Results 131 to 140 of about 43,999 (267)

Tissue‐Resident Macrophage‐Derived E3 Ligase SMURF2 Restricts Autoimmune Inflammation by Mediating the Degradation of p‐TBK1

Advanced Science, Volume 13, Issue 7, 3 February 2026.
Dysregulated Tissue resident macrophage (TRMs) link to autoimmune inflammation. SMURF2 mediates Lys‐27 (K27)‐linked ubiquitination of p‐TBK1 and its degradation, which inhibits CSF1R signaling‐triggered TRM proliferation, thereby restraining the autoimmune inflammation.
Xiang An, Jun Li, Lingling Wang, Chengyuan Li, Zhenpeng Jin, Yushi Yao, Minmin Jiang, Wenlong Lin, Xiaojian Wang   +8 more
wiley   +1 more source

Idiopathic AIDS enteropathy and treatment of gastrointestinal opportunistic pathogens. [PDF]

, 2009
Diarrhea in patients with acquired immune deficiency syndrome (AIDS) has proven to be both a diagnostic and treatment challenge since the discovery of the human immunodeficiency virus (HIV) virus more than 30 years ago.
Cello, John P, Day, Lukejohn W
core  

Cadherin‐26 Facilitates Transepithelial Migration of Eosinophils in Eosinophilic Chronic Rhinosinusitis

International Forum of Allergy &Rhinology, Volume 16, Issue 2, Page 138-151, February 2026.
ABSTRACT Background Eosinophilic chronic rhinosinusitis with nasal polyps (eCRSwNP) is characterized by persistent sinonasal inflammation and marked eosinophilic infiltration. Although the relationship between eosinophils and NP formation has been extensively studied, the mechanisms governing eosinophil transepithelial migration into the nasal mucosa ...
Yeong‐In Jo, Jee Won Moon, Joo‐Hoo Park, Hwa Eun Yang, Subin Cho, Hyeongguk Son, Hyun‐Woo Yang, Il‐Ho Park   +7 more
wiley   +1 more source

The Redox Properties of Polyphenols and Their Role in ROS Generation for Biomedical Applications

Angewandte Chemie, Volume 138, Issue 3, 16 January 2026.
The dual redox nature of polyphenols enables antioxidant activity and controlled reactive oxygen species (ROS) generation. This review details the biomedical applications of polyphenols in materials such as nanoparticles, coatings, and hydrogels for antimicrobial, tissue regeneration, and cancer therapies.
Jose Bolaños‐Cardet, Belén Pepió‐Tárrega, Javier Saiz‐Poseu, Alba López‐Moral, Faiz Ullah, Victor J. Yuste, Daniel Ruiz‐Molina, Salvio Suárez‐García   +7 more
wiley   +2 more sources

Engineering a Perfusion Bioreactor System for hiPSC‐Derived Progenitor Co‐Culture Capturing Microglial Features in CNS Development

Biotechnology and Bioengineering, Volume 123, Issue 2, Page 363-378, February 2026.
The authors report the development of a controlled and scalable 3D co‐culture system combining hiPSC‐derived erythromyeloid progenitors and neurospheres within the Ambr® 250 Modular platform operated with a newly designed perfusion system. This model faithfully recapitulates early microglia–neural interactions, enabling progenitor integration ...
Catarina M. Gomes, Inês de Sá, Margarida Delgado, Paula M. Alves, Catarina Brito   +4 more
wiley   +1 more source

Comparative Insights into Acute Gastroenteritis in Cattle Caused by Bovine Rotavirus A and Bovine Coronavirus

Veterinary Sciences
Acute gastroenteritis (AGE) in cattle significantly impacts the economy due to relatively high morbidity and mortality and decreased production. Its multifactorial nature drives its global persistence, involving enteric viruses, bacteria, protozoa, and ...
Vjekoslava Kostanić, Valentina Kunić, Marina Prišlin Šimac, Marica Lolić, Tomislav Sukalić, Dragan Brnić   +5 more
doaj   +1 more source

RVLM C1 Neurons Innervate Sacral as well as Thoracolumbar Autonomic Preganglionic Neurons in the Rat

Journal of Comparative Neurology, Volume 534, Issue 2, February 2026.
Axons expressing the adrenaline‐synthesizing enzyme, phenylethanolamine N‐methyltransferase (PNMT), project widely throughout the spinal cord. Many of these axons are from C1 neurons of the rostral ventrolateral medulla. We confirm that dense arrays of PNMT‐expressing, C1‐derived axons surround thoracolumbar sympathetic preganglionic neurons, many of ...
I. J. Llewellyn‐Smith, L. Travis, A. A. Connelly, J. K. Bassi, C. Menuet, A. M. Allen   +5 more
wiley   +1 more source

Immunological response of locally prepared oil adjuvanted pneumo-5 vaccine in calves

Journal of Veterinary Medical Research, 2017
he present study aimed to prepare a combined inactivated vaccine containing bovine viral diarrhea genotype-1(BVD-1),bovine viral diarrhea genotype-2 (BVD-2), infectious bovine rhinotracheitis (IBR),parainfluenza-3 (PI-3) and bovine respiratory syncytial ...
Rasha,I.EL-Hawary, Hanaa A. Mostafa
doaj  

Development of a one-step multiplex RT-qPCR method for rapid detection of bovine diarrhea viruses

Frontiers in Cellular and Infection Microbiology
IntroductionViral calf diarrhea poses a significant challenge to the cattle industry worldwide due to its high morbidity and mortality rates, leading to substantial economic losses.
Dequan Yang, Li Ma, Zhongping Yang, Xianchao Yang, Jian Wang, Houbin Ju, Chunguang Lu, Yonggang Weng, Heping Zhao, Haixiao Shen, Xin Li, Feifei Ge, Xiaoxu Wang, Xiujuan Wu, Meng Xiang, Guidan Feng, Congsheng Tang, Shixin Huang, Hongjin Zhao   +18 more
doaj   +1 more source

Ricinus Communis: Nutritional Importance, Health Benefits, and Industrial Applications

eFood, Volume 7, Issue 1, February 2026.
The current paper summarizes the nutritional composition, phytochemistry, health benefits, safety studies, and applications of castor beans and their oil. Moreover, the diverse bioactive compounds, including saponins, emodins, terpenoids, anthraquinones, flavonoids, steroids, and alkaloids, exhibit therapeutic properties such as antioxidant, anticancer,
Hassan Raza, Muhammad Tauseef Sultan, Asad Abbas, Aimen Mazhar, Ahmad Mujtaba Noman, Muhammad Imran, Muzzamal Hussain, Ehab M. Mostafa, Ahmed H. El‐Ghorab, Mohammed M. Ghoneim, Samy Selim, Mohamed A. Abdelgawad, Anjuman Gul Memon, Entessar Al Jbawi   +13 more
wiley   +1 more source