Results 111 to 120 of about 38,385 (346)

Comparison of efficacy and tolerability of Duloxetine vs. Gabapentin in treatment of diabetic peripheral neuropathic pain [PDF]

open access: yes, 2011
Introduction: Diabetic peripheral neuropathy (DPN) is one of the most common symptomatic, long-term complications in patients with both type 1 and type 2 diabetes mellitus, and most common and most debilitating of the diabetic neuropathies. Duloxetine,
Kalantar Hormozi, Mohamadreza   +3 more
core  

Safety and pharmacokinetics of a novel potent GABA analogue crisugabalin in Chinese subjects with various degrees of renal impairment

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Crisugabalin is a novel calcium channel α2δ subunit ligand and a highly selective oral gamma‐aminobutyric acid (GABA) analogue developed for the treatment of diabetic peripheral neuropathic pain (DPNP) and postherpetic neuralgia (PHN). This study investigated pharmacokinetic properties and safety of crisugabalin in subjects with renal impairment ...
Shibeilei Lin   +6 more
wiley   +1 more source

Decreased microstructural integrity of the central somatosensory tracts in diabetic peripheral neuropathy

open access: gold, 2021
Fang Fang   +10 more
openalex   +1 more source

Cutting edge strategies for diabetic wound care: Nanotechnology, bioengineering, and beyond

open access: yesBMEMat, EarlyView.
Graphical abstract illustrates the challenges in diabetic wound healing, covering pathophysiology, formulation hurdles, and emerging therapeutic strategies. It highlights the role of hyperglycemia, formulation complexities, and advanced technologies like bioprinting and AI in improving diabetic wound management. Abstract Diabetic wounds affect millions
Usama Ahmad   +8 more
wiley   +1 more source

Current status and future directions of botulinum neurotoxins for targeting pain processing. [PDF]

open access: yes, 2015
Current evidence suggests that botulinum neurotoxins (BoNTs) A1 and B1, given locally into peripheral tissues such as skin, muscles, and joints, alter nociceptive processing otherwise initiated by inflammation or nerve injury in animal models and humans.
Pellett, Sabine   +2 more
core   +2 more sources

Copper‐doped borosilicate bioactive glass coating modified bacterial cellulose functional dressing for diabetic ulcer

open access: yesBMEMat, EarlyView.
For the first time, a borosilicate‐based bioactive glass coating was successfully formed on the surface of bacterial cellulose nanofibers. A copper‐doped borosilicate bioactive glass coating‐modified bacterial cellulose functional dressing was designed for the management of chronic wounds, such as diabetic ulcers.
Haiyong Ao   +8 more
wiley   +1 more source

Predicting the Response to Intravenous Immunoglobulins in an Animal Model of Chronic Neuritis [PDF]

open access: yes, 2016
Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a disabling autoimmune disorder of the peripheral nervous system (PNS). Intravenous immunoglobulins (IVIg) are effective in CIDP, but the treatment response varies greatly between ...
Bendszus, Martin   +8 more
core   +2 more sources

Biomaterial design strategies for enhancing mitochondrial transplantation therapy

open access: yesBMEMat, EarlyView.
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang   +12 more
wiley   +1 more source

The conundrum of diabetic neuropathies-Past, present, and future. [PDF]

open access: yesJ Diabetes Complications, 2022
Ang L   +6 more
europepmc   +1 more source

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