For those intolerant to ACE inhibitors and ARBs, what is the best therapy for reducing the risk of diabetic nephropathy? [PDF]
Angiotensin-converting enzyme (ACE) inhibitors and angiotensin-receptor blockers (ARBs) are the first-line agents for reducing the risk of diabetic nephropathy.
Penmetsa, Santhi, Simmons, Michael
core
Oral contraceptive progestins and angiotensin-dependent control of the renal circulation in humans [PDF]
Oral contraceptive (OC) use is associated with increased intra-renal renin-angiotensin-aldosterone system (RAA System) activity and risk of nephropathy, though the contribution of progestins contained in the OC in the regulation of angiotensin-dependent ...
Ahmed, Sofia B. +3 more
core +1 more source
Abstract Levothyroxine (LT4) is the standard treatment for hypothyroidism and the most widely prescribed medication worldwide. Although generally safe, regulatory reports list potential cardiac, neuropsychiatric and musculoskeletal adverse events (AEs). Clarifying their clinical relevance is essential.
Bala Swetha Baskaran +2 more
wiley +1 more source
Type 1 diabetes mellitus is the most common metabolic disease in childhood, which may, after years, lead to late vascular complications, including diabetic kidney disease.
Konstancja Fornalczyk +6 more
doaj +1 more source
Novel role of parathyroid hormone-related protein in the pathophysiology of the diabetic kidney: Evidence from experimental and human diabetic nephropathy [PDF]
Parathyroid hormone-related protein (PTHrP) and its receptor type 1 (PTH1R) are extensively expressed in the kidney, where they are able to modulate renal function. Renal PTHrP is known to be overexpressed in acute renal injury. Recently, we hypothesized
Arenas, María Isabel +7 more
core +4 more sources
ABSTRACT Background Optical coherence tomography (OCT)‐guided percutaneous coronary intervention (PCI) enhances treatment of complex coronary artery lesions, including left main (LM) disease, by enabling lesion morphology assessment and stent optimization, thereby reducing major adverse cardiac events (MACE).
Prathap Kumar +4 more
wiley +1 more source
Characterization of diabetic patients with Microalbuminuria
Background: diabetic nephropathy is the cause of 10 to 15 % of chronically ill terminal patients and a significant percentage are diagnosed in very advanced stages.Objective: to characterize, from the clinical and epidemiological point of view, the ...
Pilar Laborí Quesada +4 more
doaj
Use of Antihypertensive Agents and Association With Risk of Adverse Outcomes in Chronic Kidney Disease: Focus on Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers. [PDF]
Background Our objective was to determine patterns of antihypertensive agent use by stage of chronic kidney disease (CKD) and to evaluate the association between different classes of antihypertensive agents with nonrenal outcomes, especially in advanced ...
Johansen, Kirsten L +4 more
core
Histopathological findings in elderly patients [PDF]
INTRODUCTION: The elderly population has significantly increased worldwide and recent studies have evidenced a 10-year increase in Brazilian life expectancy.
Bastos, Marcus Gomes +4 more
core +2 more sources
Exploring the Anti‐Diabetic Potential of Anthocyanins: From Biochemical Pathways to Human Trials
ABSTRACT Diabetes mellitus (DM) is a global health challenge with increasing prevalence rates, particularly in low‐ and middle‐income countries. Anthocyanins (ACs) are potential bioactive compounds found in various fruits and vegetables, attracting the attention of researchers due to their possible role in managing diabetes and its complications ...
Lakshay Panchal +6 more
wiley +1 more source

