An update on diabetic kidney disease, oxidative stress and antioxidant agents [PDF]
Journal of Renal Injury Prevention, 2017 Diabetes mellitus is a metabolic disease that is defined by relative or absolute deficiency of insulin secretion. Diabetic kidney disease seems to be one of the most frequent complications of diabetes mellitus. Based on evidence, increased free-radical formation and/or diminished antioxidant defenses induce oxidative stress that is implicated in the ...
Mahmoodnia, Leila +3 more
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Bioactive Compounds in Oxidative Stress-Mediated Diseases: Targeting the NRF2/ARE Signaling Pathway and Epigenetic Regulation [PDF]
, 2021 Oxidative stress is a pathological condition occurring due to an imbalance between the oxidants and antioxidant defense systems in the body. Nuclear factor E2-related factor 2 (NRF2), encoded by the gene NFE2L2, is the master regulator of phase II ...
Joohyun Lee +11 more
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Oxygen, 2022 The rising prevalence of chronic metabolic disorders, such as obesity and type 2 diabetes, most notably associated with cardiovascular diseases, has emerged as a major global health concern.
Yi Tan, Meng Sam Cheong, Wai San Cheang
doaj +1 more source
Antioxidants and Oxidative Stress in Diabetes
, 2018 Oxidative stress occurs when there is a disturbance in the balance between production of reactive oxygen species and antioxidant defense system. Reactive oxygen species are radicals such as superoxide and hydroxyl while non radical reactive oxygen species are hydrogen peroxide, hypochlorite and singlet oxygen.
Ibiene Sarah Kalio, Tamunoemine Davis
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Erythrocyte oxidative stress in clinical management of diabetes and its cardiovascular complications [PDF]
, 2007 Diabetes mellitus is a chronic disease in its own right and is also regarded as a cardiovascular risk factor as well as a cardiovascular disease, due to its ability to progress to a stage of cardiovascular co-morbidity.
Jelinek, H. F. +3 more
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Portulaca Oleracea L. (Purslane) Extract Protects Endothelial Function by Reducing Endoplasmic Reticulum Stress and Oxidative Stress through AMPK Activation in Diabetic Obese Mice [PDF]
, 2023 Portulaca oleracea L. (purslane) is a food and a traditional drug worldwide. It exhibits anti-inflammatory, anti-oxidative, anti-tumor, and anti-diabetic bioactivities; but its activity on diabetic-associated endothelial dysfunction is unknown.
Chunxiu Zhou +8 more
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Molecules, 2012 The global prevalence of chronic diseases such as diabetes mellitus, hypertension, atherosclerosis, cancer and Alzheimer's disease is on the rise. These diseases, which constitute the major causes of death globally, are associated with oxidative stress ...
Mohd S. Ab Wahab +2 more
doaj +1 more source
Effects of Apocynin on Heart Muscle Oxidative Stress of Rats with Experimental Diabetes: Implications for Mitochondria [PDF]
, 2021 Diabetes mellitus (DM) constitutes one of the public health problems today. It is characterized by hyperglycemia through a defect in the β-cells function and/or decreased insulin sensitivity.
Sarai Sánchez-Duarte +5 more
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International Journal of Plant Based Pharmaceuticals, 2023 Diabetic nephropathy (DN) has become an utmost reason for long-standing renal dysfunction and end-stage renal disease globally. Oxidative stress induced by persistent hyperglycemia is considered a fundamental element in the evolution of DN.
Pooja B. Rasal +4 more
doaj +1 more source
Oxidative Stress and Cardiovascular Risk Factors: The Coronary Artery Risk Development in Young Adults (CARDIA) Study [PDF]
, 2023 Introduction—Oxidative stress is linked to cardiovascular diseases (CVD) and is suggested to vary by sex. However, few population-level studies have explored these associations and the majority comprise populations with advanced CVD.
James M. Shikany +16 more
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