Characterization of human bone marrow derived mesenchymal stem cells as a model for in vitro adipocytes studies [PDF]
Overweight and obesity are major problems of public health in many countries worldwide. Overweight can cause severe diseases such as type II diabetes mellitus, hypertension, stroke, heart failure and several types of cancer.
Hirzel, Estelle
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Oxidative Stress‐Related Mechanisms and Antioxidant Therapy in Diabetic Retinopathy [PDF]
Diabetic retinopathy (DR) is one of the most common microvascular complications of diabetes and is the leading cause of blindness in young adults. Oxidative stress has been implicated as a critical cause of DR. Metabolic abnormalities induced by high‐glucose levels are involved in the development of DR and appear to be influenced by oxidative stress ...
Cheng Li +6 more
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Diabetes and thrombosis: a central role for vascular oxidative stress [PDF]
Diabetes mellitus is the fifth most common cause of death worldwide. Due to its chronic nature, diabetes is a debilitating disease for the patient and a relevant cost for the national health system.
Vaidya, Aishwarya R. +11 more
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Impact of antioxidants on seminal vesicles function and fertilizing potential in diabetic rats
Diabetes mellitus significantly affects the male reproduction and sexual function. In the present study, we investigated the diabetes-induced dysfunction of seminal vesicles (SVs) in the diabetes-rat model and the role of antioxidants.
Panagiota Tsounapi +8 more
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The Role of Oxidative Stress and Antioxidants in Diabetic Complications
Diabetes is considered to be one of the most common chronic diseases worldwide. There is a growing scientific and public interest in connecting oxidative stress with a variety of pathological conditions including diabetes mellitus (DM) as well as other human diseases. Previous experimental and clinical studies report that oxidative stress plays a major
Fatmah A Matough +4 more
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Oxidative stress stimulates alpha-tocopherol transfer protein in human trophoblast tumor cells BeWo [PDF]
alpha-Tocopherol transfer protein (alpha-TTP) has been identified as the major intracellular transport protein for the antioxidant vitamin E (alpha-Tocopherol).
Etzl, Ronny P. +7 more
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Clinical Relevance of lncRNA and Mitochondrial Targeted Antioxidants as Therapeutic Options in Regulating Oxidative Stress and Mitochondrial Function in Vascular Complications of Diabetes [PDF]
Metabolic imbalances and persistent hyperglycemia are widely recognized as driving forces for augmented cytosolic and mitochondrial reactive oxygen species (ROS) in diabetes mellitus (DM), fostering the development of vascular complications such as ...
Zeljko J. Bosnjak +3 more
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Nutraceuticals against Oxidative Stress in Autoimmune Disorders [PDF]
Antioxidant mechanisms are constituted of enzymes, endogenous, and non-enzymatic, exogenous, which have the role of counterbalancing oxidative stress. Intake of these compounds occurs in the diet.
Michele Navarra +8 more
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Super power of antioxidant in oxidative stress and Diabetes Mellitus [PDF]
Diabetes mellitus is a group of metabolic disorder characterized by peculiarly high levels of blood glucose due to complete or relative insufficiency of insulin secretion as well as disturbances in carbohydrate, fat and protein metabolism. Increasing indication revealed that oxidative stress plays a main role in the pathogenesis of ...
Mariyam S, Jose J, Kumar S, Parmar MY
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Redox Balance in Type 2 Diabetes: Therapeutic Potential and the Challenge of Antioxidant-Based Therapy [PDF]
Oxidative stress is an important factor in the development of type 2 diabetes (T2D) and associated complications. Unfortunately, most clinical studies have failed to provide sufficient evidence regarding the benefits of antioxidants (AOXs) in treating ...
Tovit Rosenzweig, Lital Argaev-Frenkel
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