Results 31 to 40 of about 569,284 (129)

Probiotics and intestinal permeability in adults with metabolic dysfunction‐associated steatohepatitis: A secondary analysis of a randomized clinical trial

Journal of Parenteral and Enteral Nutrition, EarlyView.
Abstract Background Metabolic dysfunction‐associated steatohepatitis (MASH) is associated with altered intestinal permeability, allowing microbial products to translocate to the liver via the enterohepatic circulation and contributes to disease progression. The aim of our study was to evaluate the association between probiotic supplementation and serum
Bruna Concheski de Moura, Samanta Catherine Ferreira, Amanda Souza Silva‐Sperb, Helena Abadie Moraes, Larisse Longo, Carolina Uribe‐Cruz, Matheus Truccolo Michalczuk, Themis Reverbel da Silveira, Carlos Thadeu Schmidt Cerski, Mário Reis Álvares da Silva, Valesca Dall'Alba   +10 more
wiley   +1 more source

Synthetic Food Colorants and Gut Microbiota: A Systematic Review of Preclinical Studies

Food Frontiers, Volume 7, Issue 5, September 2026.
ABSTRACT Growing evidence suggests that industrial food processing, including the excess consumption of food additives, might have a negative impact on human health. Despite regulatory safety evaluations, their impact on gut microbiota remains poorly characterized.
Sebastiano Alfio Torrisi, Federica Martina Di Domenico, Gian Marco Leggio, Giuseppe Caruso, Evelyn Frias‐Toral, Nohora Milena Martínez López, Agnieszka Micek, Marialaura Bonaccio, Justyna Godos, Giuseppe Grosso   +9 more
wiley   +1 more source

Optimization of agro-technological processing parameters to enhance diamine oxidase activity in edible legume sprouts

Journal of Agriculture and Food Research
Histamine intolerance is associated with impaired histamine metabolism caused by a deficiency of the enzyme diamine oxidase (DAO). A recommended strategy to alleviate symptoms is a low-histamine diet supplemented with exogenous DAO.
Judit Costa-Catala, Irache Iduriaga-Platero, Jaume Bori, M. Carmen Vidal-Carou, M. Luz Latorre-Moratalla, Oriol Comas-Basté   +5 more
doaj   +1 more source

Satellite Glial Cells Synthesize and Release GABA to Activate Extrasynaptic GABAA Receptors That Modulate Dorsal Root Ganglia Neuron Excitability

Glia, Volume 74, Issue 9, September 2026.
Mechanism of synthesis, release, receptor activation, uptake, and degradation of GABA in dorsal root ganglia (DRG). Left: GABA is synthesized from putrescine in satellite glial cells (SGCs). After being released by Best1 channel, it activates GABAA receptors in sensory neurons, producing a chloride current.
Natalie Jiménez‐Barrios, Ricardo González‐Ramírez, Francisco Javier Paz‐Bermúdez, Guadalupe Raya‐Tafolla, José Segovia Vila, Ricardo Felix, Rodolfo Delgado‐Lezama, Benjamín Florán Garduño   +7 more
wiley   +1 more source

Evaluation of the Safety and Tolerability of Three Single Ascending Doses of Diamine Oxidase (DAO) in Healthy Volunteers: A Randomized Clinical Trial

International Journal of Translational Medicine
Background/Objectives: Diamine oxidase (DAO) enzyme metabolizes dietary histamine in the gastrointestinal tract. DAO deficiency can lead to histamine intolerance (HIT), manifesting as migraines, gastrointestinal disturbances, and allergic reactions.
Pol Molina Perelló, Montse Puntes Rodríguez, Jimena Coimbra Hurtado, Maite Garrido Sánchez, Marta Castillo Ocaña, David Martínez Bonifacio, Lydia Carrera Marcolin, Jordi Cuñé Castellana, Rosa Antonijoan Arbós   +8 more
doaj   +1 more source

Bile acid metabolism and signaling in human and animal health: A One Health perspective

iMetaOmics, Volume 3, Issue 3, September 2026.
Bile acids maintain host homeostasis through enterohepatic circulation, microbial transformation, and bile acid receptor signaling, thereby regulating glucose and lipid metabolism, intestinal barrier integrity, and immunity. These effects support human disease intervention and health‐oriented animal production, reducing drug dependence and residue ...
Lei Li, Shuai Liu, Zhijun Cao, Yangchun Cao, Shengru Wu, Lu Deng, Junhu Yao, Jun Zhang   +7 more
wiley   +1 more source

Association of intestinal mucosal barrier function with intestinal microbiota in Spleen-Kidney Yang Deficiency IBS-D mice

Frontiers in Microbiology
BackgroundTo establish and evaluate an IBS-D mouse model with Spleen-Kidney Yang Deficiency, explore the microecological mechanisms of IBS-D, and provide experimental evidence for the clinical diagnosis and treatment of IBS-D with Spleen-Kidney Yang ...
Liwen Li, Liwen Li, Qi Long, Qi Long, Na Deng, Na Deng, Zhoujin Tan, Zhoujin Tan   +7 more
doaj   +1 more source

A Review on Heat Stress in Broiler Chickens: Mechanisms, Effects and Mitigation Strategies

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Heat stress caused by high temperature and humidity compromises broiler health, welfare, and productivity by reducing feed intake, growth performance, and feed efficiency, while increasing mortality, oxidative stress, metabolic disturbances, intestinal dysfunction, gut dysbiosis, immune suppression, and meat quality deterioration.
Maksuda Begum, Laura Musa, Guido Grilli, Dilşan Akçay, Md Golam Kibria, Mst. Mayeeda Parvin, Sabiha Zarin Tasnim Bristi, Md Jisan Ahmed, Delower Hossain   +8 more
wiley   +1 more source

Merging Biocatalysis and Chemocatalysis in Flow: State‐of‐the‐Art and Future Directions for Sustainable Synthesis

Angewandte Chemie, Volume 138, Issue 25, 15 June 2026.
This review highlights recent advances in integrating biocatalysis and chemocatalysis in continuous flow to create streamlined, sustainable processes. It examines chemo‐enzymatic cascades combining at least one enzymatic and one chemical step, discusses challenges such as enzyme immobilization, leaching, and reactor clogging, and presents solutions ...
Petros Siasiaridis, Matteo Damian, Francesco G. Mutti   +2 more
wiley   +2 more sources

Histamine intolerance, DAO deficiency and their impact on health in the context of migraine development and treatment: a review

Journal of Education, Health and Sport
Introduction and purpose  Migraine is a prevalent neurological disorder affecting up to 1 billion individuals worldwide. Histamine intolerance, caused by reduced activity of the diamine oxidase enzyme, has been increasingly linked to migraines, with ...
Agata Białek, Magdalena Mendak, Anna Hanslik, Agnieszka Walczak , Adrian Hovagimyan , Monika Olszanecka, Tomasz Olszanecki   +6 more
doaj   +1 more source