9o8g. ABSTRACT Osteoarthritis (OA) is a highly prevalent, disabling, and painful disease of the joints, characterized by progressive cartilage degeneration, synovial fibrosis, and pain.
Era Jain, Paul Nana Kwame Sagoe
wiley +1 more source
Octreotide Counteracts IFN‐γ‐Induced Endothelial Inflammation
ABSTRACT Endothelial cells maintain vascular homeostasis through the regulation of permeability and coagulation. Interferon‐gamma (IFN‐γ), a proinflammatory cytokine released by activated T lymphocytes and natural killer cells, disrupts endothelial junctional integrity, leading to barrier dysfunction.
Saikat Fakir +3 more
wiley +1 more source
Korean Red Ginseng alleviates dextran sodium sulfate-induced colitis through gut microbiota modulation in mice. [PDF]
Jeong JS +10 more
europepmc +1 more source
THE USE OF COMBINED PRESERVATION TECHNIQUES FOR EXTENDED STORAGE OF ORTHOTOPIC LIVER HOMOGRAFTS. [PDF]
Brettschneider, Lawrence +7 more
core +1 more source

