Results 111 to 120 of about 373,653 (317)
The diagnostic accuracy of two human epididymis protein 4 (HE4) testing systems in combination with CA125 in the differential diagnosis of ovarian masses [PDF]
, 2011 Background: Cancer antigen 125 (CA125) is the best known single tumor marker for ovarian cancer (OC). We investigated whether the additional information of the human epididymis protein 4 (HE4) improves diagnostic accuracy.
Fuerst, Sophie +19 more
core +1 more source
, 2023 Research on the impairment of episodic memory in AD usually treats all memory contents equally. However, recent studies have revealed that certain images are more diagnostic than other images in classifying whether a person may have AD or its precursors (
Bai, Yuetong
core +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Judging Quality and Coordination in Biomarker Diagnostic Development [PDF]
, 2015 What makes a high-quality biomarker experiment The success of personalised medicine hinges on the answer to this question. In this paper, I argue that judgment about the quality of biomarker experiments is mediated by the problem of theoretical ...
Hey, Spencer Phillips +1 more
core +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Alpha-fetoprotein: from a diagnostic biomarker to a key role in female fertility
, 2007 Alpha-fetoprotein (AFP) is a well-known diagnostic biomarker used in medicine to detect fetal developmental anomalies such as neural tube defects or Down’s syndrome, or to follow up the development of tumors such as hepatocellular carcinomas.
Bakker, Julie +3 more
core
Diagnostic statistics of combined biomarker levels (sHER2, CA15.3 and CEA).
, 2020 Diagnostic statistics of combined biomarker levels (sHER2, CA15.3 and CEA).
Mathieu Boissan (8262003) +8 more
core +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Exosomal miR-320e as a Novel Potential Biomarker for Cerebral Small Vessel Disease
International Journal of General Medicine, 2023 Ke-Jin Gao,1 Rui-Hua Yin,1 Yuan Wang,1 Zheng Wang,1 Ai-Jun Ma1,2 1Department of Neurology, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, People’s Republic of China; 2Institute of Cerebrovascular, The Affiliated Hospital of ...
Gao KJ, Yin RH, Wang Y, Wang Z, Ma AJ
doaj
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source