Results 11 to 20 of about 753,615 (353)

Mechanistic Pathogenesis of Endothelial Dysfunction in Diabetic Nephropathy and Retinopathy

open access: yesFrontiers in Endocrinology, 2022
Diabetic nephropathy (DN) and diabetic retinopathy (DR) are microvascular complications of diabetes. Microvascular endothelial cells are thought to be the major targets of hyperglycemic injury.
Jing Yang, Zhangsuo Liu
semanticscholar   +1 more source

Programmed Cell Death in Diabetic Nephropathy: A Review of Apoptosis, Autophagy, and Necroptosis

open access: yesMedical Science Monitor, 2022
Diabetic nephropathy is a common complication of type I and type II diabetes, in which renal glomeruli are destroyed, resulting in renal damage, proteinuria, and hypertension.
N. Erekat
semanticscholar   +1 more source

Diabetic nephropathy [PDF]

open access: yesDiabetology & Metabolic Syndrome, 2009
Diabetic nephropathy is the leading cause of chronic renal disease and a major cause of cardiovascular mortality. Diabetic nephropathy has been categorized into stages: microalbuminuria and macroalbuminuria. The cut-off values of micro- and macroalbuminuria are arbitrary and their values have been questioned.
Jorge Dias de Matos   +5 more
openaire   +4 more sources

MicroRNA 146a is associated with diabetic complications in type 1 diabetic patients from the EURODIAB PCS

open access: yesJournal of Translational Medicine, 2021
Background MicroRNA-146a-5p (miR-146a-5p) is a key regulator of inflammatory processes. Expression of miR-146a-5p is altered in target organs of diabetic complications and deficiency of miR-146a-5p has been implicated in their pathogenesis.
Federica Barutta   +11 more
doaj   +1 more source

Early detection of diabetic nephropathy in patient with type 2 diabetes mellitus: A review of the literature

open access: yesDiabetes & vascular disease research, 2021
Type 2 diabetes mellitus is a pathology of heterogeneous etiology characterized by hyperglycemia resulting from lack of insulin action, insulin secretion, or both, and the population with diabetes mellitus is predicted to be about 439 million worldwide ...
Sopida Thipsawat
semanticscholar   +1 more source

Risk Factors of Diabetic Nephropathy Among A Group of Iraqi Children with Type 1 Diabetes Mellitus

open access: yesThe Iraqi Journal of Medical Sciences, 2023
Background: Diabetic nephropathy is the major cause of end-stage kidney disease in patients with diabetes mellitus. Objective: To identify risk factors for occurrence of Diabetic nephropathy among group of Iraqi children with type 1 diabetes ...
Mohammed Hammoud   +3 more
doaj   +1 more source

Excessive Activation of Notch Signaling in Macrophages Promote Kidney Inflammation, Fibrosis, and Necroptosis

open access: yesFrontiers in Immunology, 2022
Diabetic nephropathy (DN) is one of the main causes of end-stage renal disease (ESRD). Existing treatments cannot control the progression of diabetic nephropathy very well. In diabetic nephropathy, Many monocytes and macrophages infiltrate kidney tissue.
Tiankui Ma   +13 more
doaj   +1 more source

Diabetic Nephropathy [PDF]

open access: yesDiabetes Care, 2005
Perspectives on the News commentaries are part of a free monthly CME activity. The Mount Sinai School of Medicine, New York, New York, designates this activity for 2.0 AMA PRA Category 1 credits. If you wish to participate, review this article and visit www.diabetes.procampus.net to complete a posttest and receive a certificate.
openaire   +9 more sources

An updated overview of diabetic nephropathy: Diagnosis, prognosis, treatment goals and latest guidelines

open access: yesDiabetes, obesity and metabolism, 2020
Diabetic nephropathy (DN) is a major healthcare challenge. It occurs in up to 50% of those living with diabetes, is a major cause of end‐stage kidney disease (ESKD) that requires treatment with dialysis or renal transplantation, and is associated with ...
N. Selby, M. Taal
semanticscholar   +1 more source

Flavonoids on diabetic nephropathy: advances and therapeutic opportunities

open access: yesChinese Medicine, 2021
With the advances in biomedical technologies, natural products have attracted substantial public attention in the area of drug discovery. Flavonoids are a class of active natural products with a wide range of pharmacological effects that are used for the
Qichao Hu   +9 more
semanticscholar   +1 more source

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