Results 51 to 60 of about 64,065 (260)
On a theorem of Redheffer concerning diagonal stability
Linear Algebra and its Applications, 2009 The authors exploit the Kalman-Yakubovich-Popov lemma to derive necessary and sufficient conditions for a matrix to be diagonally stable. The main results are employed to derive new conditions for the Hurwitz stability for special classes of matrices.
Shorten, Robert, Narendra, Kumpati S.
openaire +2 more sources
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Scientific Reports, 2022 Developmental maturation occurs in slow swimming behavior in larval zebrafish; older larvae acquire the ability to perform slow swimming while keeping their head stable in the yaw dimension.
Kohei Kawano +5 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Optimizing ground control points for UAV photogrammetry: a case study in slope stability mapping
Communications in Science and TechnologyThis study investigated the effect of Ground Control Point (GCP) distribution on the accuracy of UAV-based slope mapping and stability analysis. Three GCP configurations—top-only, vertical, and diagonal—were tested.
Muhammad Hafizhir Ridha +2 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
An exploration of the influence of diagonal dissociation and moderate changes in speed on locomotor parameters in trotting horses [PDF]
PeerJ, 2016 Background. Although the trot is described as a diagonal gait, contacts of the diagonal pairs of hooves are not usually perfectly synchronized. Although subtle, the timing dissociation between contacts of each diagonal pair could have consequences on ...
Sarah Jane Hobbs +2 more
doaj +2 more sources
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Stability Analysis of Marine Scaffold Under Coupled Environmental Loads
Journal of Marine Science and EngineeringStructural instability in marine scaffold systems often causes serious economic losses and casualties. In this study, a multi-parameter coupled model was established based on the MIDAS GEN finite element analysis platform to investigate the influence ...
Pengkai Wang +3 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source