Results 1 to 10 of about 4,015,617 (418)

Cardiovascular Autonomic Neuropathy in Type 1 Diabetes Is Associated With Disturbances in TCA, Lipid, and Glucose Metabolism

open access: yesFrontiers in Endocrinology, 2022
IntroductionDiabetic cardiovascular autonomic neuropathy (CAN) is associated with increased mortality and morbidity. To explore metabolic mechanisms associated with CAN we investigated associations between serum metabolites and CAN in persons with type 1
Christian S. Hansen   +14 more
doaj   +1 more source

Novel topical allogeneic bone-marrow-derived mesenchymal stem cell treatment of hard-to-heal diabetic foot ulcers: a proof of concept study

open access: yesStem Cell Research & Therapy, 2022
Aim The aim of this study was to investigate safety of treating diabetic foot ulcers with a topically administered mesenchymal stem cell product. Method Individuals with diabetes, peripheral neuropathy, toe blood pressure > 39 mmHg and non-infected foot ...
Jonas Askø Andersen   +7 more
doaj   +1 more source

Complications of Diabetes [PDF]

open access: yesJournal of Diabetes Research, 2015
Diabetes is justly recognized as an emerging global epidemic, representing one of the leading causes of morbidity and mortality worldwide. Hyperglycemia, the common characteristic of both type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM), has the potential to cause serious complications due to its insidious and chronic nature.
Konstantinos Papatheodorou   +4 more
openaire   +4 more sources

Important Drop in Rate of Acute Diabetes Complications in People With Type 1 or Type 2 Diabetes After Initiation of Flash Glucose Monitoring in France: The RELIEF Study

open access: yesDiabetes Care, 2021
OBJECTIVE The RELIEF study assessed rates of hospitalization for acute diabetes complications in France before and after initiation of the FreeStyle Libre system.
R. Roussel   +7 more
semanticscholar   +1 more source

Angiotensin II-Induced Long Non-Coding RNA Alivec Regulates Chondrogenesis in Vascular Smooth Muscle Cells

open access: yesCells, 2021
Long non-coding RNAs (lncRNAs) play key roles in Angiotensin II (AngII) signaling but their role in chondrogenic transformation of vascular smooth muscle cells (VSMCs) is unknown.
Vishnu Amaram Samara   +9 more
doaj   +1 more source

Sestrin2 in diabetes and diabetic complications

open access: yesFrontiers in Endocrinology, 2023
Diabetes is a global health problem which is accompanied with multi-systemic complications. It is of great significance to elucidate the pathogenesis and to identify novel therapies of diabetes and diabetic complications. Sestrin2, a stress-inducible protein, is primarily involved in cellular responses to various stresses.
Xiaodan Zhang   +5 more
openaire   +3 more sources

miR-379 deletion ameliorates features of diabetic kidney disease by enhancing adaptive mitophagy via FIS1

open access: yesCommunications Biology, 2021
Kato, Abdollahi et al. identify a redox protein thioredoxin and mitochondrial fission-1 (FIS1) protein as miR-379 targets in mouse kidney. They find that miR-379 knockout mice are protected from diabetic kidney disease by enhancing mitophagy via FIS1 ...
Mitsuo Kato   +14 more
doaj   +1 more source

Cardiovascular characterisation of a novel mouse model that combines hypertension and diabetes co-morbidities

open access: yesScientific Reports, 2023
Epidemiologic data suggest that the prevalence of hypertension in patients with diabetes mellitus is ∼1.5–2.0 times greater than in matched non-diabetic patients.
Arpeeta Sharma   +10 more
doaj   +1 more source

The effect of liraglutide and sitagliptin on oxidative stress in persons with type 2 diabetes

open access: yesScientific Reports, 2021
Glucagon-like peptide 1 receptor agonists have shown cardioprotective effects which have been suggested to be mediated through inhibition of oxidative stress.
Suvanjaa Sivalingam   +14 more
doaj   +1 more source

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