Results 21 to 30 of about 753,615 (353)

The association and prediction value of acylcarnitine on diabetic nephropathy in Chinese patients with type 2 diabetes mellitus

Diabetology & Metabolic Syndrome, 2023
Background Acylcarnitines play a role in type 2 diabetes mellitus (T2DM), but the relationship between acylcarnitine and diabetic nephropathy was unclear.
Xuerui Li, Yuyang Miao, Zhongze Fang, Qiang Zhang   +3 more
doaj   +1 more source

Antiinflammatory Actions of Klotho: Implications for Therapy of Diabetic Nephropathy

International Journal of Molecular Sciences, 2021
Klotho was initially introduced as an antiaging molecule. Klotho deficiency significantly reduces lifespan, and its overexpression extends it and protects against various pathological phenotypes, especially renal disease.
M. Typiak, A. Piwkowska
semanticscholar   +1 more source

The relationship between melatonin level and antioxidant enzymes in diabetic patients with and without nephropathy

Baghdad Journal of Biochemistry and Applied Biological Sciences, 2023
Background and objective: Diabetes is the most common cause of chronic renal disease globally. Diabetic nephropathy (DN) is one of the most serious consequences of type 2 diabetes.
Asaad Al-Khafaji, Seyed M. Mir, Fatemeh Mohammadzadeh, Maryam Abolghasemi, Mahmoud H. Hadwan   +4 more
doaj   +1 more source

Dietary Fiber Protects against Diabetic Nephropathy through Short-Chain Fatty Acid-Mediated Activation of G Protein-Coupled Receptors GPR43 and GPR109A.

Journal of the American Society of Nephrology, 2020
BACKGROUND Studies have reported "dysbiotic" changes to gut microbiota, such as depletion of gut bacteria that produce short-chain fatty acids (SCFAs) through gut fermentation of fiber, in CKD and diabetes.
Y. Li, Xiaochen Chen, Tony K Kwan, Y. Loh, J. Singer, Yunzi Liu, Jin Ma, Jian Tan, L. Macia, C. Mackay, S. Chadban, Hui-ling Wu   +11 more
semanticscholar   +1 more source

Inflammatory Targets in Diabetic Nephropathy

Journal of Clinical Medicine, 2020
One of the most frequent complications in patients with diabetes mellitus is diabetic nephropathy (DN). At present, it constitutes the first cause of end stage renal disease, and the main cause of cardiovascular morbidity and mortality in these patients.
J. Donate-Correa, D. Luis-Rodríguez, E. Martín-Núñez, VICTOR GARCIA TAGUA, C. Hernández-Carballo, C. Ferri, A. E. Rodríguez-Rodríguez, C. Mora-Fernández, J. Navarro-González   +8 more
semanticscholar   +1 more source

MicroRNAs in Podocyte Injury in Diabetic Nephropathy

Frontiers in Genetics, 2020
Diabetic nephropathy is one of the major complications of diabetes mellitus and is the leading cause of end-stage renal disease worldwide. Podocyte injury contributes to the development of diabetic nephropathy.
Hiroki Ishii, Shohei Kaneko, Katsunori Yanai, Akinori Aomatsu, Keiji Hirai, Susumu Ookawara, Kenichi Ishibashi, Yoshiyuki Morishita   +7 more
doaj   +1 more source

Macrophage Phenotype and Fibrosis in Diabetic Nephropathy

International Journal of Molecular Sciences, 2020
Diabetic nephropathy (DN) is the leading cause of end-stage renal disease globally. The primary initiating mechanism in DN is hyperglycemia-induced vascular dysfunction, but its progression is due to different pathological mechanisms, including oxidative
Priscila Calle, G. Hotter
semanticscholar   +1 more source

MicroRNA and Microvascular Complications of Diabetes

International Journal of Endocrinology, 2018
In the last decade, miRNAs have received substantial attention as potential players of diabetes microvascular complications, affecting the kidney, the retina, and the peripheral neurons. Compelling evidence indicates that abnormally expressed miRNAs have
F. Barutta, S. Bellini, R. Mastrocola, G. Bruno, G. Gruden   +4 more
doaj   +1 more source

Study on the Mechanism of Coptis Chinensis in the Treatment of Diabetic Nephropathy Based on Network Pharmacology [PDF]

BIO Web of Conferences, 2023
To investigate the therapeutic effects of Coptis chinensis on diabetic nephropathy using systematic pharmacological techniques. The TCMSP database was used to search the main components and related targets of Coptis chinensis; the GeneCards and CTD ...
Yu Cheng, Qian Liting, Chen Ying, Guan Jing, Jiang Shuang, Song Danning   +5 more
doaj   +1 more source

A Case of Rapidly Progressive Diabetic Nephropathy Induced by Osimertinib

Case Reports in Nephrology and Dialysis, 2023
The number of patients with diabetic nephropathy is increasing worldwide and it is important to understand the underlying pathological mechanisms of the disease.
Kazunori Karasawa, Ken-ichi Akiyama, Taro Akihisa, Yoei Miyabe, Kosaku Nitta, Junichi Hoshino   +5 more
doaj   +1 more source