Results 41 to 50 of about 1,073,655 (357)
Recent advances in the treatment of patients with obesity and chronic kidney disease
Annals of Medicine, 2023 Obesity is a chronic disease characterised by excess adiposity, which impairs health. The high prevalence of obesity raises the risk of long-term medical complications including type 2 diabetes and chronic kidney disease.
Roshaida Abdul Wahab +2 more
doaj +1 more source
Scientific Reports, 2018 Autophagy plays a key role in the pathogenesis of kidney diseases, however its role in diabetic nephropathy (DN), and particularly in kidney glomerular mesangial cells (MCs) is not very clear.
Supriya Deshpande +5 more
doaj +1 more source
A gut feeling for drugs that have metabolic benefits
Nature Communications, 2023 Resveratrol (REV) is a natural polyphenol with anti-obesity effects. However, the mechanisms remain unclear due to its low bioavailability and the lack of defined membrane-bound or nuclear receptors.
Eryun Zhang, Alon Agua, Wendong Huang
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Obesity as a risk factor following cadaveric renal transplantation [PDF]
, 1990 Obesity has generally been thought to increase the risk of operative mortality and postoperative complications in surgical patients. No data examining obesity as a factor in cadaveric renal transplantation were available.
Hakala, TR +5 more
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Hemorheological Failure in the Pathology of Cardio-vascular Complications in Patients with Diabetic Foot Syndrome [PDF]
, 2016 The literature that includes the study of cardiovascular complications in patients with diabetic foot syndrome was analyzed. The topicality of this problem is caused by the steady growth of diabetes mellitus morbidity among people.
Кorobko, Е. (Еlina)
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Renal complications of diabetes [PDF]
British Medical Bulletin, 2012 Diabetic nephropathy is a leading cause of chronic kidney disease (CKD) in the UK. These patients are at significantly increased risk of cardiovascular disease and of progression to end-stage renal disease. We review the epidemiology, pathogenesis and natural history of diabetic nephropathy and evaluate the therapeutic options available.We searched ...
T Z, Min +3 more
openaire +2 more sources
Nature Communications, 2019 Both insulin and IGF-1 signaling have been implicated in arterial intimal hyperplasia. Here the authors dissect the relative contributions of insulin and IGF-1 receptors, showing that homodimers of insulin receptors, but not IGF-1 receptor, induce ...
Qian Li +11 more
doaj +1 more source
Regional trends in avoidable hospitalisations due to complications among population with diabetes in Finland in 1996-2011 : a register-based cohort study [PDF]
, 2016 Objectives: Diabetes requires continuous medical care including prevention of acute complications and risk reduction for long-term complications. Diabetic complications impose a substantial burden on public health and care delivery. We examined trends in
Arffman, Martti +5 more
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, 2018 Type 1 diabetes is a chronic autoimmune disease characterised by insulin deficiency and resultant hyperglycaemia. Knowledge of type 1 diabetes has rapidly increased over the past 25 years, resulting in a broad understanding about many aspects of the ...
DiMeglio, Linda A. +2 more
core +1 more source
Murine Nephrotoxic Nephritis as a Model of Chronic Kidney Disease
International Journal of Nephrology, 2018 Using the nonaccelerated murine nephrotoxic nephritis (NTN) as a model of chronic kidney disease (CKD) could provide an easily inducible model that enables a rapid test of treatments.
M. K. E. Ougaard +5 more
doaj +1 more source