Results 91 to 100 of about 28,020 (301)
In a large cohort of patients with newly diagnosed transthyretin amyloid cardiomyopathy (ATTR‐CM), echocardiographic apical sparing was associated with increased left ventricular amyloid load and atrial remodelling. Quantitative biopsy analysis revealed that Perugini scores often failed to accurately reflect myocardial amyloid burden.
Thomas Krammer +21 more
wiley +1 more source
Diabetic osteoarthropathy: modern methods of therapy
This paper is focused on the main aspects of pathogenesis of diabetic osteoarthropathy (DOAP) underlain by motor and sensory neuropathies, injuries(including microfractures and joint disintegration), and inflammation accompanied by enhanced cytokine ...
Irina N. Ul'yanova +4 more
doaj +1 more source
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons +17 more
wiley +1 more source
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley +1 more source
Multidisciplinary valuation of the diabetic foot [PDF]
Conventional classifications for diabetic foot, among them, Wagner Classification, do not contemplate the criteria or sichemia, neuropathy and infection, pillars that sustain the etiopathogy of this syndrome.
Isabel Sánchez Reyes +5 more
doaj
Effect of Glycemic Variability on Peripheral Neuropathy in Patients with Type-2 Diabetes
About 75% of diabetic neuropathies are distal symmetrical sensorimotor polyneuropathy (DSPN), among the most frequent preventable causes of limb amputation.
Saba Zaidi
doaj +1 more source
What's New? New antibody‐drug conjugates (ADCs) and immunotherapies have helped expand treatment options for urothelial carcinoma (UC). Clinical trials suggest that the ADC enfortumab vedotin (EV) and the immunotherapeutic agent pembrolizumab, when used in combination, are especially effective against UC.
Dora Niedersuess‐Beke +30 more
wiley +1 more source

