Results 41 to 50 of about 57,821 (287)

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu   +8 more
wiley   +1 more source

Delay-dependent stability conditions for fundamental characteristic functions [PDF]

open access: yes, 2023
summary:This paper is devoted to the investigation on the stability for two characteristic functions $f_1(z) = z^2+pe^{-z\tau }+q$ and $f_2(z) = z^2+pz e^{-z\tau }+q$, where $p$ and $q$ are real numbers and $\tau >0$.
Matsunaga, Hideaki
core   +1 more source

Time-Varying Transformation-Based Adaptive Tracking Control of Uncertain Robotic Systems With Event-Triggered Mechanism

open access: yesIEEE Access, 2022
In this paper, an adaptive global event-triggered control scheme for uncertain robotic systems, capable of guaranteeing adjustable tracking performance, is developed. Compared with most of the existing results, the proposed control exhibits some features.
Lei Zhang   +4 more
doaj   +1 more source

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman   +7 more
wiley   +1 more source

Novel Approach to Analyze All-Round Kinematic Stability During Curving Steps

open access: yesIEEE Access, 2023
From the viewpoint of the stability of biped walking, the stability for both anteroposterior, lateral, and diagonal directions should be considered owing to the frequent occurrence of turning and curving motions in the daily environment. In this study, a
Yasuhiro Akiyama   +3 more
doaj   +1 more source

A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho   +7 more
wiley   +1 more source

A characterization of Lyapunov diagonal stability using hadamard products

open access: yes, 1991
Several new characterizations of Lyapunov diagonal stability are presented. One of the characterizations is used to derive a simple necessary and sufficient condition for Lyapunov diagonal stability of a 3 × 3 ...
Kraaijevanger, J.F.B.M.
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

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