Results 41 to 50 of about 232,832 (287)

Novel DNA methylation profiles associated with key gene regulation and transcription pathways in blood and placenta of growth-restricted neonates [PDF]

, 2014
BB/H012494/1/ Biotechnology and Biological Sciences Research ...
Barg E, Bejamini Y, Chris Mathews, David J Williams, Graham A Hitman, Melissa C Smart, Robert Lowe, Sara L Hillman, Sarah Finer, Smyth GK, Vardhman K Rakyan   +10 more
core   +3 more sources

Fetal sex and the development of gestational diabetes mellitus in gravidae with multiple gestation pregnancies

Acta Obstetricia et Gynecologica Scandinavica, 2023
Introduction There is an increasing incidence of pregnancies with twin gestations. One outcome more likely to occur with multiple gestations is gestational diabetes mellitus.
Alexa M. Sassin, Haleh Sangi‐Haghpeykar, Kjersti M. Aagaard   +2 more
doaj   +1 more source

Gestational age, birth weight, and perinatal complications in mothers with diabetes and impaired glucose tolerance: Japan Environment and Children's Study cohort.

PLoS ONE, 2022
We aimed to determine the risk of perinatal complications during delivery in mothers with non-normal glucose tolerance in a large Japanese birth cohort. We analysed data of 24,295 neonate-mother pairs in the Japan Environment and Children's Study cohort ...
Hiroshi Yokomichi, Mie Mochizuki, Ryoji Shinohara, Megumi Kushima, Sayaka Horiuchi, Reiji Kojima, Tadao Ooka, Yuka Akiyama, Kunio Miyake, Sanae Otawa, Zentaro Yamagata, Japan Environment and Children’s Study Group   +11 more
doaj   +3 more sources

Risk Factors for Gestational Diabetes in Women with Polycystic Ovarian Syndrome

Medicine Science, 2016
We aimed to compare the pre-gestational metabolic states of the women who were previously diagnosed with policystic ovarian syndrome and had gestational diabetes mellitus in the subsequent pregnancy and who did not have gestational diabetes mellitus in ...
Senem Arda Duz, Ilgin Turkcuoglu
doaj   +1 more source

The diversity of trophoblast cells and niches of placenta accreta spectrum disorders revealed by single-cell RNA sequencing

Frontiers in Cell and Developmental Biology, 2022
Placenta accreta spectrum disorders (PAS) are severe pregnancy complications that occur when extravillous trophoblast cells (EVTs) invade beyond the uterine inner myometrium and are characterized by hypervascularity on prenatal ultrasound and ...
Jingmei Ma, Jingmei Ma, Jingmei Ma, Yawei Liu, Yawei Liu, Yawei Liu, Yawei Liu, Yawei Liu, Zhirong Guo, Zhirong Guo, Run Sun, Run Sun, Run Sun, Run Sun, Xinrui Yang, Xinrui Yang, Weiran Zheng, Weiran Zheng, Yongdan Ma, Yongdan Ma, Yin Rong, Yin Rong, Yin Rong, Yin Rong, Hongmei Wang, Hongmei Wang, Hongmei Wang, Hongmei Wang, Huixia Yang, Huixia Yang, Zhenyu Xiao, Zhenyu Xiao, Zhenyu Xiao, Zhenyu Xiao, Zhenyu Xiao   +34 more
doaj   +1 more source

Proteomic analyses of Urine Exosomes reveal New Biomarkers of Diabetes in Pregnancy. [PDF]

, 2016
ObjectiveTo evaluate 24 hour urine exosome protein content changes among pregnant US subjects with diabetes and obesity during early pregnancy.MethodsThe exosome proteome content from 24 hour urine samples of pregnant subjects with gestational diabetes ...
Aghania, Eamon, Awdishu, Linda, Bounkhoun, Anousone, Ghassemian, Majid, Hamlin, Alyssa A, Ishaya, Michelle, Kao, Kelly, Khoshaba, Roni, Kokoy-Mondragon, Chanthel, Madrigal, Assael, Naviaux, Robert K, Overcash, Rachael, Proudfoot, James, Ramachandrarao, Satish P, Tarsa, Maryam, Zhou, Marcela   +15 more
core  

Mediation Analysis Supports a Causal Relationship between Maternal Hyperglycemia and Placental DNA Methylation Variations at the Leptin Gene Locus and Cord Blood Leptin Levels. [PDF]

, 2020
Changes in fetal DNA methylation (DNAm) of the leptin (LEP) gene have been associated with exposure to maternal hyperglycemia, but their links with childhood obesity risk are still unclear.
Bouchard, Luigi, Breton, Edith, Cardenas, Andres, Fortin, Carol-Ann, Gagné-Ouellet, Valérie, Guérin, Renée, Hivert, Marie-France, Perron, Patrice, Thibeault, Kathrine   +8 more
core   +1 more source

Human Endometrial Extracellular Matrix Hydrogel Facilitated Endometrial Mesenchymal Stem Cells for Endometrial Regeneration

Advanced Healthcare Materials, EarlyView.
Adequate thickness of the uterine lining is crucial for women with thin or damaged endometrium to achieve pregnancies. Endometrial mesenchymal stem cells (eMSC) can facilitate the cyclical repair and regeneration of the human endometrium. In this study, the human endometrium derived extracellular matrix hydrogel supports the growth of eMSC promoting ...
Jingwen Xu, Philip C N Chiu, Ernest H Y Ng, Sentao Hu, Zi Ye, Liaobing Xin, Lie Ma, Songying Zhang, William S B Yeung, Rachel W S Chan   +9 more
wiley   +1 more source

Treatments for gestational diabetes [PDF]

Cochrane Database of Systematic Reviews, 2009
Gestational diabetes (GDM) affects 3% to 6% of all pregnancies. Women are often intensively managed with increased obstetric monitoring, dietary regulation, and insulin. However, there has been no sound evidence base to support intensive treatment. The key issue for clinicians and consumers is whether treatment of GDM improves perinatal outcome.To ...
Alwan, Nisreen, Tuffnell, Derek J., West, Jane   +2 more
openaire   +3 more sources

New Insights into Atonic Postpartum Hemorrhage: Animal Model Construction Based on Placental Nanodelivery Systems

Advanced Healthcare Materials, EarlyView.
This study develops a placenta‐targeted nanodelivery system co‐loading HMGB1 protein and the NLRP3 agonist nigericin to establish an animal model of atonic postpartum hemorrhage. The model accurately recapitulates clinical phenotypes, including prolonged labor and uterine contractility dysfunction, while revealing inflammatory activation in placental ...
Jiangxue Qu, Ruiqi Wu, Hai Jiang, Lian Chen, Yingying Tian, Shuai Zeng, Tongmin Liu, Cheng Zhao, Huifeng Shi, Xiaolong Liang, Yangyu Zhao   +10 more
wiley   +1 more source