Results 11 to 20 of about 1,112,461 (309)

Complications of Diabetes [PDF]

Journal of Diabetes Research, 2015
Diabetes is justly recognized as an emerging global epidemic, representing one of the leading causes of morbidity and mortality worldwide. Hyperglycemia, the common characteristic of both type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM), has the potential to cause serious complications due to its insidious and chronic nature.
Konstantinos Papatheodorou, Maciej Banach, Michael Edmonds, Nikolaos Papanas, Dimitrios Papazoglou   +4 more
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Sestrin2 in diabetes and diabetic complications

Frontiers in Endocrinology, 2023
Diabetes is a global health problem which is accompanied with multi-systemic complications. It is of great significance to elucidate the pathogenesis and to identify novel therapies of diabetes and diabetic complications. Sestrin2, a stress-inducible protein, is primarily involved in cellular responses to various stresses.
Xiaodan Zhang, Zirui Luo, Jiahong Li, Yaxuan Lin, Yu Li, Wangen Li   +5 more
openaire   +3 more sources

Cardiovascular complications of diabetes [PDF]

Diabetologia, 1997
Cardiovascular complications are the leading causesof mortality in both insulin-dependent (IDDM) andnon-insulin-dependent diabetes mellitus (NIDDM).The severity of this problem is clearly illustrated bythe finding that IDDM patients suffer from mortalityrates many times higher than of the general popula-tion [1].
S, Caprio, S, Wong, K G, Alberti, G, King   +3 more
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Pathophysiology of diabetic complications [PDF]

Diabetologia, 1997
IF 5 ...
POLAK M, NEWFIELD RS, FIORETTO, PAOLA, CZERNICHOW P, MARCHESE R.   +4 more
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Gastrointestinal Complications of Diabetes [PDF]

Endocrinology and Metabolism Clinics of North America, 2013
This review provides an overview of the vast gastrointestinal tract complications of diabetes that can occur from the mouth to the anus. The presentation, diagnosis, and management of gastrointestinal disorders, ranging from gastroparesis, celiac disease, and bacterial overgrowth to nonalcoholic fatty liver disease, are reviewed to heighten awareness ...
Brigid S, Boland, Steven V, Edelman, James D, Wolosin   +2 more
openaire   +2 more sources

'Join us on our journey': Exploring the experiences of children and young people with type 1 diabetes and their parents [PDF]

, 2014
This paper focuses on children and young people with type 1 diabetes and on their parents, and their experiences of diabetes care provision. Nine acute hospitals in the Yorkshire and the Humber region, UK, were recruited to participate in a qualitative ...
Department of Health, Department of Health, Diabetes Control and Complications Trial Research Group, Diabetes UK, Diamond Project Group, Epidemiology of Diabetes Interventions and Complications Research Group., Gunn, Kanavos, Kennedy, Kime, Miles, NHS Confederation, Patterson, Peyrot, Randell, The, Wood   +16 more
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Downregulation of hepatic lncRNA Gm19619 improves gluconeogenesis and lipogenesis following vertical sleeve gastrectomy in mice

Communications Biology, 2023
A hepatic lncRNA Gm19619, which is repressed by vertical sleeve gastrectomy but upregulated by obesity and fasting, regulates gluconeogenesis and lipid metabolism in mice through Foxo1-G6pc/Pck1 and Lepr signaling pathway respectively.
Zhipeng Fang, Mingjie Fan, Dongqiang Yuan, Lihua Jin, Yangmeng Wang, Lili Ding, Senlin Xu, Jui Tu, Eryun Zhang, Xiwei Wu, Zhen Bouman Chen, Wendong Huang   +11 more
doaj   +1 more source

Diabetes, hypertension, and cardiovascular disease: clinical insights and vascular mechanisms [PDF]

, 2018
Hypertension and type 2 diabetes are common comorbidities. Hypertension is twice as frequent in patients with diabetes compared with those who do not have diabetes.
Guzik, Tomasz J., Petrie, John R., Touyz, Rhian M.   +2 more
core   +1 more source

Type 1 diabetes and cardiovascular disease [PDF]

, 2013
The presence of cardiovascular disease (CVD) in Type 1 diabetes largely impairs life expectancy. Hyperglycemia leading to an increase in oxidative stress is considered to be the key pathophysiological factor of both micro- and macrovascular complications.
Cappuccio, Francesco, Ceriello, Antonio, Genovese, Stefano, Schnell, Oliver, Standl, E. (Eberhard), Valensi, Paul   +5 more
core   +2 more sources

Evaluation of the zucker diabetic fatty (ZDF) rat as a model for human disease based on urinary peptidomic profiles [PDF]

, 2012
Representative animal models for diabetes-associated vascular complications are extremely relevant in assessing potential therapeutic drugs. While several rodent models for type 2 diabetes (T2D) are available, their relevance in recapitulating renal and ...
Antonia Vlahou, Ariela Benigni, B Jonsson, Bernd Mayer, C Delles, C Weyer, C Zoja, Carlamaria Zoja, CD Wenger, CL Oltman, CS Fox, D Theodorescu, Ferdinand H. Bahlmann, H Mischak, H Mischak, Harald Mischak, J Drube, J Toblli, JO Deguchi, Joachim Jankowski, Julie Klein, Justyna Siwy, K Voros, Karin Jandeleit-Dahm, M Hashemi, M Haubitz, N Ahmed, N Verzijl, ND Rawlings, P Zurbig, Paul Perco, PJ Talmud, PR Cutillas, R Rouse, Robert Stevens, S Andersen, S Wild, SA Varghese, Sophia Kossida, T Nakagawa, TW Kurtz, Wiliam Mullen, Y Benjamini, Y Igarashi   +43 more
core   +3 more sources