Results 121 to 130 of about 1,490,009 (294)

Activating the Osteoblastic USP26 Pathway Alleviates Multi‐Organ Fibrosis by Decreasing Insulin Resistance

Advanced Science, EarlyView.
The loss of Ubiquitin Specific Peptidase 26 (USP26) in osteoblasts results in decreased bone formation, as well as multi‐organ fibrosis associated with insulin resistance (IR). Mechanistically, the absence of USP26 reduces glycolysis and lactate accumulation, leading to decreased histone H3 lysine 18 lactylation (H3K18LA) in the promoter region of KH ...
Jiyuan Tang, Wenkai Ye, Liang He, Zhou Dan, Leilei Chang, Zijie You, Yuanyue Jiang, Guoqing Tang, Lianfu Deng, Changwei Li   +9 more
wiley   +1 more source

Association of RPS26 gene polymorphism with different types of diabetes in Chinese individuals

Journal of Diabetes Investigation
Aims/Introduction Different types of diabetes show distinct genetic characteristics, but the specific genetic susceptibility factors remain unclear. Our study aimed to explore the associations between the ribosomal protein S26 (RPS26) gene rs1131017 ...
Rong Song, Lingxiang Xie, Jin Ding, Yan Chen, Hailan Zou, Haipeng Pang, Yiman Peng, Ying Xia, Zhiguo Xie, Xia Li, Yang Xiao, Zhiguang Zhou, Jingyi Hu   +12 more
doaj   +1 more source

Environmental Factors Associated With Type 1 Diabetes Mellitus

Diyala Journal of Medicine, 2021
Background: Type 1diabetes (T1D) is immune-mediated disease that presented as a consequence of the gradual destruction of the insulin- producing beta cells, which in results total beta-cell loss and complete dependence on exogenous insulin. Objective:
Safa Raad Ghareeb , Jalil Ibrahim Alezzi, Aseel Jasim Mohammed   +2 more
doaj  

Diabetes mellitus type 1: is it a global challenge? [PDF]

, 2016
Type 1 diabetes, a serious and life-threatening disease with many complications, is one of the most common (autoimmune) endocrine and metabolic conditions in childhood, with life-saving treatment and lifelong, but painful and time-consuming in daily ...
Amiri, Masoud., Hosseini, Seyed masih., Maghsoudi, Reza.   +2 more
core  

A Time‐Programmed Bilayer Wound Dressing for Dynamic Microenvironment Modulation and Full‐Thickness Regeneration in Diabetic Wounds

Advanced Science, EarlyView.
The Polyphenol+PDGF‐BB scaffold fabrication (Panel A) and its dual wound healing effects (Panel B: anti‐inflammation and accelerated tissue remodeling). ABSTRACT Chronic diabetic wounds suffer from dysfunctional repair programs due to accumulated advanced glycation end products (AGEs) and persistent inflammation in hyperglycemic microenvironments ...
Lei Yi, Wanqian Li, Ying Duanmu, Zihan Zhang, Shixuan Chen, Shichu Xiao, Lei Du, Miaomiao Wei   +7 more
wiley   +1 more source

Hepatic insulin synthesis increases in rat models of diabetes mellitus type 1 and 2 differently. [PDF]

PLoS One, 2023
Abidov M, Sokolova K, Danilova I, Baykenova M, Gette I, Mychlynina E, Aydin Ozgur B, Gurol AO, Yilmaz MT.   +8 more
europepmc   +1 more source

Self-care in children with newfound type 1 diabetes mellitus [PDF]

Innledning Type 1 diabetes mellitus er hyppigst utbredt blant barn (Sagen 2011), og i Norge er det over 300 barn som får diagnosen hvert år (Barn og diabetes 2015).
Lien, Kine Holm, Myhre, Martine, Thomlevold, Cathrine   +2 more
core  

Microglial Fkbp5 Impairs Post‐Stroke Vascular Integrity and Regeneration by Promoting Yap1‐Mediated Glycolysis and Oxidative Phosphorylation

Advanced Science, EarlyView.
A post‐stroke perivascular niche of microglia characterized by low expression of M2 markers and elevated glycolysis, oxidative phosphorylation (OXPHOS), and phagocytic activity is identified, which is termed stroke‐activated vascular‐associated microglia (stroke‐VAM).
Yanan Li, Yanmei Qiu, Yunlei Yang, Yanhao Wei, Haokun Peng, Longhai Zeng, Pengcheng Li, Rentang Bi, Bo Hu   +8 more
wiley   +1 more source

Fulminant type 1 diabetes: A distinct subtype of type 1 diabetes mellitus

Journal of the Formosan Medical Association, 2013
Jiao Fu, Bing-Yin Shi
doaj   +1 more source

Bioleptin as a useful marker of metabolic status in children with diabetes mellitus type 1. [PDF]

Front Endocrinol (Lausanne), 2023
Jakubek-Kipa K, Galiniak S, Łagowska K, Krupa I, Ludwin A, Tabarkiewicz J, Mazur A.   +6 more
europepmc   +1 more source