Results 31 to 40 of about 37,693 (353)
Managing diabetic nephropathy [PDF]
Clinical Medicine, 2010 The earliest sign of DN is the development of microalbuminuria which is associated with a significant risk of both progressive renal failure and premature death from cardiovascular disease. Optimal glycaemic and BP control, including the use of RAAS blocking drugs, can prevent, slow and even reverse the processes causing DN.
Shields, Joanne, Maxwell, Alexander P
openaire +2 more sources
The Association Between Smoking Tobacco After a Diagnosis of Diabetes and the Prevalence of Diabetic Nephropathy in the Korean Male Population [PDF]
Journal of Preventive Medicine and Public Health, 2016 Objectives: Smoking is known to be associated with nephropathy in patients with diabetes. The distinct effects of smoking before and after diabetes has been diagnosed, however, are not well characterized. We evaluated the association of cigarette smoking
Hyungseon Yeom +3 more
doaj +1 more source
Novel biomarkers for diabetic kidney disease [PDF]
Kidney Research and Clinical Practice, 2022 Although diabetic kidney disease (DKD) remains one of the leading causes of reduced lifespan in patients with diabetes mellitus; its prevalence has failed to decline over the past 30 years.
Chan-Young Jung, Tae-Hyun Yoo
doaj +1 more source
Apolipoprotein L1 gene variants associate with prevalent kidney but not prevalent cardiovascular disease in the Systolic Blood Pressure Intervention Trial. [PDF]
, 2015 Apolipoprotein L1 gene (APOL1) G1 and G2 coding variants are strongly associated with chronic kidney disease (CKD) in African Americans (AAs). Here APOL1 association was tested with baseline estimated glomerular filtration rate (eGFR), urine albumin ...
Bild, Diane E +14 more
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Proteinuria in Primary and Secondary Renal Diseases [PDF]
Journal of Clinical and Diagnostic Research, 2012 Proteinuria is a strong indicator of kidney disease. Various pathological conditions such as diabetes mellitus, cardiovascular disease and hypertension have been shown to provoke secondary kidney problems and significant proteinuria.
Anuradha B. Patil +2 more
doaj
Stage-specific action of matrix metalloproteinases influences progressive hereditary kidney disease. [PDF]
, 2006 BackgroundGlomerular basement membrane (GBM), a key component of the blood-filtration apparatus in the in the kidney, is formed through assembly of type IV collagen with laminins, nidogen, and sulfated proteoglycans.
Cosgrove, Dominic +8 more
core +3 more sources
HIV-related nephropathy: A South African perspective [PDF]
, 2005 Human immunodeficiency virus (HIV)-associated nephropathy (HIVAN) is an important cause of renal failure in those of African origin. A number of other kidney diseases occur in HIV-positive patients.
Gerntholtz, T.E. +2 more
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Silent diabetic nephropathy [PDF]
Kidney International, 2016 Moderately increased albuminuria is widely accepted as the first clinical sign of diabetic nephropathy. However, previous morphometric studies and the autopsy study by Klessens et al. have clearly demonstrated that by the time moderately increased albuminuria is evident, the kidneys in some diabetic patients have already undergone glomerular and ...
Samar M, Said, Samih H, Nasr
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Pharmaceutical BiologyContext Diabetic nephropathy (DN) is a major complication of diabetes mellitus and is the leading cause of kidney disease in patients undergoing renal replacement therapy.
Dengpiao Xie +3 more
doaj +1 more source
Involvement of heparanase in the pathogenesis of acute kidney injury: Nephroprotective effect of PG545 [PDF]
, 2017 Despite the high prevalence of acute kidney injury (AKI) and its association with increased morbidity and mortality, therapeutic approaches for AKI are disappointing. This is largely attributed to poor understanding of the pathogenesis of AKI. Heparanase,
Abassi, Zaid +16 more
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