Results 61 to 70 of about 1,233,861 (297)

Predicting the Future Burden of Renal Replacement Therapy in Türkiye Using National Registry Data and Comparative Modeling Approaches

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic kidney disease is a growing public health problem worldwide, and the number of patients requiring renal replacement therapy is steadily increasing. Türkiye has experienced a similar rise in both the incidence and prevalence of renal replacement therapy over the past decades; however, national‐level projections of future ...
Arzu Akgül, Neriman Sıla Koç, Berrak Itır Aylı   +2 more
wiley   +1 more source

Lab on a bead with oscillatory centrifugal microfluidics for fast and complete mixing enables fast and accurate biomedical assays

Scientific Reports
Rapid mixing and precise timing are key for accurate biomedical assay measurement, particularly when the result is determined as the rate of a reaction: for example rapid immunoassay in which the amount of captured target is kinetically determined ...
David E. Williams, Wei Li, Mithileshwari Chandrasekhar, Carsten Ma On Wong Corazza, Gerrit Sjoerd Deijs, Lionel Djoko, Bhavesh Govind, Ellen Jose, Yong Je Kwon, Tiffany Lowe, Anil Panchal, Gabrielle Reshef, Matheus J. T. Vargas, M. Cather Simpson   +13 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Development and analytical performance of a new research use only (RUO) GP73 automated immunoassay

Biochemistry and Biophysics Reports
Golgi protein 73 (GP73) is a serum marker with potential applications in the assessment of chronic liver disease progression. We developed a research use only (RUO) GP73 immunoassay to detect serum GP73 concentration.
Shaohua Ning, Enfu Liu, Fanju Meng, Fei Chen, James Hartnett, Zhihong Lin, Bailin Tu, David J. Hawksworth, Bryan C. Tieman, De Yu Mao, Ryan Piktel, Amit Kumar, You Pan, Philip M. Hemken   +13 more
doaj   +1 more source

Extracellular vesicles from plasma have higher tumour RNA fraction than platelets

Journal of Extracellular Vesicles, 2020
In addition to Circulating Tumour Cells (CTCs), cell-free DNA (cfDNA) and Extracellular Vesicles (EVs), the notion of “Tumour-Educated Platelets” (TEP) has recently emerged as a potential source of tumour-derived biomarkers accessible through blood ...
Kay Brinkman, Lisa Meyer, Anne Bickel, Daniel Enderle, Carola Berking, Johan Skog, Mikkel Noerholm   +6 more
doaj   +1 more source

The T2-FLAIR Mismatch Sign as an Imaging Indicator of IDH-Mutant, 1p/19q Non-Codeleted Lower Grade Gliomas: A Systematic Review and Diagnostic Accuracy Meta-Analysis

, 2021
Antonis Adamou, Eleftherios Beltsios, Panagiotis Papanagiotou   +2 more
openalex   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source

Proteomics-Based Identification of Diagnostic Biomarkers Related to Risk Factors and Pathogenesis of Ischemic Stroke [PDF]

, 2020
Jiyeong Lee, Arum Park, Sora Mun, Hyo‐Jin Kim, Hyunsong Son, Hyebin Choi, Doojin Kim, Soo Joo Lee, Jae Guk Kim, Hee‐Gyoo Kang   +9 more
openalex   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source