Results 111 to 120 of about 14,501 (284)

KNOWLEDGE OF PATIENTS WITH DIABETES MELLITUS ABOUT DIABETES NEUROPATHY SYMPTOMS

Nurse and Health
Background: Diabetes Mellitus (DM) is a metabolic disease characterized by high blood glucose levels or hyperglycemia, which in the long term can cause complications both macrovascular and microvascular.
Anita Joeliantina, Sintya Zahratul, Nur Hasanah, Sri Hardi Wuryaningsih, Endang Soelistyowati   +4 more
doaj   +1 more source

Metabolomics in Pathogenic Pathways and Targeted Therapies for Diabetic Neuropathy: A Comprehensive Review

Metabolites
Introduction and objective: This literature review aims to provide an overview of the progress in metabolomic assessment in animal and cell models and in humans with diabetic neuropathy (DN). Methods: Metabolomics has emerged as an important approach for
Cornelia Bala, Adriana Rusu, Dana Mihaela Ciobanu, Gabriela Roman, Anca Elena Crăciun   +4 more
doaj   +1 more source

Pharmacological effects of gastrodin: Insight into neurological diseases and mechanism in ferroptosis and pyroptosis

Ibrain, Volume 11, Issue 1, Page 74-83, Spring 2025.
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley   +1 more source

Deterioration in ankle reflex is associated with a reduced estimated glomerular filtration rate in patients with type 2 diabetes: A retrospective observational cohort study

Journal of Diabetes Investigation
Aims/Introduction We investigated the association between the ankle reflex and the estimated glomerular filtration rate (eGFR) in patients with type 2 diabetes. Materials and Methods This was a single‐center, retrospective, observational cohort study.
Taichi Muramatsu, Daisuke Yamamuro, Akifumi Kushiyama, Takako Kikuchi   +3 more
doaj   +1 more source

Synthesized flavone attenuates diabetes‐induced neurodegeneration through regulation of oxidative stress and metabolic‐neurodegenerative molecular pathways

Ibrain, EarlyView.
Neuroprotective efficacy of flavone (2‐phenyl‐4H‐chromen‐4‐one). The study aimed to explore the potential of a synthetic derivative (flavone) of a phytocompound, which is involved in neuroprotection activities. Experimental strategies included the characteristics of compound, in‐silico analysis, and in vivo assessments.
Karishma Sen, Anita Sakarwal, Heera Ram, Suman K. Saha, Nirmal K. Rana, Dharmveer Yadav, Sunil Dutt Shukla, Mukesh Kumar Yadav, Balachandar Vellingiri, Vikas Kumar   +9 more
wiley   +1 more source

Role of 12/15-lipoxygenase in nitrosative stress and peripheral prediabetic and diabetic neuropathies

, 2010
This study evaluated the role of 12/15-lipoxygenase, which converts arachidonic acid to 12(S)- and 15(S)-hydroxyeicosatetraenoic acids, in nitrosative stress in the peripheral nervous system and peripheral prediabetic and diabetic neuropathies.
Viktor R. Drel, Igor Vareniuk, Hanna Shevalye, Roman Stavniichuk, Martin J. Stevens, Nadler, JL, Obrosova, IG, Stevens, Martin, Irina G. Obrosova, Shevalye, H, Vareniuk, I, Jerry L. Nadler, Drel, VR, Stavniichuk, R   +13 more
core   +1 more source

Effect of Glycemic Variability on Peripheral Neuropathy in Patients with Type-2 Diabetes

Pakistan Journal of Medicine and Dentistry
About 75% of diabetic neuropathies are distal symmetrical sensorimotor polyneuropathy (DSPN), among the most frequent preventable causes of limb amputation.
Saba Zaidi
doaj   +1 more source

Multidisciplinary valuation of the diabetic foot [PDF]

NURE Investigación, 2010
Conventional classifications for diabetic foot, among them, Wagner Classification, do not contemplate the criteria or sichemia, neuropathy and infection, pillars that sustain the etiopathogy of this syndrome.
Isabel Sánchez Reyes, Rafael Jorge Pérez Pérez, Jose Manuel Hernández Romero, Mª Jesús Martín González, Alfredo Castro Díaz, Rocío López Cueto   +5 more
doaj  

Somatosensory Disturbance and Long‐Term Exposure to Methylmercury: A Comprehensive Review

Journal of Applied Toxicology, EarlyView.
ABSTRACT Chronic exposure to methylmercury remains a significant public health concern, particularly in populations with high fish consumption. Somatosensory disturbances are among the most frequently reported neurological manifestations, even at exposure levels below internationally established safety thresholds. This review aims to synthesize current
Leonardo Breno do Nascimento de Aviz, Carolina Fonte de Aviz, Fabiana Costa Cardoso, Laura dos Santos Barros, Raphaely Cristiny Sanches Progênio, Mariângela Moreno Domingues, José Maria Farah Costa Júnior, Saul Rassy Carneiro, Carlos Araújo da Costa, Maria da Conceição Nascimento Pinheiro   +9 more
wiley   +1 more source

Diabetic peripheral neuropathy, is it an autoimmune disease?

, 2015
Background: Autoimmunity has been identified in a significant number of neuropathies, such as, proximal neuropathies, and autonomic neuropathies associated with diabetes mellitus.
Blyth, Christine, Bakhiet, Moiz, Ellis, Mairghread JH, Janahi, Noor M., Santos, Derek   +4 more
core   +1 more source