Results 91 to 100 of about 73,225 (285)
Signaling at the membrane interface by the DGK/SK enzyme family
Journal of Lipid Research, 2009 The sphingosine (SK) and diacylglycerol (DGK) kinases have become the subject of considerable focus recently due to their involvement as signaling enzymes in a variety of important biological processes.
Daniel M. Raben, Binks W. Wattenberg
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Second messenger systems underlying amine and peptide actions on cardiac muscle in the horseshoe crab, Limulus polyphemus [PDF]
, 1989 The biochemical mechanisms by which octopamine, catecholamines and the peptide proctolin exert their actions on Limulus cardiac muscle were investigated.
Groome, J. R., Watson, Winsor H., III
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Deep Transcriptomic Profiling of M1 Macrophages Lacking Trpc3 [PDF]
, 2017 In previous studies using mice with macrophage-specific loss of TRPC3 we found a significant, selective effect of TRPC3 on the biology of M1, or inflammatory macrophages.
Atolagbe, Oluwatomisin T. +5 more
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Food Frontiers, EarlyView.Sodium selenite or vitamin E supplementation enhances antioxidant defenses in mouse mammary glands, reducing oxidative stress, lipid peroxidation, and iron accumulation. This boosts GPX4 activity, inhibits PTGS2, and activates mTORC1, improving milk fat droplet formation and protein synthesis, with the combined treatment showing the greatest benefit ...
Qianzi Zhang +7 more
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Epigenetic regulation of diacylglycerol kinase alpha promotes radiation-induced fibrosis
Nature Communications, 2016 Radiotherapy can induce fibrosis in cancer patients, limiting its use in clinical settings. Here, the authors identify a differentially methylated enhancer of the lipid kinase DGKA in fibroblasts from breast cancer patients developing fibrosis after ...
Christoph Weigel +18 more
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Journal of Lipid Research, 1994 Ceramides and phospholipids constitute two important structural lipids of normal skin that are notably rich in polyunsaturated fatty acids. Although linoleic acid (LA) is high in the ceramides, the localization of its 15-lipoxygenase product, 13 ...
Y Cho, V A Ziboh
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Ks1, an epithelial cell-specific gene, responds to early signals of head formation in Hydra [PDF]
, 1994 As a molecular marker for head specification in Hydra, we have cloned an epithelial cell-specific gene which responds to early signals of head formation.
Bosch, Thomas C. G. +3 more
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Signaling pathways for transduction of the initial message of the glycocode into cellular responses [PDF]
, 1998 The sugar units of glycan structures store information and establish an alphabet of life. The language of the oligosaccharide coding units is deciphered by receptors such as lectins and the decoded message can be transduced by multiple signaling pathways.
Gabius, Hans-Joachim, Villalobo, A.
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Crystal structure of the integral membrane diacylglycerol kinase [PDF]
Nature, 2013 Diacylglycerol kinase catalyses the ATP-dependent phosphorylation of diacylglycerol to phosphatidic acid for use in shuttling water-soluble components to membrane-derived oligosaccharide and lipopolysaccharide in the cell envelope of Gram-negative bacteria.
David Aragão +12 more
openaire +6 more sources
The Influence of Schwann Cell Metabolism and Dysfunction on Axon Maintenance
Glia, EarlyView.Sensory neurons depend on Schwann cells for survival. Schwann cells provide energy for axons during rapid firing or after injury. Dysregulated metabolism in Schwann cells can lead to the production of neurotoxic lipids and axon degeneration. ABSTRACT Schwann cells are the glial cells in the peripheral nervous system responsible for the production of ...
Rose Follis +2 more
wiley +1 more source