What Is Gestational Diabetes? [PDF]
Gestational diabetes mellitus (GDM) is defined as glucose intolerance with onset or first recognition during pregnancy. As such, GDM is the product of routine glucose tolerance screening that is currently carried out in otherwise healthy individuals.
Thomas A, Buchanan +3 more
openaire +2 more sources
EPIDEMIOLOGY AND PREVALENCE OF GESTATIONAL DIABETES MELLITUS [PDF]
Type 2 diabetes mellitus is increasing rapidly all over the world. Women of childbearing age are also affected by obesity and sedentary lifestyle, which are the main causes of this increase. In recent years, epidemiological studies in developed countries
Karakiliç, Ersen
core
Pre-pregnancy care for women with pre-gestational diabetes mellitus : a systematic review and meta-analysis [PDF]
Background Pre-gestational diabetes mellitus is associated with increased risk for maternal and fetal adverse outcomes. This systematic review was carried out to evaluate the effectiveness and safety of pre-pregnancy care in improving the rate of ...
Samia A Esmaeil +5 more
core +1 more source
Sex‐Specific Regulation of Glycemic Homeostasis by Theabrownin from Pu‐erh Tea
Pu‐erh tea's key component, theabrownin (TB), lowers blood glucose in a sex‐specific manner. In females, estrogen boosts intestinal MUC2 production, which dramatically enhances TB's ability to inhibit the carbohydrate‐digesting enzyme α‐glucosidase.
Yang Li +22 more
wiley +1 more source
The Prevalence of Gestational Diabetes [PDF]
Gestational diabetes mellitus (GDM) is defined as a glucose tolerance disorder that arises during pregnancy. Estimates of its prevalence vary widely because of varying threshold values. Screening of all pregnant women with a two-step test has been available in Germany since 2012.
Hanne, Melchior +2 more
openaire +2 more sources
Lifestyle interventions for overweight and obese pregnant women to improve pregnancy outcome: systematic review and meta-analysis [PDF]
BACKGROUND: Overweight and obesity pose a big challenge to pregnancy as they are associated with adverse maternal and perinatal outcome. Evidence of lifestyle intervention resulting in improved pregnancy outcome is conflicting.
Croker, H +15 more
core +1 more source
G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang +9 more
wiley +1 more source
Costs and consequences of treatment for mild gestational diabetes mellitus - evaluation from the ACHOIS randomised trial [PDF]
Background: Recommended best practice is that economic evaluation of health care interventions should be integral with randomised clinical trials. We performed a cost-consequence analysis of treating women with mild gestational diabetes mellitus by ...
Hiller, J. +15 more
core +1 more source
Targeting Supramolecular Active Complexes of Nav1.7/Nav1.8 to Relieve Chronic Neuropathic Pain
In mice and patients with severe chronic neuropathic pain (NP), Nav1.7, Nav1.8, TrkB, and five cytoskeletal proteins form supramolecular active complexes (SMACs) with polygonal lattice structures as noxious signal amplifiers in dorsal root ganglion (DRG) neurons.
Liting Sun +27 more
wiley +1 more source
Treatments for gestational diabetes [PDF]
Gestational diabetes (GDM) affects 3% to 6% of all pregnancies. Women are often intensively managed with increased obstetric monitoring, dietary regulation, and insulin. However, there has been no sound evidence base to support intensive treatment. The key issue for clinicians and consumers is whether treatment of GDM improves perinatal outcome.To ...
Alwan, Nisreen +2 more
openaire +3 more sources

