Results 11 to 20 of about 3,806 (180)

The impact of revised definitions on the epidemiology of status epilepticus: A population-based study. [PDF]

Epilepsia
Abstract Objective Status epilepticus (SE) represents one of the most common neurological emergencies. The International League Against Epilepsy (ILAE) redefined SE duration thresholds from 30 to 5 min for convulsive SE in 2015. We conducted a prospective population‐based study to determine SE incidence and outcomes under the revised criteria and ...
Menche M, Jünemann C, Reese JP, Jünemann M, Teepker M, Best C, Roth C, Sünkeler I, Pryss E, Rosenow F, Strzelczyk A, Möller L, Habermehl L, Tsalouchidou PE, Simon O, Kemmling A, Nimsky C, Timmermann L, Menzler K, Knake S.   +19 more
europepmc   +2 more sources

Relationship of left piriform cortex network centrality with temporal lobe epilepsy duration and drug resistance. [PDF]

Eur J Neurol
Abstract Background We investigated the relationship of piriform cortex (PC) structural network centrality with drug resistance and epilepsy duration as markers of sustained epileptic activity. Methods PCs were manually delineated on retrospectively collected 3D‐T1‐MRI images of patients with temporal lobe epilepsy (TLE). Connectomes were computed from
Zahnert F, Reichert P, Linka L, Timmermann L, Kemmling A, Grote A, Nimsky C, Menzler K, Belke M, Knake S.   +9 more
europepmc   +2 more sources

Ictal Electroencephalographic Characteristics of Nodding Syndrome: A Comparative Case-Series from South Sudan, Tanzania, and Uganda. [PDF]

Ann Neurol, 2022
Nodding syndrome (NS) is a poorly understood form of childhood‐onset epilepsy that is characterized by the pathognomonic ictal phenomenon of repetitive vertical head drops. To evaluate the underlying ictal neurophysiology, ictal EEG features were evaluated in nine participants with confirmed NS from South Sudan, Tanzania, and Uganda and ictal presence ...
Mazumder R, Lagoro DK, Nariai H, Danieli A, Eliashiv D, Engel J, Dalla Bernardina B, Kegele J, Lerche H, Sejvar J, Matuja W, Schmutzhard E, Bonanni P, De Polo G, Wagner T, Winkler AS.   +15 more
europepmc   +2 more sources

Peri-ictal imaging abnormalities in non-convulsive status epilepticus: A systematic review and meta-analysis comparing magnetic resonance imaging and computed tomography perfusion. [PDF]

Epilepsia
Abstract Objective To assess and compare the detection rates of peri‐ictal abnormalities using magnetic resonance imaging (MRI) and computed tomography perfusion (CTP) in patients with non‐convulsive status epilepticus (NCSE). Methods We conducted a systematic literature search in five databases up to February 2025.
Bosque-Varela P, Kuchukhidze G, Hahn W, Jünemann C, Machegger L, Möller L, Pfaff J, Trinka E, Knake S, Tsalouchidou PE.   +9 more
europepmc   +2 more sources

Integration of interictal EEG source localization in presurgical epilepsy evaluation – A single‐center prospective study

Epilepsia Open, Volume 8, Issue 3, Page 877-887, September 2023., 2023
Abstract Objective To investigate cost in working hours for initial integration of interictal EEG source localization (ESL) into clinical practice of a tertiary epilepsy center, and to examine concordance of results obtained with three different ESL pipelines.
Gadi Miron, Thomas Baag, Kara Götz, Martin Holtkamp, Bernd J. Vorderwülbecke   +4 more
wiley   +1 more source

A novel geometry‐based analysis of hippocampal morphometry in mesial temporal lobe epilepsy

Human Brain Mapping, Volume 44, Issue 12, Page 4467-4479, 15 August 2023., 2023
Hippocampal volumetry is an essential tool in researching and diagnosing neurological diseases, such as mesial temporal lobe epilepsy. However, it is limited in its ability to detect subtle alterations in hippocampal morphometry. In this study, we establish and apply a novel geometry‐based tool that enables point‐wise morphometric analysis based on an ...
Laura Fischbach, Tobias Bauer, Kersten Diers, Juri‐Alexander Witt, Mar Brugues, Valeri Borger, Martin Schidlowski, Attila Rácz, Tobias Baumgartner, Randi von Wrede, Daniel Paech, Bernd Weber, Alexander Radbruch, Hartmut Vatter, Albert J. Becker, Hans‐Jürgen Huppertz, Christoph Helmstaedter, Rainer Surges, Martin Reuter, Theodor Rüber   +19 more
wiley   +1 more source

In vitro effects of eslicarbazepine (S‐licarbazepine) as a potential precision therapy on SCN8A variants causing neuropsychiatric disorders

British Journal of Pharmacology, Volume 180, Issue 8, Page 1038-1055, April 2023., 2023
Background and Purpose Variants in SCN8A, the NaV1.6 channel's coding gene, are characterized by a variety of symptoms, including intractable epileptic seizures, psychomotor delay, progressive cognitive decline, autistic features, ataxia or dystonia. Standard anticonvulsant treatment has a limited impact on the course of disease.
Erva Bayraktar, Yuanyuan Liu, Lukas Sonnenberg, Ulrike B. S. Hedrich, Yildirim Sara, Ahmed Eltokhi, Hang Lyu, Holger Lerche, Thomas V. Wuttke, Stephan Lauxmann   +9 more
wiley   +1 more source

The diagnostic value of ictal SPECT—A retrospective, semiquantitative monocenter study

Epilepsia Open, Volume 8, Issue 1, Page 183-192, March 2023., 2023
Abstract Objective Ictal single photon emission computed tomography (SPECT) can be used as an advanced diagnostic modality to detect the seizure onset zone in the presurgical evaluation of people with epilepsy. In addition to visual assessment (VSA) of ictal and interictal SPECT images, postprocessing methods such as ictal‐interictal SPECT analysis ...
Freya Schulte, Felix Bitzer, Florian Christoph Gärtner, Tobias Bauer, Randi von Wrede, Tobias Baumgartner, Attila Rácz, Valeri Borger, Tim von Oertzen, Hartmut Vatter, Markus Essler, Rainer Surges, Theodor Rüber   +12 more
wiley   +1 more source

Olfactory Dysfunction and Limbic Hypoactivation in Temporal Lobe Epilepsy. [PDF]

Hum Brain Mapp
This study aims to characterize olfactory function in temporal lobe epilepsy using olfactory testing and olfactory functional magnetic resonance imaging. Our findings show olfactory dysfunction associated with hypoactivation in the limbic system of people with temporal lobe epilepsy.
Schmidt M, Bauer T, Kehl M, Minarik A, Walger L, Schultz J, Otte MS, Trautner P, Hoppe C, Baumgartner T, Specht-Riemenschneider L, Mormann F, Radbruch A, Surges R, Rüber T.   +14 more
europepmc   +2 more sources

Zwischen Vielfalt und Einheit. Eine Expertenbefragung zu deutschsprachigen Zeitschriften der Erziehungswissenschaft [PDF]

, 2013
Der Beitrag stellt Ergebnisse einer mit Unterstützung der DGfE durchgeführten Studie vor, die sich mit der Frage auseinandersetzt, welche erziehungswissenschaftlichen Zeitschriften im deutschsprachigen Raum rezipiert und wie diese von Fachexperten ...
Röbken, Heinke, Zawacki-Richter, Olaf, Zierer, Klaus   +2 more
core   +1 more source