Results 171 to 180 of about 37,693 (353)

Targeting ROCK1/YAP1 Axis Ameliorates Inflammation‐Induced Prostatic Hyperplasia via Stabilising SIRT1‐Dependent Mitochondrial Dynamics

Cell Proliferation, EarlyView.
Prostate‐specific YAP1 overexpression induces pathological BPH phenogenesis. Targeting ROCK1/YAP1 with fasudil and verteporfin alleviates inflammatory BPH lesions. YAP1 orchestrates mitochondrial dysfunction and oxidative stress via suppressing SIRT1 function.
Dongxu Lin, Pengyu Wei, Mengyang Zhang, Kang Li, Lina Li, Zhipeng Li, Changcheng Luo, Wenbo Kuang, Kai Cui, Zhong Chen   +9 more
wiley   +1 more source

Mitoxyperilysis: A Novel Cell Death Pathway With Transformative Implications for Organ Pathophysiology and Therapeutic Innovation

Organ Medicine, EarlyView.
Wenhao Shen, Junmei Li, Weifeng Hu
wiley   +1 more source

Progression of albumin/creatinine ratio (ACR) and estimated glomerular filtration rate (eGFR) over 24 years in people with type 2 diabetes. Drivers, potential protectors and associated mortality

Diabetic Medicine, EarlyView.
Abstract Introduction The pathophysiology of chronic kidney disease (CKD) and type 2 diabetes (T2D) is multifactorial and associated with a plethora of underlying conditions and complications. Their link is reciprocal and understanding its nature, particularly over time, could improve the health of many.
Andreas Matheou, Orestis Zavlis, Steve White, Thomas McDonnell, Alexander Warner‐Levy, John Warner‐Levy, Loren Wilkins, Hellena Habte‐Asres, Abigail Lay, Liliana Shalamanova, Martin Whyte, Martin Gibson, Philip A. Kalra, Adrian Heald   +13 more
wiley   +1 more source

Prognostic models for all‐cause and cardiovascular mortality in type 2 diabetes: Systematic review

Diabetic Medicine, EarlyView.
Abstract Aims The elevated risk of all‐cause and cardiovascular mortality in individuals with type 2 diabetes mellitus (T2DM) has led to growing efforts to develop prognostic models for early identification of high‐risk individuals. This systematic review synthesised existing models to inform future model development, enhance predictive performance and
Monica Kundu, Mark P. Funnell, Zahra Karimi, Setor K. Kunutsor, Sara Naderpour, Arron Peace, Anneka Welford, Francesco Zaccardi, Kamlesh Khunti, Safoora Gharibzadeh, Ash Routen   +10 more
wiley   +1 more source

Adult congenital megacolon with acute fecal obstruction and diabetic nephropathy: A case report

, 2019
Mingyuan Zhang, Kefeng Ding
openalex   +2 more sources

A UK key opinion leader perspective: Navigating the immunological and logistical transformation brought by stem cell‐derived islets for the treatment of type 1 diabetes

Diabetic Medicine, EarlyView.
Abstract Aims To explore UK key‐opinion leader perspectives on the future role of stem cell‐derived islets (sc‐islets) in islet transplantation for people with type 1 diabetes (T1D). Methods Four UK‐based key‐opinion leaders evaluated current limitations of donor islet transplantation and reviewed emerging evidence, clinical pathways and logistical ...
Thomas Strakosch, Shareen Forbes
wiley   +1 more source

The Ameliorative Effect of Zingiber officinale in Diabetic Nephropathy [PDF]

, 2014
Nasri, H., Rafieian-Kopaei, M.
core   +1 more source

Neutrophil Elastase, Neuron-Specific Enolase, and S100B Protein as Potential Markers of Long-Term Complications Caused by COVID-19 in Patients with Type 2 Diabetes Mellitus (T2DM) and Advanced Stage of Diabetic Nephropathy (NfT2DM)—Observational Studies [PDF]

Maciej Rabczyński, Sandra Chwałek, Joanna Adamiec-Mroczek, Łukasz Lewandowski, Małgorzata Trocha, Beata Nowak, Marta Misiuk‐Hojło, Dorota Bednarska-Chabowska, Edwin Kuźnik, Paweł Lubieniecki, Joanna Kluz, Zofia Kaszubowska, M. Kondracki, Walter J. Grodzki, Jakub Federowicz, Magdalena Mierzchała-Pasierb, Andrzej Gamian, Agnieszka Bronowicka-Szydełko, Katarzyna Madziarska   +18 more
openalex   +1 more source

Endothelial Nitric Oxide Synthase 4a/B Polymorphism and Its Interaction with Enos G894T Variants in Type 2 Diabetic Pa-tients: Modifying the Risk of Diabetic Nephropathy

, 2022
Mahsa Mohammadi, Hamid Yaghooti, Azim Adibmanesh, Narges Mohammadtaghvaie, Ali Karimi Akhormeh, Maryam Eslami   +5 more
openalex   +1 more source

Carnosinase-1 overexpression, but not aerobic exercise training, affects the development of diabetic nephropathy in BTBR ob/ob mice [PDF]

, 2020
Inge Everaert, Junling He, Maxime Hanssens, Jan Stautemas, Kim H. Bakker, Thomas Albrecht, Shiqi Zhang, Thibaux Van der Stede, Kenneth Vanhove, Muhammad F.A. Chaudhary, Michael Howsam, Frédéric J. Tessier, Benito Yard, Shahid P. Baba, Hans J. Baelde, Wim Derave   +15 more
openalex   +1 more source