Results 1 to 10 of about 1,073,655 (357)

Prevalence and impact of sociodemographic factors, comorbidities, and lifestyle on diabetes complications among patients with type 2 diabetes in Riyadh. [PDF]

Sci Rep
AlOmeir O, Almuqbil M, Alotaibi NF, Alotaibi FRN, Alnazer WR, Alenazi LK, Alotaibi FN, Otaif HA, Alsanie WF, Alamri AS, Alhomrani M, Alshammary AF, Asdaq SMB.   +12 more
europepmc   +3 more sources

Inflammation in diabetes complications: molecular mechanisms and therapeutic interventions. [PDF]

MedComm (2020)
Zhao L, Hu H, Zhang L, Liu Z, Huang Y, Liu Q, Jin L, Zhu M, Zhang L.   +8 more
europepmc   +3 more sources

Cardiovascular Autonomic Neuropathy in Type 1 Diabetes Is Associated With Disturbances in TCA, Lipid, and Glucose Metabolism

Frontiers in Endocrinology, 2022
IntroductionDiabetic cardiovascular autonomic neuropathy (CAN) is associated with increased mortality and morbidity. To explore metabolic mechanisms associated with CAN we investigated associations between serum metabolites and CAN in persons with type 1
Christian S. Hansen, Tommi Suvitaival, Simone Theilade, Simone Theilade, Simone Theilade, Ismo Mattila, Maria Lajer, Kajetan Trošt, Linda Ahonen, Tine W. Hansen, Cristina Legido-Quigley, Peter Rossing, Peter Rossing, Tarunveer S. Ahluwalia, Tarunveer S. Ahluwalia   +14 more
doaj   +1 more source

Novel topical allogeneic bone-marrow-derived mesenchymal stem cell treatment of hard-to-heal diabetic foot ulcers: a proof of concept study

Stem Cell Research & Therapy, 2022
Aim The aim of this study was to investigate safety of treating diabetic foot ulcers with a topically administered mesenchymal stem cell product. Method Individuals with diabetes, peripheral neuropathy, toe blood pressure > 39 mmHg and non-infected foot ...
Jonas Askø Andersen, Anne Rasmussen, Marie Frimodt-Møller, Susanne Engberg, Esther Steeneveld, Klaus Kirketerp-Møller, Timothy O’Brien, Peter Rossing   +7 more
doaj   +1 more source

Angiotensin II-Induced Long Non-Coding RNA Alivec Regulates Chondrogenesis in Vascular Smooth Muscle Cells

Cells, 2021
Long non-coding RNAs (lncRNAs) play key roles in Angiotensin II (AngII) signaling but their role in chondrogenic transformation of vascular smooth muscle cells (VSMCs) is unknown.
Vishnu Amaram Samara, Sadhan Das, Marpadga A. Reddy, Vinay Singh Tanwar, Kenneth Stapleton, Amy Leung, Maryam Abdollahi, Rituparna Ganguly, Linda Lanting, Rama Natarajan   +9 more
doaj   +1 more source

Sestrin2 in diabetes and diabetic complications

Frontiers in Endocrinology, 2023
Diabetes is a global health problem which is accompanied with multi-systemic complications. It is of great significance to elucidate the pathogenesis and to identify novel therapies of diabetes and diabetic complications. Sestrin2, a stress-inducible protein, is primarily involved in cellular responses to various stresses.
Xiaodan Zhang, Zirui Luo, Jiahong Li, Yaxuan Lin, Yu Li, Wangen Li   +5 more
openaire   +3 more sources

Shared signaling pathways and comprehensive therapeutic approaches among diabetes complications. [PDF]

Front Med (Lausanne)
Ebrahimi M, Ahmadieh H, Rezaei Kanavi M, Safi S, Alipour-Parsa S, Advani S, Sorenson CM, Sheibani N.   +7 more
europepmc   +3 more sources

Complications of Diabetes [PDF]

Journal of Diabetes Research, 2015
Diabetes is justly recognized as an emerging global epidemic, representing one of the leading causes of morbidity and mortality worldwide. Hyperglycemia, the common characteristic of both type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM), has the potential to cause serious complications due to its insidious and chronic nature.
Konstantinos Papatheodorou, Maciej Banach, Michael Edmonds, Nikolaos Papanas, Dimitrios Papazoglou   +4 more
openaire   +3 more sources

miR-379 deletion ameliorates features of diabetic kidney disease by enhancing adaptive mitophagy via FIS1

Communications Biology, 2021
Kato, Abdollahi et al. identify a redox protein thioredoxin and mitochondrial fission-1 (FIS1) protein as miR-379 targets in mouse kidney. They find that miR-379 knockout mice are protected from diabetic kidney disease by enhancing mitophagy via FIS1 ...
Mitsuo Kato, Maryam Abdollahi, Ragadeepthi Tunduguru, Walter Tsark, Zhuo Chen, Xiwei Wu, Jinhui Wang, Zhen Bouman Chen, Feng-Mao Lin, Linda Lanting, Mei Wang, Janice Huss, Patrick T Fueger, David Chan, Rama Natarajan   +14 more
doaj   +1 more source

Cardiovascular characterisation of a novel mouse model that combines hypertension and diabetes co-morbidities

Scientific Reports, 2023
Epidemiologic data suggest that the prevalence of hypertension in patients with diabetes mellitus is ∼1.5–2.0 times greater than in matched non-diabetic patients.
Arpeeta Sharma, Judy S. Y. Choi, Anna M. D. Watson, Leila Li, Thomas Sonntag, Man K. S. Lee, Andrew J. Murphy, Miles De Blasio, Geoffrey A. Head, Rebecca H. Ritchie, Judy B. de Haan   +10 more
doaj   +1 more source