Results 221 to 230 of about 115,506 (337)

Downregulation of microRNA‐494 drives mitochondrial biogenesis and function in trained muscle

open access: yesExperimental Physiology, EarlyView.
Abstract MicroRNAs (miRNAs) are key regulators of cellular processes, including mitochondrial function and energy metabolism. This study explores the regulation of miR‐494 in skeletal muscle and circulation, investigating its response to exercise training and an acute exercise bout, its association with metabolic disorders, and the effects of ...
Natália Pálešová   +10 more
wiley   +1 more source

Combined Weight Loss and Exercise Training Alters Skeletal Muscle Subcellular Lipid Localization and Intermuscular Adipose Tissue Cellular Composition. [PDF]

open access: yesDiabetes
Zemski Berry K   +19 more
europepmc   +1 more source

Lactate Dehydrogenase Inhibition Reverts the Fatty Acid‐Induced Neurotoxic Phenotype of Astrocytes

open access: yesGlia, Volume 74, Issue 3, March 2026.
ALS models display increased LD accumulation. LD accumulation is linked to a neurotoxic phenotype in astrocytes. Lactate dehydrogenase inhibition reverts LD accumulation in ALS astrocytes. ABSTRACT Astrocytes are central to lipid metabolism in the central nervous system.
Daniel Esteve   +5 more
wiley   +1 more source

A comparative study of the activation of protein kinase C α by different diacylglycerol isomers [PDF]

open access: bronze, 1999
Pilar Sánchez‐Piñera   +3 more
openalex   +1 more source

Aging‐Derived Alterations in Genomic, Immune, and Metabolic Networks: Implications for Cancer Development and Therapy

open access: yesMedComm – Oncology, Volume 5, Issue 1, March 2026.
Ageing acts as a double‐edged sword in cancer. In the elderly, open chromatin, immunosenescence, and chronic inflammation drive SASP (IL‐6, MMPs), MDSC accumulation and T‐cell suppression, fostering tumor‐promoting microenvironments and limited therapeutic benefit.
Qi Wang   +7 more
wiley   +1 more source

Plasma lipidomic patterns associated with disease activity in chronic inflammatory demyelinating polyradiculoneuropathy (LIPID-CIDP). [PDF]

open access: yesJ Lipid Res
Auf dem Brinke K   +7 more
europepmc   +1 more source

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