Results 41 to 50 of about 1,112,461 (309)

Diabetes and kidney cancer: A direct or indirect association? [PDF]

open access: yes, 2010
A positive association between diabetes and kidney cancer has been reported in several investigations, but it is unclear whether diabetes or its complications account for this association.
Bahij S. Nuwayhid   +4 more
core   +2 more sources

Vascular Complications of Diabetes [PDF]

open access: yesCirculation Research, 2016
Over the last several decades, the global incidence and prevalence of diabetes mellitus has increased significantly. The raised incidence rate is projected to continue as greater numbers of persons adopt a Western lifestyle and diet. Patients with diabetes mellitus are at heightened risk of both adverse microvascular and cardiovascular events. Moreover,
Joshua A, Beckman, Mark A, Creager
openaire   +2 more sources

Homozygous receptors for insulin and not IGF-1 accelerate intimal hyperplasia in insulin resistance and diabetes

open access: yesNature Communications, 2019
Both insulin and IGF-1 signaling have been implicated in arterial intimal hyperplasia. Here the authors dissect the relative contributions of insulin and IGF-1 receptors, showing that homodimers of insulin receptors, but not IGF-1 receptor, induce ...
Qian Li   +11 more
doaj   +1 more source

A gut feeling for drugs that have metabolic benefits

open access: yesNature Communications, 2023
Resveratrol (REV) is a natural polyphenol with anti-obesity effects. However, the mechanisms remain unclear due to its low bioavailability and the lack of defined membrane-bound or nuclear receptors.
Eryun Zhang, Alon Agua, Wendong Huang
doaj   +1 more source

Effect of vitamin D3 supplement in glycemic control of pediatrics with type 1 diabetes mellitus and vitamin D deficiency [PDF]

open access: yes, 2015
Background: Glycemic control prevents microvascular complications in patients with type I diabetes mellitus such as retinopathy, nephropathy and neuropathy that influences quality of life.
Fatahi, N.   +3 more
core   +1 more source

Renal complications of diabetes [PDF]

open access: yesBritish Medical Bulletin, 2012
Diabetic nephropathy is a leading cause of chronic kidney disease (CKD) in the UK. These patients are at significantly increased risk of cardiovascular disease and of progression to end-stage renal disease. We review the epidemiology, pathogenesis and natural history of diabetic nephropathy and evaluate the therapeutic options available.We searched ...
T Z, Min   +3 more
openaire   +2 more sources

Obesity as a risk factor following cadaveric renal transplantation [PDF]

open access: yes, 1990
Obesity has generally been thought to increase the risk of operative mortality and postoperative complications in surgical patients. No data examining obesity as a factor in cadaveric renal transplantation were available.
Hakala, TR   +5 more
core   +1 more source

A multi-centre qualitative study exploring the experiences of UK South Asian and White Diabetic Patients referred for renal care [PDF]

open access: yes, 2012
Background An exploration of renal complications of diabetes from the patient perspective is important for developing quality care through the diabetic renal disease care pathway.
AC Burden   +24 more
core   +4 more sources

An endoplasmic reticulum stress-regulated lncRNA hosting a microRNA megacluster induces early features of diabetic nephropathy

open access: yesNature Communications, 2016
Nephropathy is a common and hard-to-treat consequence of diabetes. Here Kato et al. show that a megacluster of microRNAs regulates early development of diabetic nephropathy in mice, and that inhibition of the cluster's host long non-coding RNA transcript
Mitsuo Kato   +14 more
doaj   +1 more source

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