Korean Red Ginseng alleviates dextran sodium sulfate-induced colitis through gut microbiota modulation in mice. [PDF]
Jeong JS +10 more
europepmc +1 more source
Carrageenans, widely used food additives, disrupted intestinal epithelial integrity in a gut‐on‐a‐chip model. All types (κ‐, ɩ‐, λ‐) induced cytotoxicity, inflammation and tight junction (TJ) disruption, triggering TNF‐mediated immune responses. λ‐Carrageenan had the most severe effects, supporting the Epithelial Barrier Theory linking food additives ...
Na Sun +13 more
wiley +1 more source
Lipidated IL-22 Alone or Combined with Immunomodulatory Agents Improves Disease Endpoints and Promotes Mucosal Healing in a Mouse Model of Chronic Dextran Sodium Sulfate-Induced Colitis. [PDF]
Støy S +7 more
europepmc +1 more source
This study employed an integrated multi‐omics screening strategy incorporating GEO database differential expression analysis, GWAS‐eQTL genetic association analysis, and single‐cell RNA‐seq cell subpopulation localization to identify EPHX2 as a core causal gene in ulcerative colitis (UC).
Tian Dai +8 more
wiley +1 more source
Protective effect of tryptophan against dextran sulfate sodium- induced experimental colitis
Toru SHIZUMA +2 more
doaj +1 more source
Polygonatum cyrtonema polysaccharides reshape the gut microbiota to ameliorate dextran sodium sulfate-induced ulcerative colitis in mice. [PDF]
Lin C +10 more
europepmc +1 more source
An update on the landscape of collagen bioactive fragments
The remodeling of the extracellular matrix releases collagen bioactive fragments, which exert molecular functions and regulate numerous biological processes via several signaling pathways. Here, we summarize the latest findings describing the roles of major bioactive fragments from collagens I, IV, VI, and XVIII in various physiological and ...
Sylvie Ricard‐Blum, Julie Fradette
wiley +1 more source
Amelioration of Dextran Sodium Sulfate-Induced Colitis in Mice through Oral Administration of Palmitoylethanolamide. [PDF]
Trivedi P +6 more
europepmc +1 more source
Intestinal Epithelial Cell-Related Alternative Splicing Events in Dextran Sodium Sulfate-Induced Acute Colitis. [PDF]
europepmc +1 more source
Berberine enhances IL‐10 production in macrophages via FASN‐dependent mechanisms, thereby promoting epithelial repair and preventing colitis relapse. Created with BioRender.com. ABSTRACT Inflammatory bowel disease (IBD) is a chronic inflammatory disorder characterized by alternating periods of remission and relapse.
Shusaku Hayashi +8 more
wiley +1 more source

