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Targeting oxidative stress through antioxidants in diabetes mellitus
Journal of Drug Targeting, 2018The myriad of complications associated with diabetes is closely linked with the generation of reactive species or free radicals leading to oxidative and nitrosative stress. Increased oxidative stress is an important cause and result of diabetes and it is thought to underlie the cellular changes that lead to diabetic complications.
Parul Thakur +2 more
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Effect of haemodialysis on the oxidative stress and antioxidants in diabetes mellitus
Acta Diabetologica, 2005Oxidative stress has been defined as a loss of counterbalance between free radical or reactive oxygen species (ROS) production and antioxidant systems. It is involved in the pathogenesis of different chronic diseases. High levels of ROS production via different biochemical mechanisms accompany diseases like type 2 diabetes mellitus (DM) and end-stage ...
E, Dursun +3 more
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ANTIOXIDANTS AND OXIDATIVE STRESS IN DIABETES MELLITUS
2023The frequency of diabetes mellitus, a common metabolic condition, has significantly increased among adults worldwide. Based on projections, there might be a significant increase to 30 million cases by 2025, which is a concerning rise from 135 million cases in 1995.
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The Role of Antioxidants on Oxidative Stress in Diabetes Mellitus
Journal of Pharmacy Technology, 2010Objective: To evaluate the literature on the role of oxidative stress in diabetes mellitus and search sources of promising antioxidants: pharmaceutical, dietary supplements, or investigational compounds. Data Sources: A preliminary ...
Lunawati L Bennett, Teresa Seefeldt
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Oxidative stress and antioxidant treatment in diabetic neuropathy
Neuroscience Research Communications, 1997Oxidative stress is one of the factors contributing to the development of diabetic neuropathy. Several mechanisms, among which glucose autooxidation, glycation of antioxidant enzymes like superoxide dismutase, catalase and glutathione peroxidase, and increased polyol pathway activity, lead to increased production of reactive oxygen species. Both direct
P. Sytze Van Dam, Bert Bravenboer
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The Roles of Oxidative Stress and Antioxidant Treatment in Experimental Diabetic Neuropathy
Diabetes, 1997Oxidative stress is present in the diabetic state. Our work has focused on its presence in peripheral nerves. Antioxidant enzymes are reduced in peripheral nerves and are further reduced in diabetic nerves. That lipid peroxidation will cause neuropathy is supported by evidence of the development of neuropathy de novo when normal nerves are rendered α ...
P A, Low +2 more
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Journal of Investigative Medicine, 2004
The diabetic state confers an increased propensity to accelerated atherogenesis. In addition to the established risk factors, there is evidence for increased oxidative stress in diabetes. Increased oxidative stress is manifested by increased lipid peroxidation, increased F 2 -isoprostanes ...
Sonia, Vega-López +2 more
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The diabetic state confers an increased propensity to accelerated atherogenesis. In addition to the established risk factors, there is evidence for increased oxidative stress in diabetes. Increased oxidative stress is manifested by increased lipid peroxidation, increased F 2 -isoprostanes ...
Sonia, Vega-López +2 more
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Oxidative stress and antioxidant status in type 1 diabetes mellitus
Journal of Internal Medicine, 2002Abstract. Vessby J, Basu S, Mohsen R, Berne C, Vessby B (Section for Clinical Nutrition Research, Department of Public and Caring Sciences; and Department of Internal Medicine, Uppsala University, Uppsala, Sweden). Oxidative stress and antioxidant status in type 1 diabetes mellitus. J Intern Med 2002; 251: 69–76. Objectives.
J, Vessby +4 more
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Oxidative Stress and Antioxidants in Type 2 Diabetes
2001Diabetes mellitus is a leading cause of morbidity and mortality mostly because of its vascular complications (1,2). Diabetic complications can be broadly classified into microvascular (retinopathy, nephropathy) and macrovascular (coronary artery disease [CAD], cerebrovascular disease, peripheral vascular disease).
Srideri Devaraj, Ishwarlal Jialal
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The Role of Dietary Antioxidants on Oxidative Stress in Diabetic Nephropathy.
Iranian journal of kidney diseases, 2021Diabetic nephropathy (ND) is the leading cause of end-stage renal disease and oxidative stress (OS) has been recognized as a key factor in the pathogenesis and progression. Hyperglycemia, reactive oxygen species, advanced glycation end products, arterial pressure, insulin resistance, decrease in nitric oxide, inflammatory markers, and cytokines, among ...
Francisco, Gerardo Yanowsky-Escatell +7 more
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