Results 21 to 30 of about 18,497 (276)
Delivery of mixed-lineage kinase domain-like protein by vapor nanobubble photoporation induces necroptotic-like cell death in tumor cells [PDF]
, 2019 Modern molecular medicine demands techniques to efficiently deliver molecules directly into mammalian cells. As proteins are the final mediators of most cellular pathways, efficient intracellular protein delivery techniques are highly desired.
Braeckmans, Kevin +10 more
core +2 more sources
Fluids and Barriers of the CNS, 2012 Background Convection-enhanced delivery (CED), a direct method for drug delivery to the brain through intraparenchymal microcatheters, is a promising strategy for intracerebral pharmacological therapy.
Barua Neil U +6 more
doaj +1 more source
Beilstein Journal of Organic Chemistry, 2015 Novel (S)-camptothecin–dextran polymers were obtained by “click” grafting of azide-modified (S)-camptothecin and alkyne-modified dextrans. Two series based on 10 kDa and 70 kDa dextrans were prepared with a degree of substitution of (S)-camptothecin ...
Thorbjørn Terndrup Nielsen +6 more
doaj +1 more source
Veins and Lymphatics, 2022 INTRODUCTION: The blood-brain barrier (BBB) is compromised in multiple central nervous system (CNS) disorders associated with neuroinflammation, including multiple sclerosis (MS).
Wenshen Wang +3 more
doaj +1 more source
Improvement of a method for the characterization of ultrafiltration membranes by measurements of tracers retention [PDF]
, 2004 The aim of this study is to improve protocols for assessing accurate characteristic retention curve and cut-off of membranes, thus enabling the manufacture and performance of the membrane to be monitored. Different data treatments are considered in order
Aimar, Pierre +3 more
core +2 more sources
Dextranas em açúcares do estado de São Paulo Dextrans in lugars from São Paulo State
Química Nova, 2008 The characterization of dextran in sugars by size exclusion chromatography (SEC) has been carried out according to the number-average molecular weight (Mn), the weight-average molecular weight (Mw), the Z-average molecular weight (Mz), and the ...
Francisco Wendel Batista de Aquino +1 more
doaj +1 more source
Dextran dextrinase and dextran of Gluconobacter oxydans
Journal of Industrial Microbiology & Biotechnology, 2005 Certain strains of Gluconobacter oxydans have been known since the 1940s to produce the enzyme dextran dextrinase (DDase; EC2.4.1.2)-a transglucosidase converting maltodextrins into (oligo)dextran. The enzyme catalyses the transfer of an alpha1,4 linked glucosyl unit from a donor to an acceptor molecule, forming an alpha1,6 linkage: consecutive ...
Myriam, Naessens +3 more
openaire +2 more sources
High and Low Molecular Weight Fluorescein Isothiocyanate (FITC)–Dextrans to Assess Blood-Brain Barrier Disruption: Technical Considerations [PDF]
, 2010 This note is to report how histological preparation techniques influence the extravasation pattern of the different molecular sizes of fluorescein isothiocyanate (FITC)-dextrans, typically used as markers for blood-brain barrier leakage.
Angelika Hoffmann +5 more
core +2 more sources
Schistosoma mansoni cercariae experience influx of macromolecules during skin penetration [PDF]
, 2009 We have observed that when cercariae penetrate the skin of mice, there is influx into their tissues of Lucifer Yellow and certain labelled molecules of up to 20 kDa molecular weight.
Coelho, P.M.Z. +5 more
core +1 more source
Aqueous Angiography with Fluorescein and Indocyanine Green in Bovine Eyes. [PDF]
, 2016 PurposeWe characterize aqueous angiography as a real-time aqueous humor outflow imaging (AHO) modality in cow eyes with two tracers of different molecular characteristics.MethodsCow enucleated eyes (n = 31) were obtained and perfused with balanced salt ...
Begian, Alan +10 more
core +3 more sources