Results 81 to 90 of about 28,098 (249)

Application of Bovine Nasal Epithelial Cells as an In Vitro Model for Studying Viral Infection in the Upper Respiratory Tract

Viruses
Bovine respiratory disease complex (BRDC) is a multifactorial and globally prevalent condition involving a combination of viral and bacterial pathogens, as well as environmental stressors.
Malte Pitters, Henrik Fritsch, Ang Su, Klaus Jung, Paul Becher   +4 more
doaj   +1 more source

Single Pathogen Challenge with Agents of the Bovine Respiratory Disease Complex. [PDF]

PLoS ONE, 2015
Bovine respiratory disease complex (BRDC) is an important cause of mortality and morbidity in cattle; costing the dairy and beef industries millions of dollars annually, despite the use of vaccines and antibiotics.
Laurel J Gershwin, Alison L Van Eenennaam, Mark L Anderson, Heather A McEligot, Matt X Shao, Rachel Toaff-Rosenstein, Jeremy F Taylor, Holly L Neibergs, James Womack, Bovine Respiratory Disease Complex Coordinated Agricultural Project Research Team   +9 more
doaj   +1 more source

Herd-level prevalence of selected endemic infectious diseases of dairy cows in Great Britain [PDF]

, 2017
To implement appropriate and effective disease control programs at the national level, up-to-date and unbiased information on disease frequency is needed. The aim of this study was to estimate the prevalence of selected endemic infectious diseases in the
Chengat Prakashbabu, B, Damaso, A, Gibbons, J, Green, M, Guitian, J, Longbottom, D, Van Winden, S C L, Velasova, M, Wheelhouse, N   +8 more
core   +7 more sources

Nonviral Gold Nanoparticle‐Mediated Delivery of CRISPR‐Cas9 Ribonucleoprotein and Long DNA Transgenes Into Primary Blood Cells

Advanced NanoBiomed Research, EarlyView.
CRISPR/Cas9 has revolutionized the field of gene therapy, but delivery remains an outstanding issue. We propose a nonviral gold‐nanoparticle platform for co‐delivery of CRISPR/Cas9 ribonucleoprotein and long 2.1 kilobase dsDNA transgene constructs. This CRISPR‐AuNP is inexpensive to produce and mediate gene editing and DNA delivery in T cells and CD34+
Rachel A. Cunningham, Karthikeya S. V. Gottimukkala, Daniel D. Lane, Katrina Poljakov, Patricia Lipson, Mark R. Enstrom, Alessandro Rizzi, Aude G. Chapuis, Jennifer E. Adair   +8 more
wiley   +1 more source

A multiplex real-time fluorescence-based quantitative PCR assay for calf diarrhea viruses

Frontiers in Microbiology
IntroductionCalf diarrhea is a significant condition that has a strong effect on the cattle industry, resulting in huge economic losses annually. Bovine torovirus (BToV), bovine enterovirus (BEV), bovine norovirus (BNoV), bovine coronavirus (BCoV ...
Wenxin Meng, Wenxin Meng, Zihan Chen, Zihan Chen, Qifeng Jiang, Qifeng Jiang, Jinping Chen, Jinping Chen, Xiaoying Guo, Xiaoying Guo, Zihang Ma, Zihang Ma, Kun Jia, Kun Jia, Shoujun Li, Shoujun Li   +15 more
doaj   +1 more source

Evidence of shared bovine viral diarrhea infections between red deer and extensively raised cattle in south-central Spain [PDF]

, 2016
Bovine viral diarrhea virus (BVDV) is a pestivirus that affects cattle production worldwide and that can infect other ungulates such as cervids and even wild boar (Sus scrofa).
de las Heras, Ana Isabel, Kukielka, Deborah, Martínez López, Beatriz, Rivera Arroyo, Belén, Rodríguez Prieto, Víctor, Sánchez-Vizcaíno, José Manuel, Vicente, Joaquín   +6 more
core   +2 more sources

A Rare RIPK3 Variant Enhances Necroptosis and Promotes Inflammation in a Still Disease–Like Autoinflammatory Syndrome

Arthritis &Rheumatology, EarlyView.
Objective Still disease represents a prototypical polygenic systemic autoinflammatory disease, characterized by recurrent systemic inflammation and dysregulation of innate immunity. Despite extensive clinical characterization, familial clustering Still disease remains unreported.
Longfang Chen, Qihua Dai, Yu Xiao, Jialin Dai, Mengyan Wang, Yuning Ma, Yujie Shen, Zhimo Xu, Jianfen Meng, Xia Chen, Da Yi, Yue Sun, Hui Shi, Honglei Liu, Xiaobing Cheng, Yutong Su, Junna Ye, Huihui Chi, Zhuochao Zhou, Tingting Liu, Jialin Teng, Chengde Yang, Jinchao Jia, Qiongyi Hu   +23 more
wiley   +1 more source

Influenza Viral Manipulation of Sphingolipid Metabolism and Signaling to Modulate Host Defense System

Scientifica, 2014
Viruses attempt to create a distinctive cellular environment to favor viral replication and spread. Recent studies uncovered new functions of the sphingolipid signaling/metabolism during pathogenic virus infections.
Madhuvanthi Vijayan, Bumsuk Hahm
doaj   +1 more source

Characterization of monoclonal and polyclonal antibodies to bovine enteric coronavirus: Establishment of an efficient ELISA for antigen detection in feces [PDF]

, 1989
Monoclonal antibodies to bovine enteric coronavirus (BEC) were produced. Additionally, polyclonal antibodies were made in rabbits and guinea pigs and extracted from the yolk of immunized hens.
Czerny, C. P., Eichhorn, Werner
core   +1 more source

Design Space Assessment of Virus Inactivation in Plasma‐Derived Matrices Establishes a Single Detergent Alternative to TX‐100‐Containing Mixes

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The detergent Triton X‐100 (TX‐100) is a typical component of solvent/detergent (S/D) mixes applied for virus inactivation steps of biomanufacturing processes, yet environmentally unfavorable properties have led to restrictions on its use. Deviron 13‐S9 has recently been described as an eco‐friendly TX‐100 alternative, with powerful virus ...
Johanna Kindermann, Cecilie Klausen, Michael Karbiener, Thomas R. Kreil   +3 more
wiley   +1 more source