Results 251 to 260 of about 98,592 (289)

Dextran Sodium Sulfate-Induced Murine Inflammatory Colitis Model

2013
Colitis is a chronic inflammatory disease of the colon that is characterized by recurring, acute episodes. Mouse models of colitis allow for the study of multiple aspects of this disease, including the innate immune response, epithelial and intestinal cell response, and wound healing.
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Feruloylated Oligosaccharides Alleviate Dextran Sulfate Sodium-Induced Colitis in Vivo

Journal of Agricultural and Food Chemistry, 2019
The imbalance of T lymphocyte subsets substantially conduces to disturbed intestinal immune system and succeeding colonic tissue damage in inflammatory bowel diseases. It is considered that regulation of phytochemicals on cytokine production potentially provides a broad prospect for the exploitation of immunomodulatory agents.
Xichun Xia, Leqing Zhu, Zhiwei Lei, Yueqi Song, Fen Tang, Zhao Yin, Jing Wang, Junqing Huang   +7 more
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[Experimental colitis induced by dextran sulfate sodium].

Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University, 2001
In this study, experimental colitis in rats induced by dextran sulfate sodium (DSS) was performed. Twenty rats freely drank 3% DSS solution for 10 days. During the 10 days, symptoms (diarrhea, hemafecia) were observed daily, and at the same time the rats were colon-endoscopied.
X, Wu, Q, Ling
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Venular Constriction of Submucosal Arterioles Induced by Dextran Sodium Sulfate

Inflammatory Bowel Diseases, 2005
Leukocyte and platelet adherence in postcapillary venules has been speculated to induce constriction of closely paired arterioles. This mechanism was investigated in the current study, in a model of intestinal inflammation induced by dextran sodium sulfate (DSS; 5,000 molecular weight).Closely paired, parallel arterioles and venules in the submucosa of
Norman R, Harris, Joseph R, Whatley, Patsy R, Carter, Robert D, Specian   +3 more
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Dextran sodium sulfate alters cytokine production in macrophages in vitro.

Die Pharmazie, 2016
Macrophages have been assumed to have a crucial role in the development of inflammatory bowel disease (IBD). However, involvement of intestinal macrophages in IBD onset and functional alterations of macrophages during IBD development has not been clarified.
Kono, Y., Miyoshi, S., Fujita, T.
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Intestinal E-cadherin Deficiency Aggravates Dextran Sodium Sulfate-Induced Colitis

Digestive Diseases and Sciences, 2015
E-cadherin is a cell adhesion protein with crucial roles in development, tissue homeostasis, and disease. Loss of E-cadherin in the adult intestinal epithelium disrupts tissue architecture and is associated with impaired localization and function of goblet and Paneth cells, reduced expression of antibacterial factors, and deficiency in clearing ...
Jessica I, Grill, Jens, Neumann, Felix, Hiltwein, Frank T, Kolligs, Marlon R, Schneider   +4 more
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Keratinocyte Growth Factor Ameliorates Dextran Sodium Sulfate Colitis in Mice

Digestive Diseases and Sciences, 1999
Keratinocyte growth factor (KGF) is emerging as an important mediator of mucosal defense and repair in the colon. The aim of the present study was to evaluate and further characterize the effects of exogenous KGF administration utilizing the dextran sodium sulfate (DSS) model of colitis in mice.
B, Egger, F, Procaccino, I, Sarosi, J, Tolmos, M W, Büchler, V E, Eysselein   +5 more
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Dextran sulfate sodium-induced colitis in piglets

2018
Inflammatory bowel disease (IBD) results from complex interactions between genetic and environmental factors.Although a genetic contribution has been proven, dietary factors have also shown to play a role in the developmentof IBD.This study aims to investigate the effect of adding red meatto the diet of piglets in a dextran sodium sulfate (DSS ...
Nielsen, Katrine Dalby, Schramm, Andreas, Purup, Stig, Lauridsen, Charlotte, Canibe, Nuria   +4 more
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PACAP provides colonic protection against dextran sodium sulfate induced colitis

Journal of Cellular Physiology, 2008
AbstractPituitary adenylate cyclase‐activating polypeptide (PACAP) plays a crucial role in immunity and inflammation. Our aim was to obtain insight in the role of PACAP in experimental colitis in mice and thus its possible role in inflammatory bowel disease.
Yasu-Taka, Azuma, Kiyomi, Hagi, Norihito, Shintani, Mitsuru, Kuwamura, Hidemitsu, Nakajima, Hitoshi, Hashimoto, Akemichi, Baba, Tadayoshi, Takeuchi   +7 more
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Daucosterol suppresses dextran sulfate sodium (DSS)-induced colitis in mice

International Immunopharmacology, 2019
The effects of daucosterol have been identified in cancer therapy and neuronal diseases. However, the regulatory function of daucosterol in DSS-induced colitis has not yet been investigated. In this study, we evaluated the immunological and therapeutic effects of daucosterol in a mouse model of dextran sulfate sodium (DSS)-induced colitis.
Jin, Jang, Su-Man, Kim, Su-Min, Yee, Eun-Mi, Kim, Eun-Hee, Lee, Ha-Rim, Choi, Young-Sil, Lee, Won-Kyung, Yang, Han-Young, Kim, Kun-Hoae, Kim, Hyung-Sik, Kang, Seung-Hyung, Kim   +11 more
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