Results 121 to 130 of about 412,873 (280)
Mass Spectrometry Reviews, EarlyView.ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley +1 more source
Syndromic Mitochondrial Optic Neuropathies
, 2012 In some of the hereditary optic neuropathies, optic nerve dysfunction is typically isolated. In others, various neurologic and systemic abnormalities are regularly observed.IC-E2dii5-other-mitochondrial ...
Nancy J. Newman, MD
core
How to assess new drugs for neuropathies: advances in trial design and methodology
, 2008 Purpose of review New randomized controlled trials are very much needed to improve the outcome in patients with a variety of peripheral neuropathies.
van Doorn, Pieter; id_orcid +1 more
core +1 more source
Prevalence and Associations of Abnormal Levels of Vitamin B6 in People with Parkinson's Disease
Movement Disorders Clinical Practice, EarlyView.Abstract Background In people with Parkinson's disease, abnormal levels of vitamin B6 may be associated with polyneuropathy and epileptic seizures, including medication‐refractory status epilepticus. Objectives To estimate the prevalence and explore associations of abnormal levels of vitamin B6 in people with Parkinson's disease.
Karlo J. Lizarraga +7 more
wiley +1 more source
Parkinson's Disease and Retinal Age Gap: A Cross‐Sectional Analysis
Movement Disorders, EarlyView.Abstract Background Deep‐learning models are capable of predicting age from retinal scans and the difference between this and chronological age, retinal age gap, has been shown to be significantly associated with risk of mortality, cardiovascular diseases, and kidney failure.
Akshay Narayan +9 more
wiley +1 more source
Early and Extensive Degeneration of Sensory Neurons in Spinocerebellar Ataxia Type 3
Movement Disorders, EarlyView.Abstract Background Postmortem studies have shown significant degeneration of the peripheral nervous system (PNS) in spinocerebellar ataxia type 3 (SCA3). Although PNS involvement accelerates overall ataxia progression, PNS biomarkers for therapeutic trials are lacking and our mechanistic understanding of related clinical manifestations remains ...
Milou Baarsma +3 more
wiley +1 more source
Journal of DiabetologyBackground: Diabetic peripheral neuropathy (DPN) is a prevalent and debilitating complication of diabetes mellitus (DM) that is frequently diagnosed at an advanced stage, when substantial nerve damage is irreversible.
Rayam Abd Al Kareem Zaidan +1 more
doaj +1 more source
Carpal Tunnel Release in Super‐Elderly: Safety Profile and Clinical Outcomes
Medicine Advances, EarlyView.A retrospective review between a super‐elderly cohort (age > 80 years, n = 18) and control group (age 50–54 years, n = 22) showed comparable incidence of pillar pain, scar pain, grip power, symptom improvement, and patient satisfaction score. Lower mean Functional Status Scale of Boston Carpal Tunnel Questionnaire was observed in the super‐elderly ...
Chloe Wing Shuen Lam +2 more
wiley +1 more source
Health Science ReportsBackground and Aim Globally, diabetes mellitus is a major public health concern affecting 10.5% of the population. Nearly 90% of these people have Type 2 diabetes mellitus (T2DM). In Bhutan, T2DM is prevalent in 5.6% of the population, and around 60% are
Tshering Norbu +4 more
doaj +1 more source
Repurposing antimicrobial agents for neuroprotection: Mechanisms, clinical potential, and challenges
Neuroprotection, EarlyView.Antimicrobial agents exert neuroprotective effects through modulation of interconnected pathways. Tetracyclines, macrolides, antimalarial agents, sulfones, and antiparasitic agents suppress neuroinflammation, oxidative stress, and apoptosis while preserving mitochondrial function and neurotransmission.
Mohammad Amin Manavi +5 more
wiley +1 more source