Results 31 to 40 of about 753,615 (353)

FABP1 and FABP2 as markers of diabetic nephropathy

International Journal of Medical Sciences, 2020
Background: Diabetes mellitus is the leading cause of diabetic nephropathy and a major public health issue worldwide. Approximately 20-30% of patients with type 2 diabetes mellitus (T2DM) have renal impairment.
I-Ting Tsai, Cheng-Ching Wu, W. Hung, Thung-Lip Lee, Chin-Feng Hsuan, Ching-Ting Wei, Yung-Chuan Lu, Teng-Hung Yu, Fu-Mei Chung, Yau-Jiunn Lee, Chao-Ping Wang   +10 more
semanticscholar   +1 more source

The single-cell transcriptomic landscape of early human diabetic nephropathy

Proceedings of the National Academy of Sciences of the United States of America, 2019
Significance Single-nucleus RNA sequencing revealed gene expression changes in early diabetic nephropathy that promote urinary potassium secretion and decreased calcium and magnesium reabsorption.
Parker C. Wilson, Haojia Wu, Y. Kirita, Kohei Uchimura, Nicolas Ledru, H. Rennke, P. Welling, S. Waikar, B. Humphreys   +8 more
semanticscholar   +1 more source

Awareness of diabetic nephropathy in patients with type 2 diabetes mellitus: the Indian scenario [PDF]

Journal of Nephropharmacology, 2018
Introduction: Diabetic nephropathy is an important complication of diabetes mellitus leading to significant morbidity and mortality. Objectives: To study the awareness of diabetic nephropathy in patients with type 2 diabetes mellitus (T2DM) and the ...
Chirag Bansal, Reshma Kaushik, Rajeev Mohan Kaushik   +2 more
doaj  

Natural coumarins: Preclinical evidence-based potential candidates to alleviate diabetic nephropathy

Phytomedicine Plus, 2022
Background: Cis-o-hydroxycinnamic acid lactones, referred to as natural coumarin, have a basic skeleton of benzopyranone in their structure. The natural coumarins are typically found abundantly in roots, rhizomes, bark, and leaves of the plant belonging ...
Sitara Ghosh, Ankana Ghosh, Ashitha Rajanan, Amal Jyothy Suresh, Pratiksha Sharadrao Raut, Sourav Kundu, Bidya Dhar Sahu   +6 more
doaj  

Recent Advances of Metformin in Treatment of Diabetic Nephropathy [PDF]

Zhongguo quanke yixue
Diabetic nephropathy is one of the most common complications of diabetic microangiopathy, which significantly reduces the quality of life of diabetic patients and is the main cause of end-stage renal failure.
DENG Yuxuan, HUANG Xuejun, JIANG Yanxia
doaj   +1 more source

Incidence of Diabetic Nephropathy and Its Predictors among Type 2 Diabetes Mellitus Patients at University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia

Journal of Nutrition and Metabolism, 2021
Background. Although the rate of diabetic nephropathy which is the leading cause of end-stage renal disease (ESRD) continues to rise, there is limited information about the problem.
Sewnet Adem Kebede, Biruk Shalmeno Tusa, Adisu Birhanu Weldesenbet, Zemenu Tadesse Tessema, Tadesse Awoke Ayele   +4 more
doaj   +1 more source

The Role of Diacylglycerol Kinase in the Amelioration of Diabetic Nephropathy

Molecules, 2022
The drastic increase in the number of patients with diabetes and its complications is a global issue. Diabetic nephropathy, the leading cause of chronic kidney disease, significantly affects patients’ quality of life and medical expenses.
Daiki Hayashi, Yasuhito Shirai
doaj   +1 more source

Update on Diabetic Nephropathy: Core Curriculum 2018.

American Journal of Kidney Diseases, 2018
Diabetic kidney disease and diabetic nephropathy are the leading cause of end-stage kidney disease in the United States and most developed countries. Diabetes accounts for 30% to 50% of the incident cases of end-stage kidney disease in the United States.
K. Umanath, J. Lewis
semanticscholar   +1 more source

Analysis of Urine Podocalyxin in Type 2 Diabetes Mellitus Subjects With and Without Diabetic Nephropathy

Indonesian Journal of Medical Laboratory Science and Technology, 2023
Type 2 diabetes mellitus is the most common cause of diabetes, consist from about 85% of cases. Diabetic nephropathy is a complication of diabetes mellitus in the kidneys which can end up as kidney failure.
Jusni Ekasari Pelu, Liong Boy Kurniawan, Yuyun Widaningsih, Alfian Zainuddin, Husaini Umar, Nurahmi Nurahmi, Theosobia Grace Orno   +6 more
doaj   +1 more source

The Role of Autophagy in the Pathogenesis of Diabetic Nephropathy

Journal of Diabetes Research, 2013
Diabetic nephropathy is a leading cause of end-stage renal disease worldwide. The multipronged drug approach targeting blood pressure and serum levels of glucose, insulin, and lipids fails to fully prevent the onset and progression of diabetic ...
Kosuke Yamahara, Mako Yasuda, Shinji Kume, Daisuke Koya, Hiroshi Maegawa, Takashi Uzu   +5 more
doaj   +1 more source