Results 161 to 170 of about 67,953 (211)

Oxidative stress and diabetes: antioxidative strategies

Frontiers of Medicine, 2020
Diabetes mellitus is one of the major public health problems worldwide. Considerable recent evidence suggests that the cellular reduction-oxidation (redox) imbalance leads to oxidative stress and subsequent occurrence and development of diabetes and related complications by regulating certain signaling pathways involved in β-cell dysfunction and ...
Pengju, Zhang   +5 more
openaire   +2 more sources

Diabetes, oxidative stress, and antioxidants: A review

Journal of Biochemical and Molecular Toxicology, 2003
AbstractIncreasing evidence in both experimental and clinical studies suggests that oxidative stress plays a major role in the pathogenesis of both types of diabetes mellitus. Free radicals are formed disproportionately in diabetes by glucose oxidation, nonenzymatic glycation of proteins, and the subsequent oxidative degradation of glycated proteins ...
A C, Maritim, R A, Sanders, J B, Watkins
openaire   +2 more sources

Oxidative Stress and Antioxidant Treatment in Diabetes

Annals of the New York Academy of Sciences, 2004
Abstract: The many studies on oxidative stress, antioxidant treatment, and diabetic complications have shown that oxidative stress is increased and may accelerate the development of complications through the metabolism of excessive glucose and free fatty acids in diabetic and insulin‐resistant states.
Joshua A, Scott, George L, King
openaire   +2 more sources

Oxidative Stress in Preretinopathic Diabetes Subjects and Antioxidants

Diabetes Technology & Therapeutics, 2012
This study assessed the effect of a systemic oral treatment with antioxidants (AOs) in preretinopathic diabetes (PRD) patients, through the evaluation of oxidative stress in plasma and changes in the full-field electroretinogram (ERG).Thirty-two PRD subjects with good metabolic control were recruited.
NEBBIOSO, Marcella   +4 more
openaire   +3 more sources

Diabetic Cardiomyopathy and Oxidative Stress: Role of Antioxidants

Cardiovascular & Hematological Agents in Medicinal Chemistry, 2011
Diabetes has emerged as a major threat to worldwide health. The increasing incidence of diabetes in young individuals is particularly worrisome given that the disease is likely to evolve over a period of years. In 1972, the existence of a diabetic cardiomyopathy was proposed based on the experience with four adult diabetic patients who suffered from ...
Rajarajan A, Thandavarayan   +3 more
openaire   +2 more sources

A discussion of diabetes, antioxidants and oxidative stress

Asian Journal of Multidimensional Research, 2021
Oxidative stress seems to have a significant role in the development of both forms of diabetes mellitus, according to a growing body of data from both potential therapeutic investigations. In diabetes, glucose oxidation, non-enzymatic glycation of proteins, and subsequent oxidative breakdown of fasting blood glucose proteins produce a disproportionate ...
openaire   +1 more source

Role of oxidative stress in diabetes-induced complications and their management with antioxidants

Archives of Physiology and Biochemistry, 2023
Diabetes mellitus (DM) is a huge global health issue and one of the most studied diseases, with a large global prevalence. Oxidative stress is a cytotoxic consequence of the excessive development of ROS and suppression of the antioxidant defense system for ROS elimination, which accelerates the progression of diabetes complications such as diabetic ...
Hasandeep, Singh   +6 more
openaire   +2 more sources

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