Results 81 to 90 of about 441 (94)

Diacylglycerol, phosphatidic acid, and the converting enzyme, diacylglycerol kinase, in the nucleus

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2006
There exists phosphoinositide (PI) cycle in the nucleus, which is operated differentially from the classical PI cycle at the plasma membrane. Evidence has been accumulated that nuclear PIs and the related enzymes are closely involved in a variety of nuclear processes, although the details remain to be elucidated. In this mini review, some components of
Kaoru, Goto, Yasukazu, Hozumi, Hisatake, Kondo   +2 more
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Diacylglycerol kinases: at the hub of cell signalling

Biochemical Journal, 2007
DGKs (diacylglycerol kinases) are members of a unique and conserved family of intracellular lipid kinases that phosphorylate DAG (diacylglycerol), catalysing its conversion into PA (phosphatidic acid). This reaction leads to attenuation of DAG levels in the cell membrane, regulating a host of intracellular signalling proteins that have evolved the ...
Isabel, Mérida, Antonia, Avila-Flores, Ernesto, Merino   +2 more
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Diacylglycerol Kinases: Regulation and Signaling Roles

Thrombosis and Haemostasis, 2002
SummaryDiacylglycerol kinases (DGKs) are thought to attenuate diacylglycerol signals by converting diacylglycerol to phosphatidic acid. The nine mammalian diacylglycerol kinases that have been identified are widely expressed, but each isoform has a unique tissue and subcellular distribution.
Matthew K, Topham, Stephen M, Prescott
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Nuclear diacylglycerol kinases: regulation and roles

Frontiers in Bioscience, 2008
The diacylglycerol-kinases are a family of related lipid kinases. There are currently 10 known isoforms of diacylglycerol kinases that are categorized into five groups based on similarities in their primary sequence. All of these enzymes catalyze the transfer of the gamma-phosphate of ATP to one lipid second messenger, diacylglycerol, thereby ...
Daniel M, Raben, Becky, Tu-Sekine
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Inhibition of diacylglycerol kinases as a physiological way to promote diacylglycerol signaling

Advances in Biological Regulation, 2014
Diacylglycerol is a key regulator of cell physiology, controlling the membrane recruitment and activation of signaling molecules. Accordingly, diacylglycerol generation and metabolism are strictly controlled, allowing for localized regulation of its concentration.
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Diacylglycerol kinase

The International Journal of Biochemistry & Cell Biology, 1997
Fumio Sakane, Hideo Kanoh
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Regulation of diacylglycerol kinase by phosphorylation

Advances in Biological Regulation, 2012
Y, Shirai, M, Ikeda, N, Saito
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Diacylglycerol Kinases

2003
Matthew K. Topham, Steve M. Prescott
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Regulation and Functions of Diacylglycerol Kinases

Chemical Reviews, 2011
Yulia V, Shulga, Matthew K, Topham, Richard M, Epand   +2 more
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Regulation of ‘signalling diacylglycerol’ in cells: the importance of diacylglycerol kinase

Biochemical Society Transactions, 1996
M N, Hodgkin, T R, Pettitt, A, Martin, M J, Wakelam   +3 more
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