Results 211 to 220 of about 98,592 (289)

Novel GH115 xylan α‐1,2‐glucuronidases with distinct preferences for xylan‐derived oligomers and polymers

Protein Science, Volume 35, Issue 5, May 2026.
Abstract Natural polymers are promising sustainable materials for diverse applications. Xylans, major components of hemicellulose, exhibit origin‐dependent substitution patterns that determine their physicochemical properties. Targeted enzymatic modification of these substituents offers a mild and precise approach for tailoring the polymer's ...
Savvina Leontakianakou, Simone Balzer Le, Anders Sundin, Andrius Jasilionis, Giang‐Son Nguyen, Anna Nordborg, Lalitha D. Gottumukkala, Carl Grey, Anna Sofia Lewin, Eva Nordberg Karlsson   +9 more
wiley   +1 more source

Lipidated IL-22 Alone or Combined with Immunomodulatory Agents Improves Disease Endpoints and Promotes Mucosal Healing in a Mouse Model of Chronic Dextran Sodium Sulfate-Induced Colitis. [PDF]

Dig Dis Sci
Støy S, D'Alessio S, Sandahl TD, Dige A, Kjølbye AL, Jorgensen R, Danese S, van de Bunt M.   +7 more
europepmc   +1 more source

Maladaptive Inflammatory Signaling in Old Mice Impairs Colonic Regeneration by Promoting a Sustained Fetal‐Like Epithelial State

Aging Cell, Volume 25, Issue 5, May 2026.
This study explores the impact of aging on regeneration of the mouse colonic epithelium. The authors find that old mice exhibit excessive and prolonged inflammation after infection with Citrobacter, resulting in the maintenance of a fetal regenerative state in epithelial cells, insufficient tissue repair, and death of the animal.
Antonion Korcari, Helen Tauc, Jeff Duggan, Jina Yun, Fabien Wehbe, Spyros Darmanis, Zora Modrusan, Rajita Pappu, David Garfield, Heinrich Jasper, David Castillo‐Azofeifa   +10 more
wiley   +1 more source

Polygonatum cyrtonema polysaccharides reshape the gut microbiota to ameliorate dextran sodium sulfate-induced ulcerative colitis in mice. [PDF]

Front Pharmacol
Lin C, Song D, Wang S, Chu Y, Chi C, Jia S, Lin M, He C, Jiang C, Gong F, Chen Q.   +10 more
europepmc   +1 more source

Hydroxytyrosol Mitigates Anxiety‐Like Behaviors After a Traumatic Experience in Aged Mice in Parallel With Increased Neurogenesis in the Ventral and Dorsal Dentate Gyrus, and Preservation of Gut Microbiota Composition

Journal of Neurochemistry, Volume 170, Issue 5, May 2026.
Hydroxytyrosol (HTyr), a phenolic compound of olive oil, exerts beneficial effects on several age‐related diseases. We previously demonstrated that oral HTyr administration in aging mice enhances hippocampal neurogenesis, known to play a role in memory formation and emotional behaviors. In the present study, we found that HTyr preferentially stimulates
Giorgio D'Andrea, Laura Bertini, Marco Costanzi, Fabiana Canini, Roberta Bernini, Andrea Fochetti, Mariangela Clemente, Silvia Proietti, Manuela Ceccarelli, Carla Caruso, Maurizia Caruso, Ferdinando Scavizzi, Marcello Raspa, Felice Tirone, Laura Micheli   +14 more
wiley   +1 more source

Amelioration of Dextran Sodium Sulfate-Induced Colitis in Mice through Oral Administration of Palmitoylethanolamide. [PDF]

Biomedicines
Trivedi P, Myers T, Ray B, Allain M, Zhou J, Kelly M, Lehmann C.   +6 more
europepmc   +1 more source

Intestinal Epithelial Cell-Related Alternative Splicing Events in Dextran Sodium Sulfate-Induced Acute Colitis. [PDF]

Turk J Gastroenterol, 2023
europepmc   +1 more source

Oridonin‐Loaded PDA@Gel@GO Nanocapsules Modulate NLRP3 and Epithelial Repair in Colitis

The FASEB Journal, Volume 40, Issue 8, 30 April 2026.
Mechanism of galactosylated carboxymethyl chitosan nanomicelle oral microcapsules delivering oridonin in alleviating colitis via targeting the NLRP3 inflammasome. ABSTRACT Ulcerative colitis (UC) is a chronic inflammatory bowel disease marked by sustained mucosal inflammation and epithelial barrier dysfunction, closely associated with aberrant NOD‐like
Wenbo Yuan, Qirui Zhao, Jing Hua, Lingyao Xu, Yufan Wang, Tongtong Xu, Zuchao Du, Liping Wu, Daxiang Cui   +8 more
wiley   +1 more source

Protective effect of tryptophan against dextran sulfate sodium- induced experimental colitis

The Turkish Journal of Gastroenterology, 2013
Toru SHIZUMA, Hidezo MORI, Naoto FUKUYAMA   +2 more
doaj   +1 more source

Therapeutic Effects of Zanthoxyli Pericarpium on Intestinal Inflammation and Network Pharmacological Mechanism Analysis in a Dextran Sodium Sulfate-Induced Colitis Mouse Model. [PDF]

Nutrients
Choi WG, Ko SJ, Jung D, Kim SC, Choi NR, Park JW, Kim BJ.   +6 more
europepmc   +1 more source