Results 261 to 270 of about 650,495 (350)

Intrarectal administration of oxygenated perfluorodecalin promotes healing of murine colitis by targeting inflammatory hypoxia [PDF]

open access: yes, 2011
De Vos, Martine   +4 more
core  

Octreotide Counteracts IFN‐γ‐Induced Endothelial Inflammation

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 40, Issue 5, May 2026.
ABSTRACT Endothelial cells maintain vascular homeostasis through the regulation of permeability and coagulation. Interferon‐gamma (IFN‐γ), a proinflammatory cytokine released by activated T lymphocytes and natural killer cells, disrupts endothelial junctional integrity, leading to barrier dysfunction.
Saikat Fakir   +3 more
wiley   +1 more source

Early Post‑Traumatic Osteoarthritis Features Greater Cartilage Extracellular Matrix Proteoglycan Loss Compared to the Pericellular Matrix

open access: yesJournal of Orthopaedic Research, Volume 44, Issue 5, May 2026.
ABSTRACT Proteoglycan loss in articular cartilage is a hallmark of post‐traumatic osteoarthritis, and it can affect both chondrocyte biomechanics and tissue health. Previously, we found that 4 weeks after anterior cruciate ligament transection (ACLT) in rabbits, proteoglycan loss was less pronounced in the pericellular matrix (PCM) than in the ...
Rasmus K. Hiltunen   +9 more
wiley   +1 more source

Novel GH115 xylan α‐1,2‐glucuronidases with distinct preferences for xylan‐derived oligomers and polymers

open access: yesProtein Science, Volume 35, Issue 5, May 2026.
Abstract Natural polymers are promising sustainable materials for diverse applications. Xylans, major components of hemicellulose, exhibit origin‐dependent substitution patterns that determine their physicochemical properties. Targeted enzymatic modification of these substituents offers a mild and precise approach for tailoring the polymer's ...
Savvina Leontakianakou   +9 more
wiley   +1 more source

Maladaptive Inflammatory Signaling in Old Mice Impairs Colonic Regeneration by Promoting a Sustained Fetal‐Like Epithelial State

open access: yesAging Cell, Volume 25, Issue 5, May 2026.
This study explores the impact of aging on regeneration of the mouse colonic epithelium. The authors find that old mice exhibit excessive and prolonged inflammation after infection with Citrobacter, resulting in the maintenance of a fetal regenerative state in epithelial cells, insufficient tissue repair, and death of the animal.
Antonion Korcari   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy