Results 131 to 140 of about 23,070 (296)

Effect of Glycemic Variability on Peripheral Neuropathy in Patients with Type-2 Diabetes

Pakistan Journal of Medicine and Dentistry
About 75% of diabetic neuropathies are distal symmetrical sensorimotor polyneuropathy (DSPN), among the most frequent preventable causes of limb amputation.
Saba Zaidi
doaj   +1 more source

Multidisciplinary valuation of the diabetic foot [PDF]

NURE Investigación, 2010
Conventional classifications for diabetic foot, among them, Wagner Classification, do not contemplate the criteria or sichemia, neuropathy and infection, pillars that sustain the etiopathogy of this syndrome.
Isabel Sánchez Reyes, Rafael Jorge Pérez Pérez, Jose Manuel Hernández Romero, Mª Jesús Martín González, Alfredo Castro Díaz, Rocío López Cueto   +5 more
doaj  

Pharmacological effects of gastrodin: Insight into neurological diseases and mechanism in ferroptosis and pyroptosis

Ibrain, Volume 11, Issue 1, Page 74-83, Spring 2025.
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley   +1 more source

Synthesized flavone attenuates diabetes‐induced neurodegeneration through regulation of oxidative stress and metabolic‐neurodegenerative molecular pathways

Ibrain, EarlyView.
Neuroprotective efficacy of flavone (2‐phenyl‐4H‐chromen‐4‐one). The study aimed to explore the potential of a synthetic derivative (flavone) of a phytocompound, which is involved in neuroprotection activities. Experimental strategies included the characteristics of compound, in‐silico analysis, and in vivo assessments.
Karishma Sen, Anita Sakarwal, Heera Ram, Suman K. Saha, Nirmal K. Rana, Dharmveer Yadav, Sunil Dutt Shukla, Mukesh Kumar Yadav, Balachandar Vellingiri, Vikas Kumar   +9 more
wiley   +1 more source

Spectrum of diabetic neuropathies. [PDF]

Diabetol Int, 2020
Sasaki H, Kawamura N, Dyck PJ, Dyck PJB, Kihara M, Low PA.   +5 more
europepmc   +1 more source

Systemic anti‐cancer therapy associated with the occurrence of peripheral neurotoxicity and, specifically, peripheral neuropathy

International Journal of Cancer, EarlyView.
What's New? While the effectiveness of systemic anticancer therapy is well documented, it commonly causes severe toxicity. This study of the 467 systemic anticancer therapy agents currently approved globally for clinical and/or research purposes found that peripheral neurotoxicity is associated with 45% of classical chemotherapies, 21% of targeted ...
Cassie Higgins, Lynn R. Gauthier, Blair H. Smith, Lesley Colvin   +3 more
wiley   +1 more source

Optimization of bioactive compounds extraction from Rosa canina L. pseudofruit through the action of two hydrolytic enzyme preparations

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKROUND The pseudo‐fruit of Rosa canina L. is a rich source of bioactive compounds with antioxidant, anti‐inflammatory, anti‐cancer, anti‐diabetic, anti‐aging, and antimicrobial activities. The aim of the present study is the optimization of a green process based on the action of two hydrolytic enzyme preparations, namely Pectinex® Ultra ...
Zafeiria Lemoni, Styliani Kalantzi, Theopisti Lymperopoulou, Andromachi Tzani, Georgios Stavropoulos, Anastasia Detsi, Diomi Mamma   +6 more
wiley   +1 more source

Things We Do for No Reason™: Prescribing gabapentinoids for pain

Journal of Hospital Medicine, EarlyView.
Abstract Gabapentin and pregabalin are among the most frequently prescribed medications in the United States, with gabapentin in the top 10 and pregabalin in the top 100. Despite FDA approval for only select neuropathic conditions, most use is for off‐label pain indications.
Niti G. Patel, David Goese, Steven M. Belknap, Charles L. Madeira, Jeffrey H. Barsuk   +4 more
wiley   +1 more source

Impact of severe periodontitis and diabetes mellitus on recurrent cardiovascular outcomes

Journal of Periodontology, EarlyView.
Abstract Background This post hoc analysis of the Periodontitis and Coronary Heart Disease study (ClinicalTrials.gov Identifier: NCT01045070) aimed to determine the association between diabetes and recurrent cardiovascular events (CVEs) in patients with cardiovascular disease (CVD) and severe periodontitis.
Stefan Reichert, Axel Schlitt, Selina Rehm, Susanne Schulz   +3 more
wiley   +1 more source

Association between periodontitis and oral health–related quality of life in patients with systemic conditions: A meta‐analysis

Journal of Periodontology, EarlyView.
Abstract Background The objective of this systematic review is to evaluate whether periodontitis is associated with impaired oral health–related quality of life (OHRQoL) in adults with systemic conditions. Methods Five databases were searched to identify observational studies that tested the association between periodontitis (diagnosed by clinical ...
Rafael Vargas Bortolaso, Catiusse Crestani Del' Agnese, Leandro Machado Oliveira, Patricia A. Miguez, Fabricio Batistin Zanatta, Raquel Pippi Antoniazzi   +5 more
wiley   +1 more source