Results 31 to 40 of about 1,112,461 (309)

Liraglutide dictates macrophage phenotype in apolipoprotein E null mice during early atherosclerosis

Cardiovascular Diabetology, 2017
Background Macrophages play a pivotal role in atherosclerotic plaque development. Recent evidence has suggested the glucagon-like peptide-1 receptor (GLP-1R) agonist, liraglutide, can attenuate pro-inflammatory responses in macrophages.
Robyn Bruen, Sean Curley, Sarina Kajani, Daniel Crean, Marcella E. O’Reilly, Margaret B. Lucitt, Catherine G. Godson, Fiona C. McGillicuddy, Orina Belton   +8 more
doaj   +1 more source

Effects of the increase in co-payments from 20 to 30 percent on the compliance rate of patients with hypertension or diabetes mellitus in the Employed Health Insurance System [PDF]

, 2005
Objectives: How to contain medical expenditures is a universal problem. The Japanese government has increased patient co-payments to control it. The purpose of this study is to clarify whether the increase in co-payments to 30 percent prevented patients ...
Babazono, Akira, Imatoh, Takuya, Miyazaki, Motonobu, Tanaka, Kiyoshi, Tanihara, Shinichi, Tsuda, Toshihide, Une, Hiroshi, Yamamoto, Eiji   +7 more
core   +1 more source

Relationship between plasma sialic acid and fibinogen concentration and incident micro-and macrovascular complications in type 1 diabetes [PDF]

, 2008
AIMS/HYPOTHESIS: Type 1 diabetes is associated with an increased risk of vascular complications. This increased risk could be explained by sialic acid and/or fibrinogen.
CHATURVEDI N, FULLER JH, MICCOLI, ROBERTO, On behalf of EURODIAB PCS STUDY GROUP, PICKUP JC, SOEDAMAH MUTHU SS   +5 more
core   +7 more sources

Heterogeneity of diabetes outcomes among asians and pacific islanders in the US: the diabetes study of northern california (DISTANCE). [PDF]

, 2011
ObjectiveEthnic minorities with diabetes typically have lower rates of cardiovascular outcomes and higher rates of end-stage renal disease (ESRD) compared with whites.
Adams, Alyce, Adler, Nancy, Ahmed, Ameena T, Kanaya, Alka M, Karter, Andrew J, Liu, Jennifer, Moffet, Howard H, Schillinger, Dean   +7 more
core   +2 more sources

Publisher Correction: miR-379 deletion ameliorates features of diabetic kidney disease by enhancing adaptive mitophagy via FIS1

Communications Biology, 2021
A Correction to this paper has been published: https://doi.org/10.1038/s42003-021-01691 ...
Mitsuo Kato, Maryam Abdollahi, Ragadeepthi Tunduguru, Walter Tsark, Zhuo Chen, Xiwei Wu, Jinhui Wang, Zhen Bouman Chen, Feng-Mao Lin, Linda Lanting, Mei Wang, Janice Huss, Patrick T. Fueger, David Chan, Rama Natarajan   +14 more
doaj   +1 more source

Increased mitochondrial proton leak and glycolysis in peripheral blood mononuclear cells in type-1-diabetes

Heliyon, 2022
Changes in cellular bioenergetics such as mitochondrial respiration and glycolysis may play a role in the pathogenesis of various diseases including type 1 diabetes (T1D).
Joana Mendes Lopes de Melo, Jens Christian Laursen, Niels Søndergaard-Heinrich, Ida Kirstine Bull Rasmussen, Christian Stevns Hansen, Marie Frimodt-Møller, Peter Rossing, Joachim Størling   +7 more
doaj   +1 more source

Reduced Autophagy by a microRNA-mediated Signaling Cascade in Diabetes-induced Renal Glomerular Hypertrophy

Scientific Reports, 2018
Autophagy plays a key role in the pathogenesis of kidney diseases, however its role in diabetic nephropathy (DN), and particularly in kidney glomerular mesangial cells (MCs) is not very clear.
Supriya Deshpande, Maryam Abdollahi, Mei Wang, Linda Lanting, Mitsuo Kato, Rama Natarajan   +5 more
doaj   +1 more source

The AGE receptor, OST48 drives podocyte foot process effacement and basement membrane expansion (alters structural composition)

Endocrinology, Diabetes & Metabolism, 2021
Aims The accumulation of advanced glycation end products is implicated in the development and progression of diabetic kidney disease. No study has examined whether stimulating advanced glycation clearance via receptor manipulation is reno‐protective in ...
Aowen Zhuang, Felicia Y. T. Yap, Danielle J. Borg, Domenica McCarthy, Amelia Fotheringham, Sherman Leung, Sally A. Penfold, Karly C. Sourris, Melinda T. Coughlan, Benjamin L. Schulz, Josephine M. Forbes   +10 more
doaj   +1 more source

Recent advances in the treatment of patients with obesity and chronic kidney disease

Annals of Medicine, 2023
Obesity is a chronic disease characterised by excess adiposity, which impairs health. The high prevalence of obesity raises the risk of long-term medical complications including type 2 diabetes and chronic kidney disease.
Roshaida Abdul Wahab, Ricardo V. Cohen, Carel W. le Roux   +2 more
doaj   +1 more source

Hemorheological Failure in the Pathology of Cardio-vascular Complications in Patients with Diabetic Foot Syndrome [PDF]

, 2016
The literature that includes the study of cardiovascular complications in patients with diabetic foot syndrome was analyzed. The topicality of this problem is caused by the steady growth of diabetes mellitus morbidity among people.
Кorobko, Е. (Еlina)
core   +2 more sources