Results 61 to 70 of about 1,595,796 (305)

Gestational diabetes mellitus: Association with maternal and neonatal complications [PDF]

, 2023
Background and objectives: Gestational diabetes mellitus (GDM) is known to be associated with pregnancy complications but there is limited evidence about the strength of these associations in recent clinical practice, especially after the introduction of
Akolekar, R., Giacchino, T., Ramadan, G., Karkia, R., Shah, Saadia, Gough, Andrew, Andrew Gough, Ranjit Akolekar, Rebecca Karkia, Ghada Ramadan, Tara Giacchino, Saadia Shah   +11 more
core   +1 more source

A Rare Form of Microcephalic Primordial Dwarfism due to NSMCE2 Deficiency (Seckel Syndrome Type 10): A Report of Macular Involvement

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Biallelic variants in NSMCE2 (MMS21), which encodes the SUMO E3 ligase subunit of the SMC5/6 chromatin‐maintenance complex, have recently been implicated in microcephalic primordial dwarfism (MPD), corresponding to Seckel syndrome type 10 (OMIM #617246).
Cristina Peduto, Céline Huber, Clément Paya, Isabelle Audo, Nathalie Boddaert, Valérie Cormier‐Daire   +5 more
wiley   +1 more source

Gestational Diabetes [PDF]

What Is It? Gestational diabetes (GDM) is the most common problem of pregnancy. It affects about 4 percent of all pregnancies. GDM occurs when the blood sugar (glucose) is higher than normal during pregnancy. Depending on risk factors, a woman may or may

core   +2 more sources

Maternal and neonatal outcomes of gestational diabetes: A retrospective cohort study from Southern India

Journal of Family Medicine and Primary Care, 2015
Background: The prevalence of gestational diabetes is on the rise. Understanding the various outcomes of it is necessary to face this challenge. Objectives: To study the frequency of occurrence of various maternal and fetal outcomes among gestational ...
P R Sreelakshmi, Sanjeev Nair, Biju Soman, Rani Alex, K Vijayakumar, V Raman Kutty   +5 more
doaj   +1 more source

TDAG51 Attenuates Impaired Lipid Metabolism and Insulin Resistance in Gestational Diabetes Mellitus Through SREBP-1/ANGPTL8 Pathway

Balkan Medical Journal, 2023
Background: T-cell death-associated gene 51 (TDAG51) belongs to the transcription factor family and is involved in the energy homeostasis of the liver through the regulation of lipogenesis.
Xiaozhi Wu, Biru Xiao
doaj   +1 more source

Biallelic PAX6 Variants in an Adult With Severe Microphthalmia and Preserved Intellectual Function

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT PAX6 encodes a dosage‐sensitive transcription factor that is essential for eye development. Heterozygous PAX6 disease is well characterized, but biallelic disease is extremely rare and has been associated with anophthalmia, severe brain malformations, and perinatal lethality.
Karl De Geer, Britt‐Marie Anderlid, Lena Jacobson, Daniel Martín Muñoz, Erik Björck   +4 more
wiley   +1 more source

Costs and consequences of treatment for mild gestational diabetes mellitus - evaluation from the ACHOIS randomised trial [PDF]

, 2007
Background: Recommended best practice is that economic evaluation of health care interventions should be integral with randomised clinical trials. We performed a cost-consequence analysis of treating women with mild gestational diabetes mellitus by ...
Hiller, J., Hiller Janet E, Crowther Caroline A, Moss, J., Jeffrey S Robinson, Caroline A Crowther, null null, Crowther, C., Janet E Hiller, Willson, K., Robinson, J., Moss John R, John R Moss, Willson Kristyn J, Kristyn J Willson, Robinson Jeffrey S   +15 more
core   +2 more sources

Treatments for gestational diabetes [PDF]

Cochrane Database of Systematic Reviews, 2009
Gestational diabetes (GDM) affects 3% to 6% of all pregnancies. Women are often intensively managed with increased obstetric monitoring, dietary regulation, and insulin. However, there has been no sound evidence base to support intensive treatment. The key issue for clinicians and consumers is whether treatment of GDM improves perinatal outcome.To ...
Alwan, Nisreen, Tuffnell, Derek J., West, Jane   +2 more
openaire   +3 more sources

Maternal Factors Modifying the Link Between Genetic Risk for Autism and Developmental Milestones

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Although common genetic liability—quantified through polygenic risk scores (PRS)—accounts for substantial variance in autism spectrum disorder (ASD) liability, how prenatal environmental exposures interact with genetic predisposition to shape developmental outcomes remains poorly understood. Using the data from Autism Genetic Resource Exchange
Liliana D'Alesio, Vishani Nimish Patel, McKenna Walsh, Erick Messias, Ping‐I Lin   +4 more
wiley   +1 more source

Lifestyle interventions for overweight and obese pregnant women to improve pregnancy outcome: systematic review and meta-analysis [PDF]

, 2012
BACKGROUND: Overweight and obesity pose a big challenge to pregnancy as they are associated with adverse maternal and perinatal outcome. Evidence of lifestyle intervention resulting in improved pregnancy outcome is conflicting.
Croker, H, Varma, Rajesh, Oteng-Ntim, Eugene, Poston, Lucilla, Helen Croker, Poston, L, Doyle, P, Lucilla Poston, Rajesh Varma, Oteng-Ntim, E, Varma, R, Croker, Helen, Doyle, Pat, Eugene Oteng-Ntim, Pat Doyle, Poston, Lucilla; id_orcid   +15 more
core   +2 more sources