Results 21 to 30 of about 845,031 (279)

Early detection of diabetic nephropathy in patient with type 2 diabetes mellitus: A review of the literature

Diabetes & vascular disease research, 2021
Type 2 diabetes mellitus is a pathology of heterogeneous etiology characterized by hyperglycemia resulting from lack of insulin action, insulin secretion, or both, and the population with diabetes mellitus is predicted to be about 439 million worldwide ...
Sopida Thipsawat
semanticscholar   +1 more source

An updated overview of diabetic nephropathy: Diagnosis, prognosis, treatment goals and latest guidelines

Diabetes, obesity and metabolism, 2020
Diabetic nephropathy (DN) is a major healthcare challenge. It occurs in up to 50% of those living with diabetes, is a major cause of end‐stage kidney disease (ESKD) that requires treatment with dialysis or renal transplantation, and is associated with ...
N. Selby, M. Taal
semanticscholar   +1 more source

Flavonoids on diabetic nephropathy: advances and therapeutic opportunities

Chinese Medicine, 2021
With the advances in biomedical technologies, natural products have attracted substantial public attention in the area of drug discovery. Flavonoids are a class of active natural products with a wide range of pharmacological effects that are used for the
Qichao Hu, Cai Qu, Xiaolin Xiao, Wenwen Zhang, Yinxiao Jiang, Zhao Wu, Dan Song, Xi Peng, Xiao Ma, Yanling Zhao   +9 more
semanticscholar   +1 more source

Antiinflammatory Actions of Klotho: Implications for Therapy of Diabetic Nephropathy

International Journal of Molecular Sciences, 2021
Klotho was initially introduced as an antiaging molecule. Klotho deficiency significantly reduces lifespan, and its overexpression extends it and protects against various pathological phenotypes, especially renal disease.
M. Typiak, A. Piwkowska
semanticscholar   +1 more source

The relationship between melatonin level and antioxidant enzymes in diabetic patients with and without nephropathy

Baghdad Journal of Biochemistry and Applied Biological Sciences, 2023
Background and objective: Diabetes is the most common cause of chronic renal disease globally. Diabetic nephropathy (DN) is one of the most serious consequences of type 2 diabetes.
Asaad Al-Khafaji, Seyed M. Mir, Fatemeh Mohammadzadeh, Maryam Abolghasemi, Mahmoud H. Hadwan   +4 more
doaj   +1 more source

Dietary Fiber Protects against Diabetic Nephropathy through Short-Chain Fatty Acid-Mediated Activation of G Protein-Coupled Receptors GPR43 and GPR109A.

Journal of the American Society of Nephrology, 2020
BACKGROUND Studies have reported "dysbiotic" changes to gut microbiota, such as depletion of gut bacteria that produce short-chain fatty acids (SCFAs) through gut fermentation of fiber, in CKD and diabetes.
Y. Li, Xiaochen Chen, Tony K Kwan, Y. Loh, J. Singer, Yunzi Liu, Jin Ma, Jian Tan, L. Macia, C. Mackay, S. Chadban, Hui-ling Wu   +11 more
semanticscholar   +1 more source

Hyperglycemia and Hyperlipidemia Act Synergistically to Induce Renal Disease in LDL Receptor-Deficient BALB Mice [PDF]

, 2004
Diabetic nephropathy is the leading cause of end-stage renal disease in Western countries, but only a portion of diabetic patients develop diabetic nephropathy.
Alpers, Charles E., Hudkins, Kelly L., Kirk, Elizabeth, LeBoeuf, Renée C., Mühlfeld, Anja S., Segerer, Stephan, Spencer, Min W.   +6 more
core   +1 more source

Genome-wide DNA methylation analysis for diabetic nephropathy in type 1 diabetes mellitus [PDF]

, 2010
BACKGROUND: Diabetic nephropathy is a serious complication of diabetes mellitus and is associated with considerable morbidity and high mortality.
A Buja, A Helgadottir, A Subramanian, AE Teschendorff, Alexander P Maxwell, Andrew E Teschendorff, AS O'Connor, B He, B Krause, BH Ramsahoye, C Weigert, Christopher G Bell, D Ansell, D Ingrosso, DA Tregouet, David A Savage, EJ Richards, ER Seaquist, F Eckhardt, G Lund, H Al-Kateb, H Makino, HN Ibrahim, JD Storey, JF Navarro-Gonzalez, JJ Rogus, JT Leek, K Ichinose, M Bibikova, M Bibikova, M Quinn, MG Pezzolesi, MG Pezzolesi, MM Suzuki, MP Turunen, NM Goldenberg, P Katavetin, R Ihaka, R Lister, R Sladek, RA Irizarry, RC Gentleman, S Beck, S Saxonov, Stephan Beck, T Hastie, TA Down, TJ Ekstrom, TS Leak, U.S Renal Data System, Vardhman K Rakyan   +50 more
core   +4 more sources

Macrophage Phenotype and Fibrosis in Diabetic Nephropathy

International Journal of Molecular Sciences, 2020
Diabetic nephropathy (DN) is the leading cause of end-stage renal disease globally. The primary initiating mechanism in DN is hyperglycemia-induced vascular dysfunction, but its progression is due to different pathological mechanisms, including oxidative
Priscila Calle, G. Hotter
semanticscholar   +1 more source

Clinical correlation of diabetic retinopathy with nephropathy and neuropathy

Indian Journal of Ophthalmology, 2021
Purpose: To evaluate the presence of nephropathy and neuropathy in patients with diabetic retinopathy (DR) and to correlate the severity of DR to that of diabetic nephropathy and diabetic neuropathy.
Deepti Saini, A. Kochar, R. Poonia
semanticscholar   +1 more source