Glomerular mesangial cell and podocyte injuries in diabetic nephropathy
Diabetic nephropathy is one of the leading causes of end‐stage renal disease and creates heavy healthcare burdens globally. Dysfunction of mesangial cells and podocytes contributes to diabetic nephropathy.
Chun-Wu Tung +4 more
semanticscholar +1 more source
Potensi Kedelai sebagai Nutrisiuntuk Pencegahan Nefropati Diabetes pada Penderita Diabetes Melitus
Diabetes mellitus is the fourth of five causes of death in developed countries . This trend extends to developing countries and newly industrialized countries .
Putri Dafriani
doaj +1 more source
Functional expression of TRPV4 channels in human collecting duct cells: implications for secondary hypertension in diabetic nephropathy [PDF]
Background. The Vanilloid subfamily of transient receptor potential (TRPV) ion channels has been widely implicated in detecting osmotic and mechanical stress.
Bland, Rosemary +2 more
core +3 more sources
Guangxu Liu,1,2 Jingtao Dou,3,4 Deqiang Zheng,1,2 Jie Zhang,1,2 Meiping Wang,1,2 Wei Li,1,2 Jing Wen,1,2 Juming Lu,3 Linong Ji,5 Yan He1,2 1Department of Epidemiology and Biostatistics, School of Public Health, Capital Medical University, Beijing, People&
Liu G +9 more
doaj
Proteomic prediction and Renin angiotensin aldosterone system Inhibition prevention Of early diabetic nephRopathy in TYpe 2 diabetic patients with normoalbuminuria (PRIORITY): essential study design and rationale of a randomised clinical multicentre trial [PDF]
Introduction: Diabetes mellitus affects 9% of the European population and accounts for 15% of healthcare expenditure, in particular, due to excess costs related to complications.
Beige, Joachim +14 more
core +4 more sources
Fractalkine in type 2 Egyptian diabetics with and without nephropathy
Background Diabetes mellitus is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both.
Ebtissam Zakaria +4 more
doaj +1 more source
Chemical composition, antioxidant and alpha-Glucosidase-Inhibiting activities of the aqueous and hydroethanolic extracts of Vaccinium myrtillus Leaves [PDF]
Vaccinium myrtillus (bilberry) leaf is traditionally used in southeastern Europe for the treatment of diabetes. In the present study, the ability of bilberry leaf extracts to inhibit carbohydrate-hydrolyzing enzymes and restore glutathione concentration ...
Bljajic, Kristina +7 more
core +1 more source
Angiopoietins and diabetic nephropathy [PDF]
Diabetic nephropathy is the main cause of end-stage renal failure in the Western world. In diabetes, metabolic and haemodynamic perturbations disrupt the integrity of the glomerular filtration barrier, leading to ultrastructural alterations of the glomeruli, including podocyte foot process fusion and detachment, glomerular basement membrane thickening,
openaire +6 more sources
The Role of MicroRNAs in the Pathogenesis of Diabetic Nephropathy
Diabetic nephropathy (DN) is one of the most common microvascular complications in diabetic patients; it is also an important cause of renal dysfunction, renal fibrosis, and end-stage renal disease.
Jian Tang +5 more
semanticscholar +1 more source
The influence of a single nucleotide polymorphism within CNDP1 on susceptibility to diabetic nephropathy in Japanese women with type 2 diabetes. [PDF]
BACKGROUND: Several linkage analyses have mapped a susceptibility locus for diabetic nephropathy to chromosome 18q22-23, and polymorphisms within the carnosine dipeptidase 1 gene (CNDP1), located on 18q22.3, have been shown to be associated with diabetic
Mahiro Kurashige +14 more
doaj +1 more source

