Results 131 to 140 of about 1,446,872 (351)

Type 2 Diabetes‐Associated Phenylacetylglutamine Induces Deleterious Inflammation Cycle in Myeloid Cells through β2 Adrenergic Receptors and Impedes Wound Healing

Advanced Science, EarlyView.
The microbiota‐derived metabolite phenylacetylglutamine (PAGln) is elevated in type 2 diabetes and tightly associated with poor healing in both diabetic and non‐diabetic human patients. PAGln promotes mouse inflammation and impairs healing through a transmissible β2‐adrenergic receptor–mediated trained‐immunity loop.
Lu Huang, Xinran Ye, Chia‐Kang Ho, Ya Gao, Dongsheng Wen, Jiaming Sun, Yuxin Liu, Yangdan Liu, Guoyuan Wang, Yangbai Sun, Jinyan Zhang, Yifan Zhang, Qingfeng Li   +12 more
wiley   +1 more source

PHARMACOLOGICAL NEUROPROTECTION OF TYPE 1 DIABETES MELLITUS

Ukrainian Scientific Medical Youth Journal, 2016
Type 1 diabetes mellitus (DM) - one of the most common diseases of modern endocrinology. The growing number of sick children, emergence of chronic diseases and high percentage of disability determine the severity of the problem. Diabetic neuropathy (DN),
O. Fitsner, M. Khaitovych
doaj  

Erythrocyte membrane acetylcholinesterase in type 1 (insulin-dependent) diabetes mellitus [PDF]

, 1989
Mohammad Suhail, Syed Ibrahim Rizvi
openalex   +1 more source

Transfer Learning and Permutation‐Invariance Improving Predicting Genome‐Wide, Cell‐Specific and Directional Interventions Effects of Complex Systems

Advanced Science, EarlyView.
SETComp, a transfer learning model based on permutation‐invariance, is pre‐trained on single‐compound intervention data and fine‐tuned on complex system (e.g., natural products) data. The model achieves up to 93.86% accuracy on complex system‐cell‐gene association predictions, outperforming the baseline by up to 27.59%.
Boyang Wang, Boyu Pan, Tingyu Zhang, Qingyuan Liu, Shao Li   +4 more
wiley   +1 more source

Neglected-Noncompliant Type 1 Diabetes Mellitus with Complications

Jurnal Kesehatan Andalas, 2012
AbstrakDiabetes mellitus (DM) tipe 1 merupakan kelainan sistemik akibat terjadinya gangguan metabolisme glukosayang ditandai oleh hiperglikemia kronis.
Afdal ., Eka Agustia Rini
doaj  

Environmental Factors Associated With Type 1 Diabetes Mellitus

Diyala Journal of Medicine, 2021
Background: Type 1diabetes (T1D) is immune-mediated disease that presented as a consequence of the gradual destruction of the insulin- producing beta cells, which in results total beta-cell loss and complete dependence on exogenous insulin. Objective:
Safa Raad Ghareeb , Jalil Ibrahim Alezzi, Aseel Jasim Mohammed   +2 more
doaj  

Islet cell surface antibodies in Type 1 (insulin-dependent) diabetes mellitus: Use of human fetal pancreas cultures as substrate [PDF]

, 1982
Ricardo Pujol‐Borrell, E L Khoury, G. F. Bottazzo   +2 more
openalex   +1 more source

Bacteria‐Targeted Single‐Atom Nanozyme With Photothermal‐Augmented Multi‐Enzymatic Cascade and NO Delivery for Enhanced Infected Wound Healing

Advanced Science, EarlyView.
A single‐atom nanozyme‐based multifunctional nanoplatform synergizes bacterial targeting with a NIR‐II responsive therapeutic cascade for effective diabetic wound management. This nanoplatform enhances biofilm destruction through photothermal‐augmented biocatalysis while simultaneously activating endothelial cells by delivering nitric oxide to promote ...
Junyang Chen, Qing Chen, Xudong Qin, Haixia Yang, Xin Wang, Jianliang Zhou, Ying‐Wei Yang, Jian Tian   +7 more
wiley   +1 more source

Problems of applying inflammatory markers to diagnostics of anemia of chronic disease in patients with type 1 and type 2 diabetes

Медицинская иммунология
The purpose of the study was to evaluate the severity of changes in the values of markers-candidates for the differential diagnosis of anemia of chronic diseases in patients with type 1 and type 2 diabetes mellitus.
N. N. Musina, T. S. Prokhorenko, T. V. Saprina, A. P. Zima   +3 more
doaj   +1 more source

Islet cell and insulin autoantibodies in subjects at high risk for development of Type 1 (insulin-dependent) diabetes mellitus: the Lyon family study [PDF]

, 1988
C. Thivolet, B. Beaufr�re, H. B�tuel, L. Gebuhrer, Pierre Chatelain, A. Durand, J Tourniaire, R. Fran�ois   +7 more
openalex   +1 more source