Lactobacillus plantarum Lac16 alleviates dextran sodium sulfate-induced colitis in mice by suppressing NLRP3 inflammasome overactivation through microbiota-derived isobutyric acid. [PDF]
Zhou Y +6 more
europepmc +1 more source
This paper introduces a single‐channel H‐junction microfluidic assay that profiles fibrin's evolving function in repair and thrombosis by measuring, in one ∼3 µL gel, permeability, fibrinolysis kinetics, fibroblast invasion, and clot extension in real time.
Halston Deal +9 more
wiley +1 more source
Functional humanization of 15-lipoxygenase-1 (Alox15) protects mice from dextran sodium sulfate induced intestinal inflammation. [PDF]
Reisch F +8 more
europepmc +1 more source
Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization
This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin +11 more
wiley +1 more source
Reducing dextran sodium sulfate interference with gene expression quantification in a mouse model of colitis. [PDF]
Hechter D, Good SV.
europepmc +1 more source
Adhesion‐Related Macrophages Regulate Metabolic Homeostasis Through CAV‐1 Dependency
Adipose tissue harbors a distinct macrophage subpopulation, termed adhesion‐related macrophages (ARMs), which stably adhere to adipocytes. In obesity, ARMs represent the major expanding macrophage subset. They acquire material from adipocytes and rely on Caveolin‐1 for sustained lipid handling.
Wanyu Hu +23 more
wiley +1 more source
Studies on the alleviating effect of Bifidobacterium lactis V9 on dextran sodium sulfate-induced colitis in mice. [PDF]
Duan X +6 more
europepmc +1 more source
Ecological and dynamic analysis of gut microbiota in the early stage of azomethane-dextran sodium sulfate model in mice. [PDF]
Sun R +5 more
europepmc +1 more source
This study identifies vacuole membrane protein 1 (VMP1) as a critical regulator of intestinal epithelial barrier homeostasis. VMP1 facilitates the recruitment of CORO1C to late endosomes, supporting Retromer‐mediated recycling of the tight junction protein Occludin.
Jiawei Zhao +12 more
wiley +1 more source
Protopine Alleviates Dextran Sodium Sulfate-Induced Ulcerative Colitis by Improving Intestinal Barrier Function and Regulating Intestinal Microbiota. [PDF]
Yue M +5 more
europepmc +1 more source

