MicroRNAs in Podocyte Injury in Diabetic Nephropathy
Frontiers in Genetics, 2020 Diabetic nephropathy is one of the major complications of diabetes mellitus and is the leading cause of end-stage renal disease worldwide. Podocyte injury contributes to the development of diabetic nephropathy.
Hiroki Ishii +7 more
doaj +1 more source
Dietary interventions to contrast the onset and progression of diabetic nephropathy. a critical survey of new data [PDF]
, 2017 This article is a critical overview of recent contributions on the dietary corrections and the foods that have been claimed to delay or hinder the onset of diabetic nephropathy (DN) and its progression to end-stage renal disease.
Iacobini, Carla +3 more
core +1 more source
Inflammatory Targets in Diabetic Nephropathy
Journal of Clinical Medicine, 2020 One of the most frequent complications in patients with diabetes mellitus is diabetic nephropathy (DN). At present, it constitutes the first cause of end stage renal disease, and the main cause of cardiovascular morbidity and mortality in these patients.
J. Donate-Correa +8 more
semanticscholar +1 more source
MicroRNA and Microvascular Complications of Diabetes
International Journal of Endocrinology, 2018 In the last decade, miRNAs have received substantial attention as potential players of diabetes microvascular complications, affecting the kidney, the retina, and the peripheral neurons. Compelling evidence indicates that abnormally expressed miRNAs have
F. Barutta +4 more
doaj +1 more source
A Case of Rapidly Progressive Diabetic Nephropathy Induced by Osimertinib
Case Reports in Nephrology and Dialysis, 2023 The number of patients with diabetic nephropathy is increasing worldwide and it is important to understand the underlying pathological mechanisms of the disease.
Kazunori Karasawa +5 more
doaj +1 more source
Proteomics for prediction of disease progression and response to therapy in diabetic kidney disease [PDF]
, 2016 The past decade has resulted in multiple new findings of potential proteomic biomarkers of diabetic kidney disease (DKD). Many of these biomarkers reflect an important role in the (patho)physiology and biological processes of DKD.
Heerspink, Hiddo J.L. +2 more
core +2 more sources
Urinary peptidomics analysis reveals proteases involved in diabetic nephropathy [PDF]
, 2017 Mechanisms underlying the onset and progression of nephropathy in diabetic patients are not fully elucidated. Deregulation of proteolytic systems is a known path leading to disease manifestation, therefore we hypothesized that proteases aberrantly ...
Bascands, Jean-Loup +15 more
core +2 more sources
High glucose up-regulates ENaC and SGK1 expression in HCD-cells [PDF]
, 2006 Background/Aim: Diabetic nephropathy is associated with progressive renal damage, leading to impaired function and end-stage renal failure. Secondary hypertension stems from a deranged ability of cells within the kidney to resolve and appropriately ...
Bell LM +30 more
core +1 more source
Long-term glycemic variability and risk of adverse outcomes: a systematic review and meta-analysis [PDF]
, 2015 OBJECTIVE: Glycemic variability is emerging as a measure of glycemic control, which may be a reliable predictor of complications. This systematic review and meta-analysis evaluates the association between HbA1c variability and micro- and macrovascular ...
Catherine Gorst +18 more
core +1 more source
Diabetic kidney disease. new clinical and therapeutic issues. Joint position statement of the Italian Diabetes Society and the Italian Society of Nephrology on "the natural history of diabetic kidney disease and treatment of hyperglycemia in patients with type 2 diabetes and impaired renal function" [PDF]
, 2019 Recent epidemiological studies have disclosed heterogeneity in diabetic kidney disease (DKD). In addition to the classical albuminuric phenotype, two new phenotypes have emerged, i.e., “nonalbuminuric renal impairment” and “progressive renal decline ...
Barutta, Federica +7 more
core +1 more source