Results 31 to 40 of about 2,418,589 (310)

Pathophysiology of diabetic complications [PDF]

Diabetologia, 1997
IF 5 ...
POLAK M, NEWFIELD RS, FIORETTO, PAOLA, CZERNICHOW P, MARCHESE R.   +4 more
openaire   +4 more sources

Publisher Correction: miR-379 deletion ameliorates features of diabetic kidney disease by enhancing adaptive mitophagy via FIS1

Communications Biology, 2021
A Correction to this paper has been published: https://doi.org/10.1038/s42003-021-01691 ...
Mitsuo Kato, Maryam Abdollahi, Ragadeepthi Tunduguru, Walter Tsark, Zhuo Chen, Xiwei Wu, Jinhui Wang, Zhen Bouman Chen, Feng-Mao Lin, Linda Lanting, Mei Wang, Janice Huss, Patrick T. Fueger, David Chan, Rama Natarajan   +14 more
doaj   +1 more source

A model to estimate the lifetime health outcomes of patients with Type 2 diabetes: the United Kingdom Prospective Diabetes Study (UKPDS) Outcomes Model (UKPDS no. 68) [PDF]

, 2004
<i>Aims/hypothesis</i> The aim of this study was to develop a simulation model for Type 2 diabetes that can be used to estimate the likely occurrence of major diabetes-related complications over a lifetime, in order to calculate health ...
Stevenson, R.J., Gray, Alastair, Stevens, Richard, Briggs, AH, Holman, RR, Farmer, A.J., Holman, Rury, Fenn, P., Stevens, RJ, Clarke, P.M., Fenn, P,, Fenn, P, Stevens, R.J., Stratton, I.M., Farmer, Andrew, Gray, A, Gray, AM, Farmer, AJ, Stratton, IM, Holman, R, Matthews, D.R., Matthews, DR, Briggs, A., Clarke, PM, Briggs, A, the UK Prospective Diabetes Study (UKPDS) Group, Gray, A.M., Holman, R.R.   +27 more
core   +1 more source

Reduced Autophagy by a microRNA-mediated Signaling Cascade in Diabetes-induced Renal Glomerular Hypertrophy

Scientific Reports, 2018
Autophagy plays a key role in the pathogenesis of kidney diseases, however its role in diabetic nephropathy (DN), and particularly in kidney glomerular mesangial cells (MCs) is not very clear.
Supriya Deshpande, Maryam Abdollahi, Mei Wang, Linda Lanting, Mitsuo Kato, Rama Natarajan   +5 more
doaj   +1 more source

The AGE receptor, OST48 drives podocyte foot process effacement and basement membrane expansion (alters structural composition)

Endocrinology, Diabetes & Metabolism, 2021
Aims The accumulation of advanced glycation end products is implicated in the development and progression of diabetic kidney disease. No study has examined whether stimulating advanced glycation clearance via receptor manipulation is reno‐protective in ...
Aowen Zhuang, Felicia Y. T. Yap, Danielle J. Borg, Domenica McCarthy, Amelia Fotheringham, Sherman Leung, Sally A. Penfold, Karly C. Sourris, Melinda T. Coughlan, Benjamin L. Schulz, Josephine M. Forbes   +10 more
doaj   +1 more source

Increased mitochondrial proton leak and glycolysis in peripheral blood mononuclear cells in type-1-diabetes

Heliyon, 2022
Changes in cellular bioenergetics such as mitochondrial respiration and glycolysis may play a role in the pathogenesis of various diseases including type 1 diabetes (T1D).
Joana Mendes Lopes de Melo, Jens Christian Laursen, Niels Søndergaard-Heinrich, Ida Kirstine Bull Rasmussen, Christian Stevns Hansen, Marie Frimodt-Møller, Peter Rossing, Joachim Størling   +7 more
doaj   +1 more source

Increased glycation and oxidative damage to apolipoprotein B100 of LDL cholesterol in patients with type 2 diabetes and effect of metformin [PDF]

, 2010
OBJECTIVE The aim of this study was to investigate whether apolipoprotein B100 of LDL suffers increased damage by glycation, oxidation, and nitration in patients with type 2 diabetes, including patients receiving metformin therapy.
Rabbani, Naila, D. Zehnder, A. Ceriello, P. J. Thornalley, N. Rabbani, Zehnder, Daniel, Chittari, Madhu Varma, C. W. Bodmer, Bodmer, Charles W., Ceriello, Antonio, M. V. Chittari, Thornalley, Paul J.   +11 more
core   +1 more source

Homozygous receptors for insulin and not IGF-1 accelerate intimal hyperplasia in insulin resistance and diabetes

Nature Communications, 2019
Both insulin and IGF-1 signaling have been implicated in arterial intimal hyperplasia. Here the authors dissect the relative contributions of insulin and IGF-1 receptors, showing that homodimers of insulin receptors, but not IGF-1 receptor, induce ...
Qian Li, Jialin Fu, Yu Xia, Weier Qi, Atsushi Ishikado, Kyoungmin Park, Hisashi Yokomizo, Qian Huang, Weikang Cai, Christian Rask-Madsen, C. Ronald Kahn, George L. King   +11 more
doaj   +1 more source

Recent advances in the treatment of patients with obesity and chronic kidney disease

Annals of Medicine, 2023
Obesity is a chronic disease characterised by excess adiposity, which impairs health. The high prevalence of obesity raises the risk of long-term medical complications including type 2 diabetes and chronic kidney disease.
Roshaida Abdul Wahab, Ricardo V. Cohen, Carel W. le Roux   +2 more
doaj   +1 more source

Association of periodontitis with microvascular complications of diabetes mellitus: A nationwide cohort study

, 2022
Background: Periodontitis is a common chronic inflammatory disease and one of oral complications in diabetes. Diabetes-related microvascular complications and periodontitis are also closely related to systemic inflammation.
김진권
core   +1 more source