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Diabetes and kidney cancer: A direct or indirect association? [PDF]
A positive association between diabetes and kidney cancer has been reported in several investigations, but it is unclear whether diabetes or its complications account for this association.
Bahij S. Nuwayhid +4 more
core +2 more sources
Vascular Complications of Diabetes [PDF]
Over the last several decades, the global incidence and prevalence of diabetes mellitus has increased significantly. The raised incidence rate is projected to continue as greater numbers of persons adopt a Western lifestyle and diet. Patients with diabetes mellitus are at heightened risk of both adverse microvascular and cardiovascular events. Moreover,
Joshua A, Beckman, Mark A, Creager
openaire +2 more sources
Both insulin and IGF-1 signaling have been implicated in arterial intimal hyperplasia. Here the authors dissect the relative contributions of insulin and IGF-1 receptors, showing that homodimers of insulin receptors, but not IGF-1 receptor, induce ...
Qian Li +11 more
doaj +1 more source
A gut feeling for drugs that have metabolic benefits
Resveratrol (REV) is a natural polyphenol with anti-obesity effects. However, the mechanisms remain unclear due to its low bioavailability and the lack of defined membrane-bound or nuclear receptors.
Eryun Zhang, Alon Agua, Wendong Huang
doaj +1 more source
Effect of vitamin D3 supplement in glycemic control of pediatrics with type 1 diabetes mellitus and vitamin D deficiency [PDF]
Background: Glycemic control prevents microvascular complications in patients with type I diabetes mellitus such as retinopathy, nephropathy and neuropathy that influences quality of life.
Fatahi, N. +3 more
core +1 more source
Renal complications of diabetes [PDF]
Diabetic nephropathy is a leading cause of chronic kidney disease (CKD) in the UK. These patients are at significantly increased risk of cardiovascular disease and of progression to end-stage renal disease. We review the epidemiology, pathogenesis and natural history of diabetic nephropathy and evaluate the therapeutic options available.We searched ...
T Z, Min +3 more
openaire +2 more sources
Obesity as a risk factor following cadaveric renal transplantation [PDF]
Obesity has generally been thought to increase the risk of operative mortality and postoperative complications in surgical patients. No data examining obesity as a factor in cadaveric renal transplantation were available.
Hakala, TR +5 more
core +1 more source
A multi-centre qualitative study exploring the experiences of UK South Asian and White Diabetic Patients referred for renal care [PDF]
Background An exploration of renal complications of diabetes from the patient perspective is important for developing quality care through the diabetic renal disease care pathway.
AC Burden +24 more
core +4 more sources
Nephropathy is a common and hard-to-treat consequence of diabetes. Here Kato et al. show that a megacluster of microRNAs regulates early development of diabetic nephropathy in mice, and that inhibition of the cluster's host long non-coding RNA transcript
Mitsuo Kato +14 more
doaj +1 more source

