A novel function for the Caenorhabditis elegans torsin OOC-5 in nucleoporin localization and nuclear import. [PDF]
, 2015 Torsin proteins are AAA+ ATPases that localize to the endoplasmic reticular/nuclear envelope (ER/NE) lumen. A mutation that markedly impairs torsinA function causes the CNS disorder DYT1 dystonia. Abnormalities of NE membranes have been linked to torsinA
Dauer, William T +4 more
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Schistosoma mansoni cercariae experience influx of macromolecules during skin penetration [PDF]
, 2009 We have observed that when cercariae penetrate the skin of mice, there is influx into their tissues of Lucifer Yellow and certain labelled molecules of up to 20 kDa molecular weight.
Coelho, P.M.Z. +5 more
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Influence of ultrafiltration membrane characteristics on adsorptive fouling with dextrans [PDF]
, 2005 This paper presents a detailed investigation of fouling mechanisms for ultrafiltration membranes with polysaccharides obtained by studying membrane–solute (static adsorption) and membrane–solute–solute interactions (ultrafiltration (UF)).
Susanto, H., Ulbricht, M.
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Altered Nrf2 signaling mediates hypoglycemia-induced blood-brain barrier endothelial dysfunction in vitro. [PDF]
PLoS ONE, 2015 Hypoglycemia impairs blood-brain barrier (BBB) endothelial function; a major hallmark in the pathogenesis of various CNS disorders. Previously, we have demonstrated that prolonged hypoglycemic exposure down-regulated BBB endothelial NF-E2 related factor ...
Ravi K Sajja +2 more
doaj +1 more source
Aqueous Angiography with Fluorescein and Indocyanine Green in Bovine Eyes. [PDF]
, 2016 PurposeWe characterize aqueous angiography as a real-time aqueous humor outflow imaging (AHO) modality in cow eyes with two tracers of different molecular characteristics.MethodsCow enucleated eyes (n = 31) were obtained and perfused with balanced salt ...
Begian, Alan +10 more
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Development and optimization of a novel sustained-release dextran tablet formulation for propranolol hydrochloride [PDF]
, 2006 A novel oral controlled delivery system for propranolol hydrochloride (PPL) was developed and optimized. The in vitro dissolution profiles of sustained-release matrix tablets of racemic PPL were determined and compared with the United States Pharmacopeia
Bataille, Bernard +5 more
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Microbial Cell Factories, 2019 Background Dextransucrases are extracellular enzymes, which catalyze the formation of α-1→6-linked glucose polymers from sucrose. These enzymes are exclusively expressed by lactic acid bacteria, which commonly acidify the extracellular environment due to
Jonas Schmid +3 more
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The Induction of Oxidative/Nitrosative Stress, Inflammation, and Apoptosis by a Ferric Carboxymaltose Copy Compared to Iron Sucrose in a Non-Clinical Model [PDF]
, 2015 Introduction: Ferric carboxymaltose is a next-generation polynuclear iron(III)-hydroxide carbohydrate complex for intravenous iron therapy belonging to the class of so-called non-biological complex drugs.
Angerosa, Margarita +2 more
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VH-RELATED IDIOTOPES DETECTED BY SITE-DIRECTED MUTAGENESIS [PDF]
, 1992 The function of the CD4 cell surface protein as coreceptor on T helper lymphocytes and as receptor for HIV makes this glycoprotein a prime target for an immune intervention with mAb.
Cheng, Y. H. +4 more
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Beilstein Journal of Organic Chemistry, 2015 Novel (S)-camptothecin–dextran polymers were obtained by “click” grafting of azide-modified (S)-camptothecin and alkyne-modified dextrans. Two series based on 10 kDa and 70 kDa dextrans were prepared with a degree of substitution of (S)-camptothecin ...
Thorbjørn Terndrup Nielsen +6 more
doaj +1 more source